Abstract: A position guidance system for minimally invasive medical procedures includes a medical device having a first end configured for percutaneous insertion and a second end configured to remain exterior to a patient's skin, a hub connection provided at the second end of the medical device, at least one bubble level including a bubble configured to provide a visual indication of a deviation from a target angle for medical device insertion, and a connector configured to reversibly and repeatedly connect the bubble level to the hub connection of the medical device. When the bubble is positioned at a center of the bubble level, an actual insertion angle of the medical device is the same as the target angle. When the bubble is positioned off-center of the bubble level, the actual insertion angle of the medical device deviates from the target angle.

Abstract: A position guidance system for minimally invasive medical procedures includes a medical device having a first end configured for percutaneous insertion and a second end configured to remain exterior to a patient's skin, a hub connection provided at the second end of the medical device, at least one bubble level including a bubble configured to provide a visual indication of a deviation from a target angle for medical device insertion, and a connector configured to reversibly and repeatedly connect the bubble level to the hub connection of the medical device. When the bubble is positioned at a center of the bubble level, an actual insertion angle of the medical device is the same as the target angle. When the bubble is positioned off-center of the bubble level, the actual insertion angle of the medical device deviates from the target angle.

Abstract: Disclosed herein is a system useful for obtaining magnetic resonance imaging data of longterm tissue slice cultures that typically survive well beyond 12 hours after tissue procurement. The system comprises a first support member comprising a perimeter defining a first interior space and a second support member. The first and second support members are configured such that they can secure a substrate having a live tissue sample disposed thereon when said first and second support members are brought together. Further, the system comprises a chamber into which the first and second support members, when brought together, may be disposed. Also disclosed herein is a method of producing magnetic resonance imaging data from a live tissue sample, said method comprising obtaining a tissue sample comprising live cells, culturing said tissue sample under conditions to keep cells of said tissue alive for at least 12 hours, and subjecting said tissue sample to magnetic resonance imaging.