Patents by Inventor Timothy Pelletier
Timothy Pelletier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11821032Abstract: The present invention provides methods, compositions, mixtures and kits utilizing 5-Chloro-2-methyl-4-isothiazolin-3-one in sequencing reactions, and in particular, sequencing reactions where deoxynucleoside triphosphates comprising a 3?-O position capped by a disulfide-based 3?-terminator group are used. In one embodiment, the deoxynucleoside triphosphates comprise a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. In addition, thiol-containing compounds and scavengers of thio-containing compounds are described. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.Type: GrantFiled: August 21, 2020Date of Patent: November 21, 2023Assignee: IsoPlexis CorporationInventors: Luisa Andruzzi, Jimmy Adediran, Timothy Pelletier, Austin Ricker, Angela DeLucia, Ben McNally, Dona Hevroni, Mong Sano Marma, John Andrew Sheridan
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Publication number: 20230340583Abstract: The present invention provides methods, compositions, mixtures and kits utilizing 5-Chloro-2-methyl-4-isothiazolin-3-one in sequencing reactions, and in particular, sequencing reactions where deoxynucleoside triphosphates comprising a 3?-O position capped by a disulfide-based 3?-terminator group are used. In one embodiment, the deoxynucleoside triphosphates comprise a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. In addition, thiol-containing compounds and scavengers of thio-containing compounds are described. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.Type: ApplicationFiled: April 6, 2023Publication date: October 26, 2023Inventors: Luisa ANDRUZZI, Jimmy ADEDIRAN, Timothy PELLETIER, Austin RICKER, Angela DELUCIA, Ben MCNALLY, Dona HEVRONI, Mong Sano MARMA, John Andrew SHERIDAN
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Publication number: 20210403985Abstract: The invention relates to methods, compositions, devices, systems and kits as described including, without limitation, reagents and mixtures for determining the identity of nucleic acids in nucleotide sequences using, for example, sequencing by synthesis methods. In particular, the present invention contemplates the use of photoprotective mixture of compounds as imaging reagents to improve stability and storage of fluorescent compounds, including but not limited to, nucleotides with fluorescent labels.Type: ApplicationFiled: September 10, 2021Publication date: December 30, 2021Inventors: Luisa ANDRUZZI, Michel Georges PERBOST, Dona HEVRONI, Minakshi GUHA, Austin RICKER, Timothy PELLETIER
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Patent number: 11162129Abstract: The invention relates to methods, compositions, devices, systems and kits as described including, without limitation, reagents and mixtures for determining the identity of nucleic acids in nucleotide sequences using, for example, sequencing by synthesis methods. In particular, the present invention contemplates the use of photoprotective mixture of compounds as imaging reagents to improve stability and storage of fluorescent compounds, including but not limited to, nucleotides with fluorescent labels.Type: GrantFiled: October 31, 2017Date of Patent: November 2, 2021Assignee: IsoPlexis CorporationInventors: Luisa Andruzzi, Michel Georges Perbost, Dona Hevroni, Minakshi Guha, Austin Ricker, Timothy Pelletier
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Publication number: 20210002720Abstract: The present invention provides methods, compositions, mixtures and kits utilizing 5-Chloro-2-methyl-4-isothiazolin-3-one in sequencing reactions, and in particular, sequencing reactions where deoxynucleoside triphosphates comprising a 3?-O position capped by a disulfide-based 3?-terminator group are used. In one embodiment, the deoxynucleoside triphosphates comprise a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. In addition, thiol-containing compounds and scavengers of thio-containing compounds are described. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.Type: ApplicationFiled: August 21, 2020Publication date: January 7, 2021Inventors: Luisa Andruzzi, Jimmy Adediran, Timothy Pelletier, Austin Ricker, Angela DeLucia, Ben McNally, Dona Hevroni, Mong Sano Marma, John Andrew Sheridan
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Patent number: 10844430Abstract: The present invention provides methods, compositions, mixtures and kits utilizing 5-Chloro-2-methyl-4-isothiazolin-3-one in sequencing reactions, and in particular, sequencing reactions where deoxynucleoside triphosphates comprising a 3?-O position capped by a disulfide-based 3?-terminator group are used. In one embodiment, the deoxynucleoside triphosphates comprise a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. In addition, thiol-containing compounds and scavengers of thio-containing compounds are described. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.Type: GrantFiled: January 24, 2018Date of Patent: November 24, 2020Assignee: Qiagen Sciences, LLCInventors: Luisa Andruzzi, Jimmy Adediran, Timothy Pelletier, Austin Ricker, Angela DeLucia, Ben McNally, Dona Hevroni, Mong Sano Marma, John Andrew Sheridan
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Patent number: 10575649Abstract: A knee-rest economic chair is provided. The knee-rest economic chair is formed from a unitary construction, fastener-less assembly, wherein the chair provides an elevated posterior condition as an elevated knee rest for seated users. The chair may be assembled from a plurality of components all of which are formed from a planar blank of one material. The components have tabs and slots for joined adjacent components that results in a seat component spaced apart and elevated above a knee support component, positioned relative to each other in an elevated posterior position, wherein gravity secures the resulting tab-slot and slot-slot joints, making separate fasteners unnecessary.Type: GrantFiled: June 11, 2018Date of Patent: March 3, 2020Inventor: Mead Timothy Pelletier
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Publication number: 20190226018Abstract: The present invention provides methods, compositions, mixtures and kits utilizing 5-Chloro-2-methyl-4-isothiazolin-3-one in sequencing reactions, and in particular, sequencing reactions where deoxynucleoside triphosphates comprising a 3?-O position capped by a disulfide-based 3?-terminator group are used. In one embodiment, the deoxynucleoside triphosphates comprise a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. In addition, thiol-containing compounds and scavengers of thio-containing compounds are described. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.Type: ApplicationFiled: January 24, 2018Publication date: July 25, 2019Inventors: Luisa Andruzzi, Jimmy Adediran, Timothy Pelletier, Austin Ricker, Angela DeLucia, Ben McNally, Dona Hevroni, Mong Sano Marma, John Andrew Sheridan
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Publication number: 20180352963Abstract: A knee-rest economic chair is provided. The knee-rest economic chair is formed from a unitary construction, fastener-less assembly, wherein the chair provides an elevated posterior condition as an elevated knee rest for seated users. The chair may be assembled from a plurality of components all of which are formed from a planar blank of one material. The components have tabs and slots for joined adjacent components that results in a seat component spaced apart and elevated above a knee support component, positioned relative to each other in an elevated posterior position, wherein gravity secures the resulting tab-slot and slot-slot joints, making separate fasteners unnecessary.Type: ApplicationFiled: June 11, 2018Publication date: December 13, 2018Inventor: Mead Timothy Pelletier
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Publication number: 20180127809Abstract: The invention relates to methods, compositions, devices, systems and kits as described including, without limitation, reagents and mixtures for determining the identity of nucleic acids in nucleotide sequences using, for example, sequencing by synthesis methods. In particular, the present invention contemplates the use of photoprotective mixture of compounds as imaging reagents to improve stability and storage of fluorescent compounds, including but not limited to, nucleotides with fluorescent labels.Type: ApplicationFiled: October 31, 2017Publication date: May 10, 2018Inventors: Luisa Andruzzi, Michael Georges Perbost, Dona Hevroni, Minakshi Gupta, Austin Ricker, Timothy Pelletier
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Patent number: 5785379Abstract: A modular picnic table with attached individual seats facing each other on opposite ends of a single multimembered frame part, constructed of either tubular aluminum, metal or tubular reinforced plastic. A plurality of multimembered frame parts connected in series by bolts and nuts and connector frame part to provide an unlimited modular seating frame system. A flat surface seat with support post part, interchanges with an angled ergo seat and knee rest support post part to connect to multimembered frame part in an existing frame form. End seating to table is provided by a distinctive modular part in modified shape of multimembered frame part. The multimembered end seat part attaches as optional individual seat and frame support.Type: GrantFiled: July 31, 1996Date of Patent: July 28, 1998Inventor: Mead Timothy Pelletier