Patents by Inventor Timothy R. Hansen
Timothy R. Hansen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240115001Abstract: An article of footwear includes an upper including a chamber, a compressible component disposed within the chamber and operable between a relaxed state and a constricted state, a sole structure including a recess forming a cavity, and a pump device disposed within the cavity and fluidly coupled to the chamber, the pump device operable to transition the compressible component from the relaxed state to the constricted state by removing fluid from the chamber.Type: ApplicationFiled: October 10, 2023Publication date: April 11, 2024Applicant: NIKE, Inc.Inventors: Jennifer L. Bishop, Timothy P. Hopkins, Nicholas R. Long, Nadia M. Panian, Aaron K. Seid, Richard Kristian Hansen
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Patent number: 11878965Abstract: The present disclosure relates to novel compounds for use in therapeutic treatment of a disease associated with peptidylarginine deiminases (PADs), such as peptidylarginine deiminase type 4 (PAD4). The present disclosure also relates to processes and intermediates for the preparation of such compounds, methods of using such compounds and pharmaceutical compositions comprising the compounds described herein.Type: GrantFiled: December 21, 2021Date of Patent: January 23, 2024Assignee: Gilead Sciences, Inc.Inventors: Daniel H. Byun, Zhenhong R. Cai, Eda Y. Canales, Laurent P. Debien, Timothy R. Hansen, Richard Huang, Petr Jansa, Rick A. Lee, Jennifer A. Loyer-Drew, Ryan McFadden, Michael L. Mitchell, Hyung-Jung Pyun, Roland D. Saito, Michael S. Sangi, Adam J. Schrier, Marina E. Shatskikh, James G. Taylor, Joshua J. Van Veldhuizen, Lianhong Xu
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Publication number: 20230090053Abstract: The present disclosure relates to novel compounds for use in therapeutic treatment of a disease associated with peptidylarginine deiminases (PADs), such as peptidylarginine deiminase type 4 (PAD4). The present disclosure also relates to processes and intermediates for the preparation of such compounds, methods of using such compounds and pharmaceutical compositions comprising the compounds described herein.Type: ApplicationFiled: December 21, 2021Publication date: March 23, 2023Inventors: Daniel H. Byun, Zhenhong R. Cai, Eda Y. Canales, Laurent P. Debien, Timothy R. Hansen, Richard Huang, Petr Jansa, Rick A. Lee, Jennifer A. Loyer-Drew, Ryan McFadden, Michael L. Mitchell, Hyung-Jung Pyun, Roland D. Saito, Michael S. Sangi, Adam J. Schrier, Marina E. Shatskikh, James G. Taylor, Joshua J. Van Veldhuizen, Lianhong Xu
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Publication number: 20210116471Abstract: A method and automated apparatus for locating and selecting a colony of microorganisms on a culture dish and subjecting the obtained sample to a plurality of downstream tests including a test to identify the microorganism and a test to identify the susceptibility of the microorganism to antibiotics. The method includes the automated steps of locating and selecting a colony of microorganisms on a culture dish; obtaining a sample of the selected colony of microorganisms; preparing a suspension of a sample of microorganisms automatically by submerging the pick tool with the sample in a suspension, after which the pick tool is vibrated in at least the vertical direction to release the sample from the pick tool in the suspension. The turbidity of the suspension is monitored to ensure that the concentration of microorganism in suspension is sufficient so that the suspension is used a source for sample for both identification and antibiotic susceptibility of the microorganisms in the sample.Type: ApplicationFiled: December 29, 2020Publication date: April 22, 2021Applicant: BD KIESTRA B.V.Inventors: Timothy R. Hansen, Rick Holtz, Martijn Kleefstra, Raphael Rodolphe Marcelpoil, Rick Pierpont, Brent Ronald Pohl, Alyssa Shedlosky, Scott Shindledecker, Edward Skevington, Kerry Lynn Smith, Timothy Wiles
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Patent number: 10758211Abstract: A container for collecting a biological specimen is provided that includes a peripheral wall extending from a base. The container further includes a longitudinal tower disposed within the container. The tower forms a partition within the container to form at least a first chamber and a second chamber therein, wherein the first and second chambers are in fluid communication with one another. In addition, the container includes an insert disposed within the container opposite the base, the insert comprising at least a first opening and a second opening. The second opening provides access to the second chamber and is further configured to engage a specimen collecting device to leave a portion of the specimen collecting device within the second chamber. The first opening provides access to the first chamber and is further configured to receive a syringe therein for accessing the biological specimen. Associated systems and methods are also provided.Type: GrantFiled: September 18, 2018Date of Patent: September 1, 2020Assignee: BECTON DICKINSON AND COMPANYInventors: Timothy R. Hansen, Mark Talmer, Kevin Bailey, Dwight Livingston
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Publication number: 20190015083Abstract: A container for collecting a biological specimen is provided that includes a peripheral wall extending from a base. The container further includes a longitudinal tower disposed within the container. The tower forms a partition within the container to form at least a first chamber and a second chamber therein, wherein the first and second chambers are in fluid communication with one another. In addition, the container includes an insert disposed within the container opposite the base, the insert comprising at least a first opening and a second opening. The second opening provides access to the second chamber and is further configured to engage a specimen collecting device to leave a portion of the specimen collecting device within the second chamber. The first opening provides access to the first chamber and is further configured to receive a syringe therein for accessing the biological specimen. Associated systems and methods are also provided.Type: ApplicationFiled: September 18, 2018Publication date: January 17, 2019Applicant: BECTON DICKINSON AND COMPANYInventors: Timothy R. Hansen, Mark Talmer, Kevin Bailey, Dwight Livingston
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Patent number: 10123785Abstract: A container for collecting a biological specimen is provided that includes a peripheral wall extending from a base. The container further includes a longitudinal tower disposed within the container. The tower forms a partition within the container to form at least a first chamber and a second chamber therein, wherein the first and second chambers are in fluid communication with one another. In addition, the container include an insert disposed within the container opposite the base, the insert comprising at least a first opening and a second opening. The second opening provides access to the second chamber and is further configured to engage a specimen collecting device to leave a portion of the specimen collecting device within the second chamber. The first opening provides access to the first chamber and is further configured to receive a syringe therein for accessing the biological specimen. Associated systems and methods are also provided.Type: GrantFiled: July 1, 2015Date of Patent: November 13, 2018Assignee: BECTON DICKINSON AND COMPANYInventors: Timothy R. Hansen, Mark Talmer, Kevin Bailey, Dwight Livingston
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Patent number: 9970868Abstract: Described are devices, methods, and systems that are suitable for rapidly and simultaneously determining the concentration of suspended particles in a sample. The devices, methods, and systems allow for the rapid and simultaneous interrogation of a large number of sample wells in a single vessel, for example, samples contained in a two-dimensional array or micro-titer plate, without the need for moving reading heads or moving the sample vessel. The nephelometry system allows the user to rapidly and simultaneously measure the concentration of the particles in numerous samples, adjust the concentration of the particles in the sample with a sample handling system, and re-measure the concentration of the samples in order to achieve a desired concentration.Type: GrantFiled: August 19, 2014Date of Patent: May 15, 2018Assignee: Becton, Dickinson and CompanyInventors: Klaus W. Berndt, Timothy R. Hansen
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Patent number: 9931644Abstract: A system for automatically processing a biological specimen is provided that includes an elevator comprising a plurality of shelves configured to receive a plurality of sample trays. The trays may comprise a plurality of sample containers containing a sample and having a plurality of respective caps engaged therewith. The trays may further include a plurality of centrifuge tube racks each containing a plurality of centrifuge tubes. The system may include a first transport mechanism, a second transport mechanism and a third transport mechanism. The system may include a chain-of-custody device configured to read identifiers on each of the containers. The system may also include a pipetting device configured to remove a portion from the sample containers and dispense the sample into the centrifuge tubes.Type: GrantFiled: June 24, 2016Date of Patent: April 3, 2018Assignee: Becton, Dickinson and CompanyInventors: Kevin Bailey, Christopher Embres, Donald Gorelick, Timothy R. Hansen, Dwight Livingston, Andre Scherz, Gerard Sevigny, Mark Talmer, Tong Zhou, Spencer Lovette
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Patent number: 9696328Abstract: A system and method for preparing and testing of targeted nucleic acids is presented. The system integrates a pipetter, extractor, assay reader, and other components, including a selectively compliant articulated robot arm (SCARA). This synergistic integration of previously separate diagnostic tools creates a system and method whereby a minimum of human intervention is required. The resulting system provides a substantially more accurate and precise method of isolating, amplifying and detecting targeted nucleic acids for diagnosing diseases.Type: GrantFiled: July 18, 2012Date of Patent: July 4, 2017Assignee: Becton, Dickinson and CompanyInventors: Timothy R. Hansen, Matthew P. Collis, Bradley S. Thomas, Thomas L. Fort
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Publication number: 20160318040Abstract: A system for automatically processing a biological specimen is provided that includes an elevator comprising a plurality of shelves configured to receive a plurality of sample trays. The trays may comprise a plurality of sample containers containing a sample and having a plurality of respective caps engaged therewith. The trays may further include a plurality of centrifuge tube racks each containing a plurality of centrifuge tubes. The system may include a first transport mechanism, a second transport mechanism and a third transport mechanism. The system may include a chain-of-custody device configured to read identifiers on each of the containers. The system may also include a pipetting device configured to remove a portion from the sample containers and dispense the sample into the centrifuge tubes.Type: ApplicationFiled: June 24, 2016Publication date: November 3, 2016Inventors: Kevin Bailey, Christopher Embres, Donald Gorelick, Timothy R. Hansen, Dwight Livingston, Andre Scherz, Gerard Sevigny, Mark Talmer, Tong Zhou, Spencer Lovette
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Publication number: 20160209328Abstract: Described are devices, methods, and systems that are suitable for rapidly and simultaneously determining the concentration of suspended particles in a sample. The devices, methods, and systems allow for the rapid and simultaneous interrogation of a large number of sample wells in a single vessel, for example, samples contained in a two-dimensional array or micro-titer plate, without the need for moving reading heads or moving the sample vessel. The nephelometry system allows the user to rapidly and simultaneously measure the concentration of the particles in numerous samples, adjust the concentration of the particles in the sample with a sample handling system, and re-measure the concentration of the samples in order to achieve a desired concentration.Type: ApplicationFiled: August 19, 2014Publication date: July 21, 2016Applicant: Becton, Dickinson and CompanyInventors: Klaus W. Berndt, Timothy R. Hansen
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Patent number: 9381524Abstract: A system for automatically processing a biological specimen is provided that includes an elevator comprising a plurality of shelves configured to receive a plurality of sample trays. The trays may comprise a plurality of sample containers containing a sample and having a plurality of respective caps engaged therewith. The trays may further include a plurality of centrifuge tube racks each containing a plurality of centrifuge tubes. The system may include a first transport mechanism, a second transport mechanism and a third transport mechanism. The system may include a chain-of-custody device configured to read identifiers on each of the containers. The system may also include a pipetting device configured to remove a portion from the sample containers and dispense the sample into the centrifuge tubes.Type: GrantFiled: November 8, 2012Date of Patent: July 5, 2016Assignee: Becton, Dickinson and CompanyInventors: Kevin Bailey, Christopher Embres, Donald Gorelick, Timothy R. Hansen, Dwight Livingston, Andre Scherz, Gerard Sevigny, Mark Talmer, Tong Zhou, Spencer Lovette
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Publication number: 20150297195Abstract: A container for collecting a biological specimen is provided that includes a peripheral wall extending from a base. The container further includes a longitudinal tower disposed within the container. The tower forms a partition within the container to form at least a first chamber and a second chamber therein, wherein the first and second chambers are in fluid communication with one another. In addition, the container include an insert disposed within the container opposite the base, the insert comprising at least a first opening and a second opening. The second opening provides access to the second chamber and is further configured to engage a specimen collecting device to leave a portion of the specimen collecting device within the second chamber. The first opening provides access to the first chamber and is further configured to receive a syringe therein for accessing the biological specimen. Associated systems and methods are also provided.Type: ApplicationFiled: July 1, 2015Publication date: October 22, 2015Inventors: Timothy R. Hansen, Mark Talmer, Kevin Bailey, Dwight Livingston
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Patent number: 9075039Abstract: A container for collecting a biological specimen is provided that includes a peripheral wall extending from a base. The container further includes a longitudinal tower disposed within the container. The tower forms a partition within the container to form at least a first chamber and a second chamber therein, wherein the first and second chambers are in fluid communication with one another. In addition, the container include an insert disposed within the container opposite the base, the insert comprising at least a first opening and a second opening. The second opening provides access to the second chamber and is further configured to engage a specimen collecting device to leave a portion of the specimen collecting device within the second chamber. The first opening provides access to the first chamber and is further configured to receive a syringe therein for accessing the biological specimen. Associated systems and methods are also provided.Type: GrantFiled: November 8, 2012Date of Patent: July 7, 2015Assignee: Becton, Dickinson and CompanyInventors: Timothy R. Hansen, Mark Talmer, Kevin Bailey, Dwight Livingston
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Publication number: 20120282603Abstract: A system and method for preparing and testing of targeted nucleic acids is presented. The system integrates a pipetter, extractor, assay reader, and other components, including a selectively compliant articulated robot arm (SCARA). This synergistic integration of previously separate diagnostic tools creates a system and method whereby a minimum of human intervention is required. The resulting system provides a substantially more accurate and precise method of isolating, amplifying and detecting targeted nucleic acids for diagnosing diseases.Type: ApplicationFiled: July 18, 2012Publication date: November 8, 2012Inventors: Timothy R. Hansen, Matthew P. Collis, Bradley S. Thomas, Thomas L. Fort
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Publication number: 20110200991Abstract: A system and method for preparing and testing of targeted nucleic acids is presented. The system integrates a pipetter, extractor, assay reader, and other components, including a selectively compliant articulated robot arm (SCARA). This synergistic integration of previously separate diagnostic tools creates a system and method whereby a minimum of human intervention is required. The resulting system provides a substantially more accurate and precise method of isolating, amplifying and detecting targeted nucleic acids for diagnosing diseases.Type: ApplicationFiled: April 26, 2011Publication date: August 18, 2011Inventors: Timothy R. Hansen, Matthew P. Collis, Bradley S. Thomas, Thomas L. Fort
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Publication number: 20090155808Abstract: A system and method for preparing and testing of targeted nucleic acids is presented. The system integrates a pipetter, extractor, assay reader, and other components, including a selectively compliant articulated robot arm (SCARA). This synergistic integration of previously separate diagnostic tools creates a system and method whereby a minimum of human intervention is required. The resulting system provides a substantially more accurate and precise method of isolating, amplifying and detecting targeted nucleic acids for diagnosing diseases.Type: ApplicationFiled: February 11, 2009Publication date: June 18, 2009Inventors: Timothy R. Hansen, Matthew P. Collis, Bradley S. Thomas, Thomas L. Fort
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Publication number: 20040149015Abstract: A system and method for determining when a defective or non-defective pipette tip has been acquired by a robotic device performing a sample transfer, prior to the insertion of the defective pipette tip into the fluid sample, thereby preventing waste of the sample or unacceptable handling of the sample. Furthermore, the system and method can effectively eject pipette tips, and in some circumstances, determine whether the ejection of the pipette tip was successful.Type: ApplicationFiled: February 13, 2002Publication date: August 5, 2004Inventors: Timothy R. Hansen, Gene Alan Benton, Matthew John Armstrong
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Publication number: 20040029260Abstract: A system and method for preparing and testing of targeted nucleic acids is presented. The system integrates a pipetter, extractor, assay reader, and other components, including a selectively compliant articulated robot arm (SCARA). This synergistic integration of previously separate diagnostic tools creates a system and method whereby a minimum of human intervention is required. The resulting system provides a substantially more accurate and precise method of isolating, amplifying and detecting targeted nucleic acids for diagnosing diseases.Type: ApplicationFiled: May 19, 2003Publication date: February 12, 2004Inventors: Timothy R. Hansen, Matthew P. Collis, Bradley S. Thomas, Thomas L. Fort