Abstract: Systems and methods are described for modeling and analyzing utility structures according to applied loads. Particularly, a model engine can utilize inputs related to a utility structure, environmental conditions to which the utility structure is subjected, and engineering standards expected of the utility structure, and analyze the structure's loading and performance based on analysis configuration inputs. An engine or multiple engines can be run locally, or can be instantiated in a cloud to assist with multiple or complex calculations. Hybrid and geometric non-linear analyses and outputs can be performed or provided.

Abstract: Composition and methods are disclosed for utilizing microaggregation of FAP-containing complexes to promote their fast internalization. This approach allows the uptake of cytotoxic cargo coupled to either FAP-Antibodies or FAP-liposome complexes by tumor bladder cells. Importantly, this approach is efficient even under serum-free conditions such as the ones found in the lumen of the bladder.

Abstract: Composition and methods are disclosed for utilizing microaggregation of FAP-containing complexes to promote their fast internalization. This approach allows the uptake of cytotoxic cargo coupled to either FAP-Antibodies or FAP-liposome complexes by tumor bladder cells. Importantly, this approach is efficient even under serum-free conditions such as the ones found in the lumen of the bladder.

Abstract: Composition and methods are disclosed for utilizing micro-aggregation of FAP-containing complexes to promote their fast internalization. This approach allows the uptake of cytotoxic cargo coupled to either FAP-Antibodies or FAP-liposome complexes by tumor bladder cells. Importantly, this approach is efficient even under serum-free conditions such as the ones found in the lumen of the bladder.

Abstract: Composition and methods are disclosed for utilizing micro-aggregation of FAP-containing complexes to promote their fast internalization. This approach allows the uptake of cytotoxic cargo coupled to either FAP-Antibodies or FAP-liposome complexes by tumor bladder cells. Importantly, this approach is efficient even under serum-free conditions such as the ones found in the lumen of the bladder.

Abstract: A novel immunostimulating delivery system is disclosed which provides for generation of a specific antibody response and specific T cell response to delivered antigens. According to the invention, the antigen or a nucleotide encoding the same is contained within, impregnated in or associated with a biocompatible collagen based carrier composition. Methods and compositions for practicing the same are disclosed.

Abstract: The present invention is directed to methods for inhibiting tumor cell growth, causing tumor regression or eliminating tumor cells in a mammal afflicted with a tumor by administering to a TRAIL-sensitive cell a vector having a DNA expression cassette containing a promoter and a DNA sequence encoding TRAIL, wherein the expression of TRAIL results in tumor inhibition, regression or elimination.