Patents by Inventor Tin Chiu LI

Tin Chiu LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and devices for the generation of oocytes with improved oocyte quality for in vitro fertilization procedures using non-invasive cellular transfer
    Patent number: 11851675
    Abstract: The subject invention pertains to methods and devices for generating mature oocytes from immature oocytes and improving oocyte quality for improved success of assistant reproductive technology (ART). The methods include the use of tunneling nanotube-forming cells and oocytes, wherein the tunneling nanotube-forming cells transfer autologous genomic materials, biomolecules and cellular components to the oocytes. The devices of the invention include microfluidic device to improve the efficiency of the transfer of biomolecules and cellular components between tunneling nanotube-forming cells and oocytes.
    Type: Grant
    Filed: January 26, 2021
    Date of Patent: December 26, 2023
    Assignee: The Chinese University of Hong Kong
    Inventors: Tin Lap Lee, Tin Chiu Li, Yiu Leung Chan, Wing Tung Lee, Kin Wing Judy Ng, Ting Hei Thomas Chan
  • USE OF PERIPHERAL BLOOD PRO- AND ANTI-INFLAMMATORY CYTOKINE RATIOS AS MARKERS OF IMPLANTATION PRECEDING PREGNANCY
    Publication number: 20220082572
    Abstract: The subject invention pertains to systems and methods diagnosing, monitoring and treating women for successful embryo implantation and establishment of pregnancy using peripheral blood cytokine profiling and administration of immune-modulators to establish an implantation-promoting microenvironment in the uterus.
    Type: Application
    Filed: September 17, 2020
    Publication date: March 17, 2022
    Inventors: Tin Chiu LI, Chi Chiu WANG, Tao ZHANG, Yiwei ZHAO, Xiaoyan CHEN
  • Method and apparatus for segmenting cellular image
    Patent number: 11210494
    Abstract: Method and apparatus for segmenting a cellular image are disclosed. A specific embodiment of the method includes: acquiring a cellular image; enhancing the cellular image using a generative adversarial network to obtain an enhanced cellular image; and segmenting the enhanced cellular image using a hierarchical fully convolutional network for image segmentation to obtain cytoplasm and zona pellucida areas in the cellular image.
    Type: Grant
    Filed: October 22, 2019
    Date of Patent: December 28, 2021
    Assignee: The Chinese University of Hong Kong
    Inventors: Yiu Leung Chan, Mingpeng Zhao, Han Hui Li, Tin Chiu Li
  • METHODS AND DEVICES FOR THE GENERATION OF OOCYTES WITH IMPROVED OOCYTE QUALITY FOR IN VITRO FERTILIZATION PROCEDURES USING NON-INVASIVE CELLULAR TRANSFER
    Publication number: 20210238545
    Abstract: The subject invention pertains to methods and devices for generating mature oocytes from immature oocytes and improving oocyte quality for improved success of assistant reproductive technology (ART). The methods include the use of tunneling nanotube-forming cells and oocytes, wherein the tunneling nanotube-forming cells transfer autologous genomic materials, biomolecules and cellular components to the oocytes. The devices of the invention include microfluidic device to improve the efficiency of the transfer of biomolecules and cellular components between tunneling nanotube-forming cells and oocytes.
    Type: Application
    Filed: January 26, 2021
    Publication date: August 5, 2021
    Inventors: Tin Lap LEE, Tin Chiu LI, Yiu Leung CHAN, Wing Tung LEE, Kin Wing Judy NG, Ting Hei Thomas CHAN
  • METHOD AND APPARATUS FOR SEGMENTING CELLULAR IMAGE
    Publication number: 20200125818
    Abstract: Method and apparatus for segmenting a cellular image are disclosed. A specific embodiment of the method includes: acquiring a cellular image; enhancing the cellular image using a generative adversarial network to obtain an enhanced cellular image; and segmenting the enhanced cellular image using a hierarchical fully convolutional network for image segmentation to obtain cytoplasm and zona pellucida areas in the cellular image.
    Type: Application
    Filed: October 22, 2019
    Publication date: April 23, 2020
    Inventors: Yiu Leung CHAN, Mingpeng ZHAO, Han Hui LI, Tin Chiu LI