Patents by Inventor Tina BUCH

Tina BUCH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of manufacturing bispecific antibodies, bispecific antibodies and therapeutic use of such antibodies
    Patent number: 11987644
    Abstract: The invention relates to bivalent bispecific monoclonal antibodies (bbmAb) or variants thereof, and methods of manufacturing such antibodies by co-expressing modified Fc-mutated derivatives of two different monoclonal antibodies in mammalian cell lines.
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: May 21, 2024
    Assignee: NOVARTIS AG
    Inventors: Michael Otto Bardroff, Tina Buch, Christian Graf, Daniel Heitmann, Thomas Jostock, Hans-Peter Knopf, Rolf Koehler, Jiri Kovarik, Stephen John Oliver, Dhavalkumar Patel, Maximilian Woisetschlaeger
  • METHOD OF MANUFACTURING BISPECIFIC ANTIBODIES, BISPECIFIC ANTIBODIES AND THERAPEUTIC USE OF SUCH ANTIBODIES
    Publication number: 20200308309
    Abstract: The invention relates to bivalent bispecific monoclonal antibodies (bbmAb) or variants thereof, and methods of manufacturing such antibodies by co-expressing modified Fc-mutated derivatives of two different monoclonal antibodies in mammalian cell lines.
    Type: Application
    Filed: April 9, 2020
    Publication date: October 1, 2020
    Inventors: Michael Otto BARDROFF, Tina BUCH, Christian GRAF, Daniel HEITMANN, Thomas JOSTOCK, Hans-Peter KNOPF, Rolf KOEHLER, Jiri KOVARIK, Stephen John OLIVER, Dhavalkumar PATEL, Maximilian WOISETSCHLAEGER
  • METHOD OF MANUFACTURING BISPECIFIC ANTIBODIES, BISPECIFIC ANTIBODIES AND THERAPEUTIC USE OF SUCH ANTIBODIES
    Publication number: 20190002589
    Abstract: The invention relates to bivalent bispecific monoclonal antibodies (bbmAb) or variants thereof, and methods of manufacturing such antibodies by co-expressing modified Fc-mutated derivatives of two different monoclonal antibodies in mammalian cell lines.
    Type: Application
    Filed: June 11, 2018
    Publication date: January 3, 2019
    Applicant: NOVARTIS AG
    Inventors: Michael Otto BARDROFF, Tina BUCH, Christian GRAF, Daniel HEITMANN, Thomas JOSTOCK, Hans-Peter KNOPF, Rolf KOEHLER, Jiri KOVARIK, Stephen John OLIVER, Dhavalkumar PATEL, Maximilian WOISETSCHLAEGER