Abstract: The present disclosure relates to mobility management methods and apparatuses. In an example method, a first network device sends conditional handover configuration information of a terminal device to a second network device. After obtaining a mobility report, the first network device sends a first message to the second network device to request the conditional handover configuration information of the terminal device. The first network device receives a response message of the first message from the second network device.

Abstract: Provided are a genetically modified cell line producing a recombinant glycoprotein having a mannose-terminated N-glycan and a method for producing the recombinant glycoprotein or a method for generating the cell, clone or cell line. The cell line comprises an insertion of less than 600 bp in the coding region of a chromosomal sequence encoding MGAT1.

Abstract: A lacosamide pharmaceutical composition as well as a preparation method and application thereof are provided. According to the lacosamide pharmaceutical composition, lacosamide or a pharmaceutically acceptable salt thereof can be dissolved out at the same time, wherein the dissolution rate of the lacosamide pharmaceutical composition is not more than 40% within 1 hour, the dissolution rate of the lacosamide pharmaceutical composition is 20-70% within 6 hours, and the dissolution rate of the lacosamide pharmaceutical composition is not less than 65% within 24 hours. The lacosamide pharmaceutical composition has good slow release performance, the tablet size can be rapidly expanded in the in-vitro dissolution process, the expanded lacosamide pharmaceutical composition has good rigidity and elasticity and has a remarkable retention effect in the stomach, and the cumulative release rate within 24 hours can reach 80% or above.

Abstract: The present disclosure relates a method for reducing animal weight, comprising administering to a patient in need thereof a therapeutically or prophylactically effective amount of a mulberry extract. The mulberry extract comprises: 3% to 99% of an alkaloid, 0.2% to 70% of a polysaccharide, 0% to 50% of an amino acid, 0% to 10% of flavone, and 0% to 25% of other components. The mulberry extract of the present disclosure can be used for controlling weight gain, and has a good therapeutic effect on type 2 diabetes with obesity.

Abstract: A method for determining lower radius limit of movable throat of shale is provided, and it includes: performing a low-temperature nitrogen adsorption test on a target shale to obtain first pore radii; performing a high-pressure mercury injection test on the target shale to obtain second pore radii; performing a nuclear magnetic resonance test on the target shale to obtain third pore radii; obtaining a relationship diagram of distribution frequencies and pore radii according to three pore radii; distinguishing, according to the pore radii, relationship diagram data, and performing normalization processing to determining a relationship curve of normalized frequency data and the pore radii; and determining a lower radius limit of movable throat of shale according to relationship curve. A problem of describing characteristics of shale occurrence space with complex pore structures and strong heterogeneity is solved, the method is suitable for determining lower radius limit of movable throat of shale.

Abstract: A method for determining lower radius limit of movable throat of shale is provided, and it includes: performing a low-temperature nitrogen adsorption test on a target shale to obtain first pore radii; performing a high-pressure mercury injection test on the target shale to obtain second pore radii; performing a nuclear magnetic resonance test on the target shale to obtain third pore radii; obtaining a relationship diagram of distribution frequencies and pore radii according to three pore radii; distinguishing, according to the pore radii, relationship diagram data, and performing normalization processing to determining a relationship curve of normalized frequency data and the pore radii; and determining a lower radius limit of movable throat of shale according to relationship curve. A problem of describing characteristics of shale occurrence space with complex pore structures and strong heterogeneity is solved, the method is suitable for determining lower radius limit of movable throat of shale.

Abstract: Provided are an anti-CLDN6 antibody or an antigen-binding fragment thereof; a nucleic acid molecule encoding same; an immunoconjugate, a bispecific molecule, a chimeric antigen receptor and a pharmaceutical composition containing same; and the use thereof for preventing and/or treating tumors.

Abstract: The present application relates to novel compounds that have modulating or activating effect on the activity of adenosine A3 receptor, preparation methods for the series of compounds, pharmaceutical compositions of the series of compounds, and pharmaceutical uses of the series of compounds.

Abstract: A curling device and a flexible display device are provided. The curling device includes: the electromagnetic telescoping mechanism and the controller are in communication connection; the electromagnetic telescopic mechanism is configured to connect with the flexible display panel element and expanding under the action of the magnetic field when receiving a first signal of the controller so as to drive the flexible display panel element to expand; when a second signal of the controller is received, the flexible display panel element is curled, so that the flexible display panel element is driven to curl.

Abstract: Provided are high affinity Mycobacterium tuberculosis arabinomannan-specific antibodies and antigen-binding fragments thereof. Also provided are methods of use and devices employing such Mycobacterium tuberculosis arabinomannan-specific antibodies and antigen-binding fragments thereof.

Abstract: A method for screening pesticide residues in medicine food homology (MFH) characteristic agricultural products includes step 1, a liquid chromatography-mass spectrometry database of pesticides is constructed, standard solution are prepared for the pesticides and liquid chromatography and mass spectrometry are used to detect the standard solutions; step 2, a sample is processed and then is detected to obtain a liquid chromatography-mass spectrogram; step 3, the liquid chromatography-mass spectrogram obtained from step 2 and liquid chromatography-mass spectrograms in the liquid chromatography-mass spectrometry database obtained from step 1 are compared and analyzed individually.

Abstract: The present disclosure provides a preparation method for hydrothermal synthesis of fly ash silicate aggregate including: mixing sodium metasilicate, potassium hydroxide, and inorganic-organic hybrid excitation monomer as raw materials to obtain an inorganic-organic composite activator; preparing a silicate aggregate raw material, mixing measured fly ash, carbide slag, quicklime, and vitrified micro bubble by mass, adding the inorganic-organic composite activator and continue stirring to produce a mixture; forming a ball disc, wetting an expanded perlite that forms a core of the ball by spraying water, adding a prepared mixture, spraying water while adding, standing and curing, performing a maturation and activation treatment in an autoclave, undergoing a silicon calcium reaction for a hydrothermal synthesis to obtain the silicate aggregates.

Abstract: The present disclosure relates to a leather coating composition comprising or consisting of a hydrosilylation curable silicone elastomer composition designed to be used as a topcoat for a synthetic leather material, particularly a silicone-based synthetic leather composite material. A silicone coating as a topcoat for a synthetic leather material which is the cured product of the composition, methods of making the topcoat, synthetic leather material utilizing same and uses of the synthetic leather material products are also disclosed. The topcoat is designed to provide a highly crosslinked silicone matrix containing silicon-free organic micro-particles to minimize or at least decrease change in gloss after abrasion.

Abstract: Provided is a chimeric antigen receptor, comprising an antigen binding region, a transmembrane domain and an intracellular signaling region. The antigen binding region comprises an antibody specifically targeting CD7, and the intracellular signaling region consists of a co-stimulatory domain, a primary signal transduction domain, and a ?C chain or intracellular region thereof. Also provided are an engineered immune cell comprising the chimeric antigen receptor and a pharmaceutical composition thereof, and use of the engineered immune cell/pharmaceutical composition for treating cancers.

Abstract: Provided are high affinity Mycobacterium tuberculosis capsule-specific antibodies and fragments thereof, as well as methods of use and devices employing such antibodies and/or fragments.

Abstract: A composition comprising an isocyanate composition comprising a polyisocyanate and a specific thermally conductive filler composition (C) can further be part of a two-component curable composition comprising the isocyanate composition and a polyol composition and having a low viscosity upon admixing and upon cure provides a high thermal conductivity.

Abstract: Provided are high affinity Mycobacterium tuberculosis capsule-specific antibodies and fragments thereof, as well as methods of use and devices employing such antibodies and/or fragments.

Abstract: Embodiments of this application disclose a data processing method, and relate to the field of artificial intelligence. The method is applied to distributed parallel model training, for example, distributed training of a text translation model, a speech recognition model, a facial recognition model, a three-dimensional reconstruction model, and a virtual reality model. The method can implement hybrid parallelism in a distributed cluster. The method includes: inserting, based on tensor layouts of tensors of at least one operator in a deep neural network model, a redistribution operator between operators that have an input-output dependency relationship, to implement conversion between different tensor layouts; inserting the redistribution operator into a sliced computational graph; and determining an updated sliced computational graph to implement parallel model training of the deep neural network.

Abstract: A navigation satellite time system and its autonomous recovery method are provided, including a load time system, the load time system is configured to generate and maintain the load time, and the load time system comprises an space borne atomic clock, a time-frequency processing unit and a plurality of load time backups module, the time information of the load time is obtained from the ground station time; the pulse-per-second signals of the load time are generated and maintained by the space borne atomic clock and the time-frequency processing unit; when the time-frequency processing unit fails, the first-level recovery state is triggered: the time-frequency processing unit compares the time information and the pulse-per-second signals reversely output by the multiple load time backup modules to perform load time recovery.

Abstract: Provided is a medication decision support method and apparatus based on a graphics state machine. The method comprises the steps of: acquiring a medication consultation statement of a user; extracting a symptom information entity, an allergy information entity and an disease onset information entity in the medication consultation statement; forming a graphics state machine set with a high response speed to a target event; analyzing the disease degree information in the medication consultation statement of the user and an emotion word segmentation dictionary, and comparing the disease degree information with the disease degree information spoken to obtain a corrected value of the disease degree; removing excessive judgment or underestimated judgment, on the disease degree, and obtaining accurate disease degree information; and achieving medication decision support aiming at accurate disease degree information through the medication decision support device.