Patents by Inventor Titia Martine Truce Mulders

Titia Martine Truce Mulders has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150335464
    Abstract: An intrauterine system for the retention of a biologically active compound within the uterus of a female mammal is formed by a frame defining an interior space for receipt of a deposit of the compound. The frame has an open structure allowing access to a substantial part of an outer surface of the deposit and the deposit has a rate controlling structure that controls a rate of release of the compound within the uterus. Retention elements are provided on the frame for retaining the frame within the uterus.
    Type: Application
    Filed: August 3, 2015
    Publication date: November 26, 2015
    Inventors: Wouter de Graaff, Harm Veenstra, Titia Martine Truce Mulders
  • Publication number: 20140296833
    Abstract: An intrauterine system is disclosed for use in the treatment of dysfunctional uterine bleeding; menorraghia; dysmenorrhoea; endometriosis; uterine fibroids; climacteric complaints; osteoporosis; and urogenital atrophy. The system is formed by a frame defining an interior space for receipt of a deposit of a therapeutically effective dose of a biologically active compound. The frame has an open structure allowing access to a substantial part of an outer surface of the deposit, and the deposit has a rate controlling structure that controls a rate of release of the compound within the uterus. One or more retention elements are provided on the frame for retaining the frame within the uterus of a female mammal.
    Type: Application
    Filed: November 6, 2013
    Publication date: October 2, 2014
    Applicant: Merck Sharp & Dohme B.V.
    Inventors: Wouter de Graaff, Harm Veenstra, Titia Martine Truce Mulders
  • Patent number: 8568374
    Abstract: An intrauterine system is disclosed for use in the treatment of dysfunctional uterine bleeding; menorraghia; dysmenorrhoea; endometriosis; uterine fibroids; climacteric complaints; osteoporosis; and urogenital atrophy. The system is formed by a frame defining an interior space for receipt of a deposit of a therapeutically effective dose of a biologically active compound. The frame has an open structure allowing access to a substantial part of an outer surface of the deposit, and the deposit has a rate controlling structure that controls a rate of release of the compound within the uterus. One or more retention elements are provided on the frame for retaining the frame within the uterus of a female mammal.
    Type: Grant
    Filed: April 29, 2010
    Date of Patent: October 29, 2013
    Assignee: Merck Sharp & Dohme B.V.
    Inventors: Wouter De Graaff, Harm Veenstra, Titia Martine Truce Mulders
  • Publication number: 20130014763
    Abstract: An intrauterine system for the retention of a biologically active compound within the uterus of a female mammal is formed by a frame defining an interior space for receipt of a deposit of the compound. The frame has an open structure allowing access to a substantial part of an outer surface of the deposit and the deposit has a rate controlling structure that controls a rate of release of the compound within the uterus. Retention elements are provided on the frame for retaining the frame within the uterus.
    Type: Application
    Filed: September 18, 2012
    Publication date: January 17, 2013
    Applicant: MSD Oss B.V.
    Inventors: Wouter de Graaff, Harm Veenstra, Titia Martine Truce Mulders
  • Patent number: 8291910
    Abstract: An intrauterine system (1) for the retention of a biologically active compound within the uterus of a female mammal is formed by a frame (16) defining an interior space (20) for receipt of a deposit of the compound (22). The frame has an open structure (18) allowing access to a substantial part of an outer surface of the deposit and the deposit has a rate controlling structure that controls a rate of release of the compound within the Uterus. Retention elements (6) are provided on the frame for retaining the frame within the uterus.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: October 23, 2012
    Assignee: MSD Oss B.V.
    Inventors: Wouter de Graaff, Harm Veenstra, Titia Martine Truce Mulders
  • Publication number: 20110017219
    Abstract: An intrauterine system (1) for the retention of a biologically active compound within the uterus of a female mammal is formed by a frame (16) defining an interior space (20) for receipt of a deposit of the compound (22). The frame has an open structure (18) allowing access to a substantial part of an outer surface of the deposit and the deposit has a rate controlling structure that controls a rate of release of the compound within the Uterus. Retention elements (6) are provided on the frame for retaining the frame within the uterus.
    Type: Application
    Filed: November 7, 2008
    Publication date: January 27, 2011
    Inventors: Wouter de Graaff, Harm Veenstra, Titia Martine Truce Mulders
  • Publication number: 20100280464
    Abstract: An intrauterine system is disclosed for use in the treatment of dysfunctional uterine bleeding; menorraghia; dysmenorrhoea; endometriosis; uterine fibroids; climacteric complaints; osteoporosis; and urogenital atrophy. The system is formed by a frame defining an interior space for receipt of a deposit of a therapeutically effective dose of a biologically active compound. The frame has an open structure allowing access to a substantial part of an outer surface of the deposit, and the deposit has a rate controlling structure that controls a rate of release of the compound within the uterus. One or more retention elements are provided on the frame for retaining the frame within the uterus of a female mammal.
    Type: Application
    Filed: April 29, 2010
    Publication date: November 4, 2010
    Inventors: Wouter De Graaff, Harm Veenstra, Titia Martine Truce Mulders