Patents by Inventor Tivadar Tamas

Tivadar Tamas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLID STATE FORMS OF MIDOSTAURIN
    Publication number: 20200010481
    Abstract: The present disclosure relates to solid state forms of Midostaurin, processes for preparation thereof, pharmaceutical compositions thereof, and use thereof in the treatment of Acute Myelogenous Leukemia (AML) and Aggressive Systemic Mastocytosis. Chemical SHNCH formula: C35H30N4O4 Molecular mass: 570.
    Type: Application
    Filed: March 6, 2018
    Publication date: January 9, 2020
    Inventors: Zsuzsa Potarine Juhasz, Csilla Nemethe Racz, Szabolcs Struba, Renata Kertine Ferenczi, Tivadar Tamas
  • Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents
    Patent number: 8987263
    Abstract: Basic esters of fatty alcohols of the general formula: R1-O—CO-A or pharmaceutically acceptable salts thereof, wherein R1 is C12-C24 alkyl or C10-C24 alkenyl, and A is a residue containing at least one acyclic or cyclic amino group and/or at least one heteroaromatic ring containing a tertiary or quaternary nitrogen atom, are anti-inflammatory and immunomodulatory agents, useful in the treatment of immunologically-mediated inflammation, as adjuvants for antigens involved in both cellular and humoral responses.
    Type: Grant
    Filed: October 9, 2003
    Date of Patent: March 24, 2015
    Inventors: Meir Shinitzky, Irun R. Cohen, Raanan Margalit, Yaacov Herzig, Jeffrey Sterling, Gyorgy Toth, Istvan Miskolczi, Ferenc Rantal, Tivadar Tamas
  • Production of dolasetron
    Patent number: 7608714
    Abstract: The present invention provides an improved process for the preparation of Dolasetron salts, in particularly Dolasetron mesylate. Also provided are intermediates for the process and methods of preparing the intermediates.
    Type: Grant
    Filed: January 5, 2007
    Date of Patent: October 27, 2009
    Assignee: TEVA Gyógyszergyár Zártkörúen Müködö Részvénytársaság
    Inventors: Janos Hajko, Tivadar Tamas, Adrienne Kovacsne-Mezei, Erika Magyar Molnarne, Csaba Peto, Csaba Szabo
  • Dolasetron trifluoroacetate, polymorphs of dolasetron trifluoroacetate and process for preparation thereof
    Publication number: 20090062546
    Abstract: Provided are crystalline forms of dolasetron trifluoroacetate, methods for their preparation, and their use in preparing dolasetron mesylate.
    Type: Application
    Filed: July 21, 2008
    Publication date: March 5, 2009
    Inventors: Janos Hajko, Tivadar Tamas, Adrienne Kovacsne-Mezei, Piroska Kovacs
  • Polymorphs of Dolasetron base and process for preparation thereof
    Publication number: 20090030207
    Abstract: The present invention provides polymorphic forms of dolasetron base and methods for their use and preparation.
    Type: Application
    Filed: July 21, 2008
    Publication date: January 29, 2009
    Inventors: Janos Hajko, Tivadar Tamas, Adrienne Kovacsne-Mezei, Piroska Kovacs
  • Process for preparation of mycophenolate mofetil and other esters of mycophenolic acid
    Publication number: 20080280977
    Abstract: Provided are processes for the preparation of mycophenolate mofetil and other esters of mycophenolic acid.
    Type: Application
    Filed: July 18, 2008
    Publication date: November 13, 2008
    Inventors: Sandor Molnar, Csaba Szabo, Tivadar Tamas, Janos Hajko, Claude Singer, Beata Kosztya
  • Process for preparation of mycophenolate mofetil and other esters of mycophenolic acid
    Publication number: 20080281111
    Abstract: Provided are processes for the preparation of mycophenolate mofetil and other esters of mycophenolic acid.
    Type: Application
    Filed: July 18, 2008
    Publication date: November 13, 2008
    Inventors: Sandor Molnar, Csaba Szabo, Tivadar Tamas, Janos Hajko, Claude Singer, Beata Kosztya
  • Crystalline forms of Deferasirox
    Publication number: 20080262060
    Abstract: The present invention provides novel crystalline forms of deferasirox, methods for their production, and methods for conversion of the novel forms to the known crystalline form I.
    Type: Application
    Filed: January 29, 2008
    Publication date: October 23, 2008
    Inventors: Zoltan G. Toth, Tivadar Tamas, Csilla Nemethne Racz
  • Crystalline mycophenolate sodium
    Patent number: 7439373
    Abstract: Provided are crystalline mycophenolate sodium forms and processes for their preparation.
    Type: Grant
    Filed: July 20, 2005
    Date of Patent: October 21, 2008
    Assignee: TEVA Gyógyszergyár Zártkörúen Múködö Részvénytársaság
    Inventors: Sandor Molnar, Csaba Szabo, Tivadar Tamas, Janos Hajko, Adrienne Kovacsne-Mezei, Judith Aronhime
  • Mycophenolate mofetil impurity
    Publication number: 20080241948
    Abstract: Provided is an impurity of mycophenolate mofetil, processes for its preparation and its use as a reference.
    Type: Application
    Filed: March 31, 2008
    Publication date: October 2, 2008
    Inventors: Sandor Molnar, Tivadar Tamas, Janos Hajko, Beáta Kosztya, Amihai Eisenstadt
  • Processes for preparation of crystalline mycophenolate sodium
    Publication number: 20080103317
    Abstract: Provided are crystalline mycophenolate sodium forms and processes for their preparation.
    Type: Application
    Filed: December 14, 2007
    Publication date: May 1, 2008
    Inventors: Sandor Molnar, Csaba Szabo, Tivadar Tamas, Janos Hajko, Adrienne Kovacsne-Mezei, Judith Aronhime
  • Processes for preparation of crystalline mycophenolate sodium
    Publication number: 20080097096
    Abstract: Provided are crystalline mycophenolate sodium forms and processes for their preparation.
    Type: Application
    Filed: December 14, 2007
    Publication date: April 24, 2008
    Inventors: Sandor Molnar, Csaba Szabo, Tivadar Tamas, Janos Hajko, Adrienne Kovacsne-Mezei, Judith Aronhime
  • Mycophenolate mofetil impurity
    Patent number: 7358247
    Abstract: Provided is an impurity of mycophenolate mofetil, processes for its preparation and its use as a reference.
    Type: Grant
    Filed: April 26, 2005
    Date of Patent: April 15, 2008
    Assignee: TEVA Gyógyszergyár Zártköruen Muködö Részvénytársaság
    Inventors: Sandor Molnar, Tivadar Tamas, Janos Hajko, Beáta Kosztya, Amihai Eisenstadt
  • Crystalline forms of dolasetron base and processes for preparation thereof
    Publication number: 20070203176
    Abstract: The present invention provides crystalline polymorphic forms of Dolasetron base. Also provided are methods of preparing the crystalline polymorphic forms of Dolasetron base.
    Type: Application
    Filed: January 5, 2007
    Publication date: August 30, 2007
    Inventors: Janos Hajko, Tivadar Tamas, Adrienne Kovacsne-Mezei, Erika Molnarne
  • Production of dolasetron
    Publication number: 20070203219
    Abstract: The present invention provides an improved process for the preparation of Dolasetron salts, in particularly Dolasetron mesylate. Also provided are intermediates for the process and methods of preparing the intermediates.
    Type: Application
    Filed: January 5, 2007
    Publication date: August 30, 2007
    Inventors: Janos Hajko, Tivadar Tamas, Adrienne Kovacsne-Mezei, Erika Molnarne, Csaba Peto, Csaba Szabo
  • Forms of dolasetron mesylate and processes for their preparation
    Publication number: 20070203177
    Abstract: The present invention provides crystalline polymorphic forms of Dolasetron mesylate. Also provided are methods of preparing the crystalline polymorphic forms of Dolasetron mesylate. Further, the crystalline Dolasetron mesylate forms may be used in pharmaceutical compositions.
    Type: Application
    Filed: January 5, 2007
    Publication date: August 30, 2007
    Inventors: Janos Hajko, Tivadar Tamas, Adrienne Kovacsne-Mezei, Erika Molnarne, Csaba Peto, Csaba Szabo
  • Productioin of dolasetron
    Publication number: 20070203175
    Abstract: The present invention provides an improved process for the preparation of Dolasetron salts, in particularly Dolasetron mesylate. Also provided are intermediates for the process and methods of preparing the intermediates. Intermediates for preparing Dolasetron according to the invention include 7-alkoxycarbonyl-9-(alkoxycarbonylmethyl)-3-trialkylsilyloxy-9-azabicyclo[3.3.1]nonane compounds (SAN compounds) and endo-9-alkoxycarbonyl-5-trialkylsilyloxy-8-azatricyclo[5.3.1.03,8]undecan-10-one compounds (SQO compounds).
    Type: Application
    Filed: January 5, 2007
    Publication date: August 30, 2007
    Inventors: Janos Hajko, Tivadar Tamas, Adrienne Kovacsne-Mezei, Erika Molnarne, Csaba Peto, Csaba Szabo
  • Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-YL)methyl]-4H-carbazol-4-one
    Publication number: 20060252942
    Abstract: A process for preparing ondansetron by transamination of an ondansetron structural analog that can be readily prepared conveniently by a Mannich reaction is provided. The process represents an improvement upon known procedures for making ondansetron by transamination because of its rapid rate, selectivity and the ease with which the product can be isolated from the reaction mixture.
    Type: Application
    Filed: July 7, 2006
    Publication date: November 9, 2006
    Inventors: Sandor Molnar, Csaba Szabo, Erzsebet Meszaros Sos, Szabolcs Salyi, Tivadar Tamas
  • Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-YL)methyl]-4H-carbazol-4-one
    Patent number: 7098345
    Abstract: A process for preparing ondansetron by transamination of an ondansetron structural analog that can be readily prepared conveniently by a Mannich reaction is provided. The process represents an improvement upon known procedures for making ondansetron by transamination because of its rapid rate, selectivity and the ease with which the product can be isolated from the reaction mixture.
    Type: Grant
    Filed: April 29, 2003
    Date of Patent: August 29, 2006
    Assignee: TEVA Gyógyszergyár Zárkörüen Müködö Részvénytársaság
    Inventors: Sandor Molnar, Csaba Szabo, Erzsebet Meszaros Sos, Szabolcs Salyi, Tivadar Tamas
  • Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents
    Publication number: 20060173053
    Abstract: Basic esters of fatty alcohols of the general formula: R1-O—CO-A or pharmaceutically acceptable salts thereof, wherein R1 is C12-C24 alkyl or C10-C24 alkenyl, and A is a residue containing at least one acyclic or cyclic amino group and/or at least one heteroaromatic ring containing a tertiary or quaternary nitrogen atom, are anti-inflammatory and immunomodulatory agents, useful in the treatment of immunologically-mediated inflammation, as adjuvants for antigens involved in both cellular and humoral responses.
    Type: Application
    Filed: December 19, 2005
    Publication date: August 3, 2006
    Inventors: Meir Shinitzky, Irun Cohen, Raanan Margalit, Yaacov Herzig, Jeffrey Sterling, Gyorgy Toth, Istvan Miskolczi, Ferenc Rantal, Tivadar Tamas