Patents by Inventor Tiziano Martinengo

Tiziano Martinengo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing uracil derivatives
    Patent number: 5286861
    Abstract: The present invention relates to a novel process for preparing uracil derivatives useful as intermediates in the synthesis of uridines having antiviral or antitumor activity or useful as coadjuvants in antiviral therapy, characterized by converting a compound of the formula II into its mesylate derivative of the formula III which is the reduced to give the desired compound of the formula I: ##STR1## in which R.sub.1 is H, halogen, alkyl, aryl or aralkyl.
    Type: Grant
    Filed: August 21, 1992
    Date of Patent: February 15, 1994
    Assignee: Farmitalia Carlo Erba S.r.l.
    Inventors: Angelo Bedeschi, Walter Cabri, Ilaria Candiani, Tiziano Martinengo
  • Process for the preparation of 4-demethoxydaunomycinone, the aglycone of 4-demethoxy-daunorubicin
    Patent number: 5015745
    Abstract: 4-Demethoxy-daunomycinone I: ##STR1## the known aglycone of 4-demethoxy-daunorubicin, is prepared by protecting the 13-keto group of 4-demethyl-daunomycinone, sulfonylating the 4-hydroxy group, reacting the sulfonylated compound with an amine, removing the amino protecting group from the resultant 4-demethyl-4-(protected amino)-13-dioxolanyl-daunomycinone, diazotizing the thus-freed 4-amino group and reducing under mild conditions the resulting diazonium compound.
    Type: Grant
    Filed: February 6, 1989
    Date of Patent: May 14, 1991
    Assignee: Farmitalia Carlo Erba S.r.l.
    Inventors: Silvia De Bernardinis, Walter Cabri, Tiziano Martinengo, Franco Francalanci