Patents by Inventor Tobias Kapferer

Tobias Kapferer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for early sacubitril intermediates
    Patent number: 10774036
    Abstract: The invention relates to a new enantioselective process for producing useful intermediates for the manufacture of NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a ?-amino-?-biphenyl-?-methylalkanoic acid, or acid ester, backbone.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: September 15, 2020
    Assignee: Novartis AG
    Inventors: Florian Karl Kleinbeck-Riniker, Tobias Kapferer, Hongyong Kim, Jie Ku, Kurt Laumen, Yunzhong Li, Wei Peng, Thomas Ruch, Thierry Schlama, Yao Yang
  • Chemical Process for Preparing Pyrimidine Derivatives and Intermediates Thereof
    Publication number: 20200039935
    Abstract: The present disclosure relates to a method of synthesizing 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-[2-(propane-2-sulfonyl)-phenyl]-pyrimidine-2,4-diamine (ceritinib) and/or intermediates thereof, their use as pharmaceuticals and pharmaceutical compositions and the use of intermediates for preparing ceritinib.
    Type: Application
    Filed: October 8, 2019
    Publication date: February 6, 2020
    Inventors: Mark Clinton Davis, Baoqing Gong, Denis Har, Tobias Kapferer, Xuchun Zheng
  • NEW PROCESS FOR EARLY SACUBITRIL INTERMEDIATES
    Publication number: 20190359554
    Abstract: The invention relates to a new enantioselective process for producing useful intermediates for the manufacture of NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a ?-amino-?-biphenyl-?-methylalkanoic acid, or acid ester, backbone.
    Type: Application
    Filed: December 20, 2017
    Publication date: November 28, 2019
    Inventors: Florian Karl KLEINBECK-RINIKER, Tobias KAPFERER, Hongyong KIM, Jie KU, Kurt LAUMEN, Yunzhong LI, Wei PENG, Thomas RUCH, Thierry SCHLAMA, Yao YANG
  • NEW PROCESS FOR EARLY SACUBITRIL INTERMEDIATES
    Publication number: 20190256454
    Abstract: The invention relates to a new enantioselective process for producing useful intermediates for the manufacture of NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a ?-amino-?-biphenyl-?-methylalkanoic acid, or acid ester, backbone.
    Type: Application
    Filed: June 30, 2017
    Publication date: August 22, 2019
    Inventors: Florian Karl KLEINBECK-RINIKER, Tobias KAPFERER
  • Chemical Process for Preparing Pyrimidine Derivatives and Intermediates Thereof
    Publication number: 20180057457
    Abstract: The present disclosure relates to a method of synthesizing 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-[2-(propane-2-sulfonyl)-phenyl]-pyrimidine-2,4-diamine (ceritinib) and/or intermediates thereof, their use as pharmaceuticals and pharmaceutical compositions and the use of intermediates for preparing ceritinib.
    Type: Application
    Filed: March 4, 2015
    Publication date: March 1, 2018
    Applicant: Novartis AG
    Inventors: Mark Clinton Davis, Baoqing Gong, Denis Har, Tobias Kapferer, Xuchun Zheng
  • Pesticidal arylpyrrolidines
    Patent number: 9375000
    Abstract: Arylpyrrolidines of Formula (I): wherein each substituent is as defined in the specification, and use thereof as pesticides and animal parasite-controlling agents.
    Type: Grant
    Filed: September 13, 2011
    Date of Patent: June 28, 2016
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Jun Mihara, Mamoru Hatazawa, Daiei Yamazaki, Hidetoshi Kishikawa, Kei Domon, Hidekazu Watanabe, Norio Sasaki, Tetsuya Murata, Koichi Araki, Eiichi Shimojo, Teruyuki Ichihara, Tadashi Ishikawa, Katsuhiko Shibuya, Ulrich Görgens, Peter Bruechner, Reiner Fischer, Johannes-Rudolf Jansen, Tobias Kapferer, Simon Maechling, Michael Maue, Arnd Voerste
  • Pesticidal arylpyrrolidines
    Patent number: 9206122
    Abstract: Arylpyrrolidines of formula (I): wherein each substituent is as defined in the specification, and use thereof as pesticides and animal parasite-controlling agents.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: December 8, 2015
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Reiner Fischer, Peter Bruechner, Tobias Kapferer, Kerstin Ilg, Ulrich Goergens, Arnd Voerste, Mamoru Hatazawa, Eiichi Shimojo
  • Insecticidal aromatic amides
    Patent number: 9204645
    Abstract: The invention relates to compounds of the general formulae (I) and (II) in which the radicals A1, A2, A3, A4, M1, M2, M3, Q, R1, T, W1 and W2 have the meaning given in the description and to the use of the compounds for controlling animal pests. The invention furthermore relates to processes and intermediates for preparing the compounds of formula (I).
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: December 8, 2015
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Michael Maue, Tobias Kapferer, Friedrich August Muehlthau, Olga Malsam
  • N-(3-carbamoylphenly)-1H-pyrazole-5-carboxamide derivatives and the use thereof for controlling animal pests
    Patent number: 9126945
    Abstract: The invention relates to compounds of the general formula (I) in which the radicals A1, A2, A3, A4, L, Q, R1, T and W have the meaning given in the description and to the use of the compounds for controlling animal pests. The invention furthermore relates to processes and intermediates for preparing the compounds of formula (I).
    Type: Grant
    Filed: March 12, 2012
    Date of Patent: September 8, 2015
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Michael Maue, Isabelle Adelt, Markus Heil, Peter Jeschke, Tobias Kapferer, Friedrich August Mühlthau, Alexander Sudau, Olga Malsam, Peter Lösel, Arnd Voerste, Ulrich Görgens
  • Indolecarboxamides and benzimidazolecarboxamides as insecticides and acaricides
    Patent number: 9107411
    Abstract: The present invention relates to compounds of the general formula (I) in which R1 to R6, A, Y, X, G, n and m are each as defined in the description—and to a process for preparation thereof and to the use thereof as insecticides and acaricides.
    Type: Grant
    Filed: March 5, 2012
    Date of Patent: August 18, 2015
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Markus Heil, Eike Kevin Heilmann, Graham Holmwood, Peter Jeschke, Michael Maue, Tobias Kapferer, Matthias Riedrich, Angela Becker, Olga Malsam, Peter Lösel, Arnd Voerste, Ulrich Görgens, Roland Andree
  • Novel halogen-substituted compounds
    Publication number: 20150099766
    Abstract: The invention relates to compounds of the general formula (I), in which the radicals A1, A2, A3, A4, Lm, Q, R1, T and U have the meaning given in the description and to the use of the compounds for controlling animal pests. In addition, the invention relates to processes and intermediates for the preparation of the compounds according to formula (I).
    Type: Application
    Filed: December 15, 2014
    Publication date: April 9, 2015
    Inventors: Michael MAUE, Isabelle ADELT, Wolfgang GIENCKE, Markus HEIL, Peter JESCHKE, Bernd-Wieland KRÜGER, Friedrich August MÜHLTHAU, Alexander SUDAU, Klaus RAMING, Ulrich EBBINGHAUS-KINTSCHER, Martin ADAMCZEWSKI, Arnd VOERSTE, Ulrich GÖRGENS, Tobias KAPFERER, Mark Wilhelm DREWES, Angela BECKER, Eva-Maria FRANKEN
  • Halogen-substituted compounds
    Patent number: 8946234
    Abstract: The invention relates to compounds of the general formula (I), in which the radicals A1, A2, A3, A4, Lm, Q, R1, T and U have the meaning given in the description and to the use of the compounds for controlling animal pests. In addition, the invention relates to processes and intermediates for the preparation of the compounds according to formula (I).
    Type: Grant
    Filed: October 27, 2009
    Date of Patent: February 3, 2015
    Assignee: Bayer CropScience AG
    Inventors: Michael Maue, Isabelle Adelt, Wolfgang Giencke, Markus Heil, Peter Jeschke, Bernd-Wieland Krüger, Friedrich August Mühlthau, Alexander Sudau, Klaus Raming, Ulrich Ebbinghaus-Kintscher, Martin Adamczewski, Arnd Voerste, Ulrich Görgens, Tobias Kapferer, Mark Wilhelm Drewes, Angela Becker, Eva-Maria Franken
  • PESTICIDAL ARYLPYRROLIDINES
    Publication number: 20150025253
    Abstract: Arylpyrrolidines of formula (I): wherein each substituent is as defined in the specification, and use thereof as pesticides and animal parasite-controlling agents.
    Type: Application
    Filed: March 12, 2013
    Publication date: January 22, 2015
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Reiner Fischer, Peter Bruechner, Tobias Kapferer, Kerstin Ilg, Ulrich Goergens, Arnd Voerste, Mamoru Hatazawa, Eiichi Shimojo
  • NOVEL INSECTICIDAL AROMATIC AMIDES
    Publication number: 20140371240
    Abstract: The invention relates to compounds of the general formulae (I) and (II) in which the radicals A1, A2, A3, A4, M1, M2, M3, Q, R1, T, W1 and W2 have the meaning given in the description and to the use of the compounds for controlling animal pests. The invention furthermore relates to processes and intermediates for preparing the compounds of formula (I).
    Type: Application
    Filed: December 17, 2012
    Publication date: December 18, 2014
    Inventors: Michael Maue, Tobias Kapferer, Friedrich August Muehlthau, Olga Malsam
  • Haloalky-substituted amides as insecticides and acaricides
    Patent number: 8889878
    Abstract: The present invention relates to halogen-substituted amide derivatives of the general formula (I) in which R1 to R6, Q1 to Q8, A, V, W, X, Y, n and m are each defined as described in the description—and to a process for preparation thereof and to the use thereof as insecticides and acaricides.
    Type: Grant
    Filed: October 27, 2010
    Date of Patent: November 18, 2014
    Assignee: Bayer CropScience AG
    Inventors: Markus Heil, Eike Kevin Heilmann, Alexander Sudau, Tobias Kapferer, Friedrich August Mühlthau, Peter Jeschke, Arnd Voerste, Ulrich Görgens, Klaus Raming, Ulrich Ebbinghaus-Kintscher, Mark Drewes, Martin Adamczewski, Angela Becker
  • Haloalky -substituted amides as insecticides and acaricides
    Patent number: 8710242
    Abstract: The present invention relates to halogen-substituted amide derivatives of the general formula (I) in which R1 to R6, Q1 to Q8, A, V, W, X, Y, n and m are each defined as described in the description—and to a process for preparation thereof and to the use thereof as insecticides and acaricides.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: April 29, 2014
    Assignee: Bayer CropScience AG
    Inventors: Markus Heil, Eike Kevin Heilmann, Alexander Sudau, Tobias Kapferer, Friedrich August Mühlthau, Peter Jeschke, Arnd Voerste, Ulrich Görgens, Klaus Raming, Ulrich Ebbinghaus-Kintscher, Mark Drewes, Martin Adamczewski, Angela Becker
  • N-(3-CARBAMOYLPHENLY)-1H-PYRAZOLE-5-CARBOXAMIDE DERIVATIVES AND THE USE THEREOF FOR CONTROLLING ANIMAL PESTS
    Publication number: 20140088153
    Abstract: The invention relates to compounds of the general formula (I) in which the radicals A1, A2, A3, A4, L, Q, R1, T and W have the meaning given in the description and to the use of the compounds for controlling animal pests. The invention furthermore relates to processes and intermediates for preparing the compounds of formula (I).
    Type: Application
    Filed: March 12, 2012
    Publication date: March 27, 2014
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Michael Maue, Isabelle Adelt, Markus Heil, Peter Jeschke, Tobias Kapferer, Friedrich August Muehlthau, Alexander Sudau, Olga Malsam, Peter Loesel, Arnd Voerste, Ulrich Goergens
  • INDOLECARBOXAMIDES AND BENZIMIDAZOLECARBOXAMIDES AS INSECTICIDES AND ACARICIDES
    Publication number: 20140088167
    Abstract: The present invention relates to compounds of the general formula (I) in which R1 to R6, A, Y, X, G, n and m are each as defined in the description—and to a process for preparation thereof and to the use thereof as insecticides and acaricides.
    Type: Application
    Filed: March 5, 2012
    Publication date: March 27, 2014
    Applicant: Bayer Intellectual Property GmbH
    Inventors: Markus Heil, Eike Kevin Heilmann, Graham Holmwood, Peter Jeschke, Michael Maue, Tobias Kapferer, Matthias Reidrich, Angela Becker, Olga Malsam, Peter Losel, Arnd Voerste, Ulrich Görgens, Roland Andree
  • PESTICIDAL ARYLPYRROLIDINES
    Publication number: 20140046069
    Abstract: Arylpyrrolidines of Formula (I): wherein each substituent is as defined in the specification, and use thereof as pesticides and animal paracite-controlling agents.
    Type: Application
    Filed: September 13, 2011
    Publication date: February 13, 2014
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Jun Mihara, Mamoru Hatazawa, Daiei Yamazaki, Hidetoshi Kishikawa, Kei Domon, Hidekazu Watanabe, Norio Sasaki, Tetsuya Murata, Koichi Araki, Eiichi Shimojo, Teruyuki Ichihara, Tadashi Ishikawa, Katsuhiko Shibuya, Ulrich Goergens, Peter Bruechner, Reiner Fischer, Johannes-Rudolf Jansen, Tobias Kapferer, Simon Maechling, Michael Maue, Arnd Voerste
  • Haloalkyl-Substituted Amides as Insecticides and Acaricides
    Publication number: 20130172390
    Abstract: The present invention relates to halogen-substituted amide derivatives of the general formula (I) in which R1 to R6, Q1 to Q8, A, V, W, X, Y, n and m are each defined as described in the description—and to a process for preparation thereof and to the use thereof as insecticides and acaricides.
    Type: Application
    Filed: September 14, 2012
    Publication date: July 4, 2013
    Applicant: Bayer Intellectual Property GmbH
    Inventors: Markus Heil, Eike Kevin Heilmann, Alexander Sudau, Tobias Kapferer, Friedrich August Mühlthau, Peter Jeschke, Arnd Voerste, Ulrich Görgens, Klaus Raming, Ulrich Ebbinghaus-Kintscher, Mark Drewes, Martin Adamczewski, Angela Becker