Patents by Inventor Todd Jacobs
Todd Jacobs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11945863Abstract: The present invention relates to a nucleic acid molecule encoding a chain myeloid capable of specifically binding to CD33, CD16 and CD123, wherein said nucleic molecule comprises: (a) a nucleic add molecule encoding a protein represented by SEQ ID NO:1; (b) a nucleic acid molecule represented by SEQ ID NO:2; (c) the nucleic add molecule of (b), wherein each thymine is replaced by urea; (d) a nucleic acid molecule encoding a protein having at least 98% sequence identity to the protein of (a); or (e) a nucleic add molecule that is degenerate with respect to the nucleic acid molecule of (b) or (c). The present invention further relates to a vector comprising the nucleic acid molecule of the invention, a host cell transformed or transfected with the nucleic acid molecule or the vector of the invention, as well as to a method for the production of a single chain myeloid capable of specifically binding to CD33, CD16 and CD123.Type: GrantFiled: December 1, 2017Date of Patent: April 2, 2024Assignee: Friedrich-Alexander-Universität Erlangen-NürnbergInventors: Georg H. Fey, Todd Braciak, Claudia C. Roskopf, Ingo Schubert, Karl-Peter Hopfner, Nadja Fenn, Sarah Wildenhain, Uwe Jacob
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Patent number: 11840953Abstract: A selective catalytic reduction system control system (10) and method of its use include an ammonia (“NH3”) slip sensor (13) located within an interior space (27) of an exhaust stack (15) of a selective catalytic reactor (31), toward an inlet end (25) of the stack (15); a housing (17) located within the interior space of the exhaust stack; the housing including face panels 19; a nitrogen oxides (“NOx”) sensor (11) contained within an interior space (29) defined by the face panels of the housing, at least two of the face panels (19I, 19O) containing an oxidation catalyst; and a dosing controller (59) in communication with the NH3 and NOx sensors, the dosing controller including a microprocessor with dosing logic embedded thereon. The housing with oxidation catalyst acts as a linear box, isolating the NOx sensor from NH3 slip, linearizing the NOx sensor signal.Type: GrantFiled: February 20, 2023Date of Patent: December 12, 2023Assignee: Catalytic Combustion CorporationInventors: Daniel R. Piche, Benjamin R. Paffel, D. Todd Jacobs
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Patent number: 11759747Abstract: A diesel engine emissions catalyst which may be used to fill a niche between standard oxidation catalyst and diesel particulate filters for control of diesel particulate matter. The catalyst includes a structure (substrate) comprising one or more coated, corrugated micro-expanded metal foil layers. The coated surface may be a high surface area, stabilized, and promoted washcoat layer. The corrugated pattern may include a herringbone-style pattern that, when in use, is oriented in a longitudinal direction of the diesel engine exhaust flow. The micro-expanded metal foil provides small openings or eyes that, as the exhaust flow passes through the catalyst (transverse to the eye opening), particulates in the flow impinge on the surface and becomes trapped in the eyes. The catalyst may be used to treat a locomotive engine exhaust stream and may be used with a selective catalyst reduction system.Type: GrantFiled: June 6, 2022Date of Patent: September 19, 2023Assignee: Catalytic Combustion CorporationInventors: John W. Robinson, Jr., Donald R. Verdegan, D. Todd Jacobs
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Patent number: 11739673Abstract: A diesel-emissions reduction unit having an inlet adapted to receive an exhaust stream of the diesel engine; a diesel oxidation trap catalyst located adjacent the inlet; a dosing controller and an injection lance arranged to meter aqueous NH3 into the exhaust stream; a NOx concentration sensor and a NH3 concentration sensor with at least one oxidation catalyst panel arranged to isolate the NOx concentration sensor from NH3 in the exhaust stream; and an exhaust heater arranged to heat the exhaust stream of the diesel engine toward the inlet of the diesel emissions reduction unit.Type: GrantFiled: September 30, 2022Date of Patent: August 29, 2023Assignees: Catalytic Combustion Corporation, Knoxville Locomotive Works, Inc.Inventors: James M. Wurtz, Jr., Scott Gatewood, Michael Thomason, D. Todd Jacobs, Daniel R. Piche, Cody J. Molls, H. Peter Claussen, John W. Robinson, Jr.
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Publication number: 20230193804Abstract: A selective catalytic reduction system control system (10) and method of its use include an ammonia (“NH3”) slip sensor (13) located within an interior space (27) of an exhaust stack (15) of a selective catalytic reactor (31), toward an inlet end (25) of the stack (15); a housing (17) located within the interior space of the exhaust stack; the housing including face panels 19; a nitrogen oxides (“NOx”) sensor (11) contained within an interior space (29) defined by the face panels of the housing, at least two of the face panels (19I, 19O) containing an oxidation catalyst; and a dosing controller (59) in communication with the NH3 and NOx sensors, the dosing controller including a microprocessor with dosing logic embedded thereon. The housing with oxidation catalyst acts as a linear box, isolating the NOx sensor from NH3 slip, linearizing the NOx sensor signal.Type: ApplicationFiled: February 20, 2023Publication date: June 22, 2023Inventors: Daniel R. Piche, Benjamin R. Paffel, D. Todd Jacobs
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Patent number: 11585254Abstract: A selective catalytic reduction system control system (10) and method of its use include an ammonia (“NH3”) slip sensor (13) located within an interior space (27) of an exhaust stack (15) of a selective catalytic reactor (31), toward an inlet end (25) of the stack (15); a housing (17) located within the interior space of the exhaust stack; the housing including face panels 19; a nitrogen oxides (“NOx”) sensor (11) contained within an interior space (29) defined by the face panels of the housing, at least two of the face panels (19I, 19O) containing an oxidation catalyst; and a dosing controller (59) in communication with the NH3 and NOx sensors, the dosing controller including a microprocessor with dosing logic embedded thereon. The housing with oxidation catalyst acts as a linear box, isolating the NOx sensor from NH3 slip, linearizing the NOx sensor signal.Type: GrantFiled: February 14, 2022Date of Patent: February 21, 2023Assignee: Catalytic Combustion CorporationInventors: Daniel R. Piche, Benjamin R. Paffel, D. Todd Jacobs
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Publication number: 20230031827Abstract: A diesel-emissions reduction unit having an inlet adapted to receive an exhaust stream of the diesel engine; a diesel oxidation trap catalyst located adjacent the inlet; a dosing controller and an injection lance arranged to meter aqueous NH3 into the exhaust stream; a NOx concentration sensor and a NH3 concentration sensor with at least one oxidation catalyst panel arranged to isolate the NOx concentration sensor from NH3 in the exhaust stream; and an exhaust heater arranged to heat the exhaust stream of the diesel engine toward the inlet of the diesel emissions reduction unit.Type: ApplicationFiled: September 30, 2022Publication date: February 2, 2023Inventors: James M. Wurtz, JR., Scott Gatewood, Michael Thomason, D. Todd Jacobs, Daniel R. Piche, Cody J. Molls, H. Peter Claussen, John W. Robinson, JR.
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Patent number: 11499459Abstract: A diesel-electric locomotive includes a diesel emissions reduction unit, including an inlet configured to receive an exhaust stream of a high-speed diesel engine; means for trapping at least a portion of diesel particulate matter contained in the exhaust stream; an aqueous NH3 dosing system including a dosing controller in communication with an electronic locomotive controller and a nitrogen oxide (“NOx”) concentration sensor and an ammonia (“NH3”) concentration sensor, at least one oxidation catalyst panel arranged to isolate the NOx concentration sensor from NH3 in the exhaust stream; mixing elements located between the dosing system and the NOx and NH3 concentration sensors to mix metered aqueous NH3 in the exhaust stream; a selective catalyst reactor bed located between the mixing elements and the NOx and NH3 concentration sensors; and an exhaust heating system in communication with at least one of the dosing and electronic locomotive controllers.Type: GrantFiled: March 8, 2019Date of Patent: November 15, 2022Assignees: Catalytic Combustion Corporation, Knoxville Locomotive Works, Inc.Inventors: James M. Wurtz, Jr., Scott Gatewood, Michael Thomason, D. Todd Jacobs, Daniel R. Piche, Cody J. Molls, H. Peter Claussen, John W. Robinson, Jr.
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Publication number: 20220297063Abstract: A diesel engine emissions catalyst which may be used to fill a niche between standard oxidation catalyst and diesel particulate filters for control of diesel particulate matter. The catalyst includes a structure (substrate) comprising one or more coated, corrugated micro-expanded metal foil layers. The coated surface may be a high surface area, stabilized, and promoted washcoat layer. The corrugated pattern may include a herringbone-style pattern that, when in use, is oriented in a longitudinal direction of the diesel engine exhaust flow. The micro-expanded metal foil provides small openings or eyes that, as the exhaust flow passes through the catalyst (transverse to the eye opening), particulates in the flow impinge on the surface and becomes trapped in the eyes. The catalyst may be used to treat a locomotive engine exhaust stream and may be used with a selective catalyst reduction system.Type: ApplicationFiled: June 6, 2022Publication date: September 22, 2022Inventors: John W. Robinson, JR., Donald R. Verdegan, D. Todd Jacobs
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Publication number: 20220235683Abstract: A selective catalytic reduction system control system (10) and method of its use include an ammonia (“NH3”) slip sensor (13) located within an interior space (27) of an exhaust stack (15) of a selective catalytic reactor (31), toward an inlet end (25) of the stack (15); a housing (17) located within the interior space of the exhaust stack; the housing including face panels 19; a nitrogen oxides (“NOx”) sensor (11) contained within an interior space (29) defined by the face panels of the housing, at least two of the face panels (19I, 19O) containing an oxidation catalyst; and a dosing controller (59) in communication with the NH3 and NOx sensors, the dosing controller including a microprocessor with dosing logic embedded thereon. The housing with oxidation catalyst acts as a linear box, isolating the NOx sensor from NH3 slip, linearizing the NOx sensor signal.Type: ApplicationFiled: February 14, 2022Publication date: July 28, 2022Inventors: Daniel R. Piche, Benjamin R. Paffel, D. Todd Jacobs
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Patent number: 11351502Abstract: A diesel engine emissions catalyst which may be used to fill a niche between standard oxidation catalyst and diesel particulate filters for control of diesel particulate matter. The catalyst includes a structure (substrate) comprising one or more coated, corrugated micro-expanded metal foil layers. The coated surface may be a high surface area, stabilized, and promoted washcoat layer. The corrugated pattern may include a herringbone-style pattern that, when in use, is oriented in a longitudinal direction of the diesel engine exhaust flow. The micro-expanded metal foil provides small openings or eyes that, as the exhaust flow passes through the catalyst (transverse to the eye opening), particulates in the flow impinge on the surface and becomes trapped in the eyes. The catalyst may be used to treat a locomotive engine exhaust stream and may be used with a selective catalyst reduction system.Type: GrantFiled: January 14, 2019Date of Patent: June 7, 2022Assignee: Catalytic Combustion CorporationInventors: John W. Robinson, Jr., Donald R. Verdegan, D. Todd Jacobs
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Patent number: 11248509Abstract: A selective catalytic reduction system control system (10) and method of its use include an ammonia (“NH3”) slip sensor (13) located within an interior space (27) of an exhaust stack (15) of a selective catalytic reactor (31), toward an inlet end (25) of the stack (15); a housing (17) located within the interior space of the exhaust stack; the housing including face panels 19; a nitrogen oxides (“NOx”) sensor (11) contained within an interior space (29) defined by the face panels of the housing, at least two of the face panels (19I, 19O) containing an oxidation catalyst; and a dosing controller (59) in communication with the NH3 and NOx sensors, the dosing controller including a microprocessor with dosing logic embedded thereon. The housing with oxidation catalyst acts as a linear box, isolating the NOx sensor from NH3 slip, linearizing the NOx sensor signal.Type: GrantFiled: May 6, 2019Date of Patent: February 15, 2022Assignee: Catalytic Combustion CorporationInventors: Daniel R. Piche, Benjamin R. Paffel, D. Todd Jacobs
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Publication number: 20210322924Abstract: A diesel engine emissions catalyst which may be used to fill a niche between standard oxidation catalyst and diesel particulate filters for control of diesel particulate matter. The catalyst includes a structure (substrate) comprising one or more coated, corrugated micro-expanded metal foil layers. The coated surface may be a high surface area, stabilized, and promoted washcoat layer. The corrugated pattern may include a herringbone-style pattern that, when in use, is oriented in a longitudinal direction of the diesel engine exhaust flow. The micro-expanded metal foil provides small openings or eyes that, as the exhaust flow passes through the catalyst (transverse to the eye opening), particulates in the flow impinge on the surface and becomes trapped in the eyes. The catalyst may be used to treat a locomotive engine exhaust stream and may be used with a selective catalyst reduction system.Type: ApplicationFiled: January 14, 2019Publication date: October 21, 2021Inventors: Donald R. Verdegan, John W. Robinson, Jr., D. Todd Jacobs
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Publication number: 20210231039Abstract: A selective catalytic reduction system control system (10) and method of its use include an ammonia (“NH3”) slip sensor (13) located within an interior space (27) of an exhaust stack (15) of a selective catalytic reactor (31), toward an inlet end (25) of the stack (15); a housing (17) located within the interior space of the exhaust stack; the housing including face panels 19; a nitrogen oxides (“NOx”) sensor (11) contained within an interior space (29) defined by the face panels of the housing, at least two of the face panels (19I, 19O) containing an oxidation catalyst; and a dosing controller (59) in communication with the NH3 and NOx sensors, the dosing controller including a microprocessor with dosing logic embedded thereon. The housing with oxidation catalyst acts as a linear box, isolating the NOx sensor from NH3 slip, linearizing the NOx sensor signal.Type: ApplicationFiled: May 6, 2019Publication date: July 29, 2021Inventors: Daniel R. Piche, Benjamin R. Paffel, D. Todd Jacobs
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Publication number: 20210231042Abstract: A diesel-electric locomotive includes a diesel emissions reduction unit, including an inlet configured to receive an exhaust stream of a high-speed diesel engine; means for trapping at least a portion of diesel particulate matter contained in the exhaust stream; an aqueous NH3 dosing system including a dosing controller in communication with an electronic locomotive controller and a nitrogen oxide (“NOx”) concentration sensor and an ammonia (“NH3”) concentration sensor, at least one oxidation catalyst panel arranged to isolate the NOx concentration sensor from NH3 in the exhaust stream; mixing elements located between the dosing system and the NOx and NH3 concentration sensors to mix metered aqueous NH3 in the exhaust stream; a selective catalyst reactor bed located between the mixing elements and the NOx and NH3 concentration sensors; and an exhaust heating system in communication with at least one of the dosing and electronic locomotive controllers.Type: ApplicationFiled: March 8, 2019Publication date: July 29, 2021Inventors: James M. Wurtz, Jr., Scott Gatewood, Michael Thomason, D. Todd Jacobs, Daniel R. Piche, Cody J. Molls, H. Peter Claussen, John W. Robinson, Jr.
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Patent number: 6948637Abstract: An apparatus for discharging pressurized liquids at elevated positions includes a holding adapter, an actuating assembly, and an extension pole. The holding adapter includes first body member for holding a canister of pressurized liquid. The canister has an actuating stem extending from its top end thereof. An actuator nozzle is formed of an annular flange and a cap-like head portion. The head portion is disposed over the actuating stem. A handle portion is formed integrally with the first body member and extending downwardly from the holding adapter. The actuating assembly is telescoped over the canister and the holding adapter and includes a second body member for applying a downward force on the annular flange of the actuating nozzle to activate the actuating for discharging the pressurized liquid therefrom. The extension pole is operatively connected to a distal end of the handle portion and is adjustable to desired elevated positions.Type: GrantFiled: June 23, 2004Date of Patent: September 27, 2005Inventor: Todd Jacobs
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Publication number: 20050060202Abstract: The present invention presents a “serverless” medical information system network and method of creating one or more self-assembling and self-monitoring medical device network grids. Several communication node devices form each grid. Each node device may connect to one or more medical instruments, providing the medical instruments access to the network. The invention also includes methods for assembling the tree-like structure of the grid and balancing the load or placement of the nodes across the entire grid and for self-monitoring of the grid, such that the nodes can detect, record, and distribute changes to the status of any node in the grid. In addition, the nodes can provide web services to other computer devices, such as handheld devices.Type: ApplicationFiled: September 20, 2004Publication date: March 17, 2005Inventors: Richard Taylor, Todd Jacobs, Chandra Hays