Patents by Inventor Todor R. Khristov

Todor R. Khristov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • APPARATUS AND METHOD FOR IMMUNOMAGNETIC CELL SEPARATION
    Publication number: 20210261942
    Abstract: An apparatus and methods are provided for the magnetic separation of target bioentities. The apparatus includes a fluid chamber and a magnetic element for drawing target bioentities toward a collection surface of the fluid chamber. The apparatus may include a positioning assembly operable to variable change the position and orientation f the fluid chamber relative to the magnetic element.
    Type: Application
    Filed: May 10, 2021
    Publication date: August 26, 2021
    Inventors: Paul A. LIBERTI, Todor R. KHRISTOV, Dustin W. RITTER
  • SIMULTANEOUS SEPARATION AND ACTIVATION OF T CELLS FROM BLOOD PRODUCTS WITH SUBSEQUENT STIMULATION TO EXPAND T CELLS
    Publication number: 20200010826
    Abstract: Embodiments disclosed herein relate to methods for purifying, activating, and expanding T cells, and subsets thereof.
    Type: Application
    Filed: July 26, 2017
    Publication date: January 9, 2020
    Applicant: Biomagnetic Solutions LLC
    Inventors: Paul A. LIBERTI, Dustin W. RITTER, Todor R. KHRISTOV
  • APPARATUS AND METHOD FOR IMMUNOMAGNETIC CELL SEPARATION
    Publication number: 20180291364
    Abstract: An apparatus and methods are provided for the magnetic separation of target bioentities. The apparatus include a fluid chamber and a magnetic element for drawing target bioentities toward a collection surface of the fluid chamber. The apparatus may include a positioning assembly operable to variable change the position and orientation of the fluid chamber relative to the magnetic element.
    Type: Application
    Filed: May 9, 2016
    Publication date: October 11, 2018
    Inventors: Paul A. LIBERTI, Todor R. KHRISTOV, Dustin W. RITTER
  • COMMON CAPTURE CELL SEPARATIONS DONE VIA SIMULTANEOUS INCUBATION OF COMPONENTS
    Publication number: 20180038863
    Abstract: Methods are provided for the rapid and efficient separation of target bioentities.
    Type: Application
    Filed: February 25, 2016
    Publication date: February 8, 2018
    Inventors: Paul A. Liberti, Todor R. Khristov
  • MULTI-PARAMETER HIGH GRADIENT MAGNETIC SEPARATOR AND METHODS OF USE THEREOF
    Publication number: 20150153259
    Abstract: Disclosed is a high gradient magnetic separation apparatus for recovering magnetic ally labeled target entities from viscous and/or complex test media. The target entities are captured on a ferromagnetic element in which a magnetic field gradient is induced by a magnetic field source. The apparatus is designed to perform various operations on captured target entities. Methods of using the apparatus are also disclosed, e.g., for isolation of circulating tumor cells.
    Type: Application
    Filed: December 3, 2014
    Publication date: June 4, 2015
    Inventors: Paul A. Liberti, Jason R. Stephens, Todor R. Khristov, Theodore L. Liberti