Patents by Inventor Tohru Kayano

Tohru Kayano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibodies specific for human interferon-alpha subtype alpha 8
    Patent number: 8357782
    Abstract: The present invention has the first object to provide a monoclonal antibody specific to interferon ? subtype ?8 (IFN?8) and its mutant proteins, the second object to provide a hybridoma capable of producing the monoclonal antibody, the third object to provide a method for detecting the IFN?8 and its mutant proteins by the monoclonal antibody, the fourth object to provide a method for purifying the IFN?8 and its mutant proteins by the monoclonal antibody, and the fifth object to provide a therapeutic agent for treating diseases whose onsets or exacerbation are related with IFN?8.
    Type: Grant
    Filed: March 16, 2009
    Date of Patent: January 22, 2013
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Shigeharu Fukuda, Chie Ushio, Harumi Ariyasu, Tohru Kayano, Toshio Ariyasu, Tsunetaka Ohta
  • MONOCLONAL ANTIBODY SPECIFIC TO BOTH HUMAN INTERFERON-ALPHA SUBTYPE ALPHA 8 AND ITS MUTANT PROTEINS
    Publication number: 20110091968
    Abstract: The present invention has the first object to provide a monoclonal antibody specific to interferon ? subtype ?8 (IFN?8) and its mutant proteins, the second object to provide a hybridoma capable of producing the monoclonal antibody, the third object to provide a method for detecting the IFN?8 and its mutant proteins by the monoclonal antibody, the fourth object to provide a method for purifying the IFN?8 and its mutant proteins by the monoclonal antibody, and the fifth object to provide a therapeutic agent for treating diseases whose onsets or exacerbation are related with IFN?8.
    Type: Application
    Filed: March 16, 2009
    Publication date: April 21, 2011
    Inventors: Shigeharu Fukuda, Chie Ushio, Harumi Ariyasu, Tohru Kayano, Toshio Ariyasu, Tsunetaka Ohta
  • Antibody specific to interleukin 18 precursor
    Publication number: 20060073519
    Abstract: Disclosed are an antibody specific to interleukin 18 (IL-18) precursor, preparation processes therefor, and uses thereof. The antibody includes immunoglobulins in both forms of polyclonal and monoclonal antibodies which exhibits an immunoreactivity against IL-18 precursor at an intensity higher than against other substances. The antibody is useful in detection and purification of IL-18 precursor and in elimination and detoxification of the precursor accumulated in vivo. The detection method using the antibody is effective in qualitative and quantitative analyses for the precursor as well as in correction of imprecise results caused by assays using anti-IL-18 antibody which exhibits a cross reactivity against the precursor.
    Type: Application
    Filed: September 13, 2005
    Publication date: April 6, 2006
    Applicant: KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO
    Inventors: Tohru Kayano, Mutsuko Taniguchi, Hiroshi Yamauchi, Masashi Kurimoto