Patents by Inventor Tom Dudler

Tom Dudler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for inhibiting fibrosis in a subject in need thereof
    Patent number: 10736960
    Abstract: In one aspect, the invention provides methods for treating, inhibiting, alleviating or preventing fibrosis in a mammalian subject suffering, or at risk of developing a disease or disorder caused or exacerbated by fibrosis and/or inflammation. In one embodiment, the invention provides methods of treating a subject suffering from renal fibrosis. In one embodiment, the invention provides methods of reducing proteinuria in a subject suffering from a renal disease or condition associated with proteinuria. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation.
    Type: Grant
    Filed: January 5, 2017
    Date of Patent: August 11, 2020
    Assignees: Omeros Corporation, University of Leicester
    Inventors: Nigel John Brunskill, Gregory A. Demopulos, Tom Dudler, Hans-Wilhelm Schwaeble
  • METHODS FOR REDUCING PROTEINURIA IN A HUMAN SUBJECT SUFFERING FROM IMMUNOGLOBULIN A NEPHROPATHY
    Publication number: 20180105604
    Abstract: In one aspect, the invention provides methods for reducing proteinuria in a human subject suffering, or at risk of developing Immunoglobulin A Nephropathy (IgAN). The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory antibody effective to inhibit MASP-2-dependent complement activation.
    Type: Application
    Filed: October 12, 2017
    Publication date: April 19, 2018
    Inventors: Nigel John Brunskill, Gregory A. Demopulos, Tom Dudler, Hans-Wilhelm Schwaeble
  • Methods for Inhibiting Fibrosis in a Subject in Need Thereof
    Publication number: 20170189525
    Abstract: In one aspect, the invention provides methods for treating, inhibiting, alleviating or preventing fibrosis in a mammalian subject suffering, or at risk of developing a disease or disorder caused or exacerbated by fibrosis and/or inflammation. In one embodiment, the invention provides methods of treating a subject suffering from renal fibrosis. In one embodiment, the invention provides methods of reducing proteinuria in a subject suffering from a renal disease or condition associated with proteinuria. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation.
    Type: Application
    Filed: January 5, 2017
    Publication date: July 6, 2017
    Inventors: Nigel John Brunskill, Gregory A. Demopulos, Tom Dudler, Hans-Wilhelm Schwaeble