Patents by Inventor Tom Maria Deroo

Tom Maria Deroo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Influenza vaccine
    Patent number: 7468259
    Abstract: A method for manufacturing recombinant neuraminidase by culturing in a suitable culture medium host cells which are transformed with a neuraminidase expression vector or infected with a virus which is transformed with a neuraminidase expression vector, wherein the expression vector comprises at least a part of the coding region of a neuraminidase gene of an influenza virus minus the region which codes for the membrane anchor, or a modified version thereof, preceded in phase by a signal sequence; and isolating the expression product neuraminidase from the culture medium. The invention further relates to vectors expressing the neuraminidase.
    Type: Grant
    Filed: February 20, 2002
    Date of Patent: December 23, 2008
    Assignee: Vlaams Interuniversitair Instituut Voor Biotechnologie
    Inventors: Walter Charles Fiers, Tom Maria Deroo, Willy Alfons Min Jou
  • Recombinant oligometric protein complexes with enhanced immunogenic potential
    Patent number: 7449188
    Abstract: The present invention relates to a chimeric protein comprising an antigen and an oligomerisation domain. The present invention relates further to recombinant oligomeric protein complexes comprising said chimeric protein and the use thereof for the manufacture of a vaccine.
    Type: Grant
    Filed: January 18, 2002
    Date of Patent: November 11, 2008
    Assignee: Vlaams Interuniversitair Instituut Voor Biotechnologie
    Inventors: Marina De Filette, Tom Maria Deroo, Walter Fiers, Marleen Maras, Willy Alfons Min Jou
  • Recombinant oligomeric protein complexes with enhanced immunogenic potential
    Publication number: 20040116664
    Abstract: The present invention relates to a chimeric protein comprising an antigen and an oligomerisation domain. The present invention relates further to recombinant oligomeric protein complexes comprising said chimeric protein and the use thereof for the manufacture of a vaccine.
    Type: Application
    Filed: July 18, 2003
    Publication date: June 17, 2004
    Inventors: Marina De Filette, Tom Maria Deroo, Walter Fiers, Marleen Maras, Willy Alfons Min Jou
  • Influenza vaccine
    Patent number: 6605457
    Abstract: A recombinant neuraminidase obtainable by culturing in a suitable culture medium host cells which are transformed with a neuraminidase expression vector or infected with a virus which is transformed with a neuraminidase expression vector, wherein the expression vector comprises at least a part of the coding region of a neuraminidase gene of an influenze virus minus the region which codes for the membrane anchor, or a modified version thereof, preceded in phase by a signal sequence; and isolating the expression product neuraminidase from the culture medium. The invention further relates to a vaccine in which the recombinant neuraminidase is applied.
    Type: Grant
    Filed: February 25, 1999
    Date of Patent: August 12, 2003
    Assignee: Vlaams Interuniversitair Instituut Voor Biotechnologie
    Inventors: Walter Charles Fiers, Tom Maria Deroo, Willy Alfons Min Jou
  • Influenza vaccine
    Publication number: 20030129197
    Abstract: A method for manufacturing recombinant neuraminidase by culturing in a suitable culture medium host cells which are transformed with a neuraminidase expression vector or infected with a virus which is transformed with a neuraminidase expression vector, wherein the expression vector comprises at least a part of the coding region of a neuraminidase gene of an influenza virus minus the region which codes for the membrane anchor, or a modified version thereof, preceded in phase by a signal sequence; and isolating the expression product neuraminidase from the culture medium. The invention further relates to vectors expressing the neuraminidase.
    Type: Application
    Filed: February 20, 2002
    Publication date: July 10, 2003
    Applicant: VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE
    Inventors: Walter Charles Fiers, Tom Maria Deroo, Willy Alfons Min Jou