Abstract: Drip chambers are described herein. A drip chamber comprises an inlet, an outlet, and a chamber body. The chamber body defines a chamber volume in fluid communication with the inlet and the outlet. The chamber body is movable between a collapsed configuration having a first volume and an expanded configuration having a second volume. The second volume is larger than the first volume, and the chamber body is configured to be moved from the collapsed configuration to the expanded configuration to draw in a medical fluid from the inlet into the chamber volume to prime the drip chamber.

Abstract: Syringe assemblies are described herein. A syringe assembly includes an assembly housing, a first syringe, a second syringe, and a connecting gear. The first syringe is disposed within the assembly housing. Each plunger is movable within the respective syringe cavity and defines a respective chamber in the respective syringe cavity, wherein the respective chamber is in fluid communication with the respective syringe port, the respective plunger comprising a respective gear rack extending longitudinally along the respective plunger. The connecting gear is rotatably coupled to the assembly housing. The connecting gear is configured to be in meshed engagement with at least one of the first gear rack and the second gear rack of the syringes.

Abstract: A needleless connector may include a housing comprising a central longitudinal axis, a body portion, and a base portion. The body portion may include an inner surface forming an internal cavity, and a first port forming a first fluid passage to the internal cavity. The base portion may include a top section including a valve seal support, and a bottom section including a second port forming a second fluid passage to the internal cavity. The needleless connector may further include an asymmetrically-shaped valve disposed in the internal cavity. The asymmetrically-shaped valve may include a head portion, a valve body portion extending distally from the head portion, and a wall having an inner surface forming a valve cavity. The valve may be coupled with the housing such that the inner surface of the valve at the valve body portion is seated and radially supported on the valve seal support.

Abstract: Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a needle extending from a cartridge body and fluidly coupled to at least one of the controllable fluid pathways. A vial puck is provided for attachment to a vial to be fluidly coupled to the cartridge by the needle. The vial puck may include a hygroscopic member to absorb fluid from the needle to ensure a dry disconnect. A shuttle valve may also be provided.

Abstract: Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a needle extending from a cartridge body and fluidly coupled to at least one of the controllable fluid pathways. The cartridge includes a vacuum bellows that surrounds the needle when the bellows is in an extended configuration. The vacuum bellows is compressible to expose the needle and generates a vacuum condition within the bellows when the bellows is extended from a compressed configuration to the extended configuration. The needle may be a dual-lumen plastic needle.

Abstract: An exemplary syringe adapter for coupling with a syringe may include a housing. A needle-free connector may be disposed in the housing. A communication member may be in slidable engagement with the housing. The communication member may be slidable, with respect to the housing, between an unactuated state and an actuated state of the syringe adapter. A cannula may extend from the communication. In the unactuated state, the cannula may be retracted within the needle-free connector. In the actuated state, the cannula may protrude through and axially beyond the needle-free connector.

Abstract: Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a needle extending from a cartridge body and fluidly coupled to at least one of the controllable fluid pathways. A vial puck is provided for attachment to a vial to be fluidly coupled to the cartridge by the needle. The vial puck may include a hygroscopic member to absorb fluid from the needle to ensure a dry disconnect. A shuttle valve may also be provided.

Abstract: Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a needle extending from a cartridge body and fluidly coupled to at least one of the controllable fluid pathways. The cartridge includes a vacuum bellows that surrounds the needle when the bellows is in an extended configuration. The vacuum bellows is compressible to expose the needle and generates a vacuum condition within the bellows when the bellows is extended from a compressed configuration to the extended configuration. The needle may be a dual-lumen plastic needle.

Abstract: Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways, The cartridge includes a backpack for management of tubing to couple the cartridge to a receiving container. A disposable waste container is contained by the cartridge and the backpack. A syringe holder is provided for use of a syringe as a receiving container to receive a compounded medication.

Abstract: A needleless connector includes a housing having a central longitudinal axis, a body portion, and a base portion. The body portion includes an inner surface forming an internal cavity, and a first port forming a first fluid passage to the housing cavity. The base portion includes a top end section and a bottom end section. The top end section has a protrusion, and the bottom end portion has a second port forming a second fluid passage to the housing cavity. The needleless connector further includes a valve having a wall with an inner surface forming a valve cavity. The valve is coupled with the housing such that the protrusion is positioned in the valve cavity, and a proximal end of the protrusion is spaced apart from a proximal end of the valve cavity.

Abstract: An exemplary syringe adapter for coupling with a syringe may include a housing. A needle-free connector may be disposed in the housing. A communication member may be in slidable engagement with the housing. The communication member may be slidable, with respect to the housing, between an unactuated state and an actuated state of the syringe adapter. A cannula may extend from the communication. In the unactuated state, the cannula may be retracted within the needle-free connector. In the actuated state, the cannula may protrude through and axially beyond the needle-free connector.

Abstract: Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a needleless fluid port and a needleless vent port for fluid coupling to a vial via a vial puck. The vial puck includes corresponding needleless fluid and vent ports and a cannula. The cannula is extendible, by insertion of a protrusion on the cartridge into a shaft of the vial puck, into the vial to couple the vial to the needleless fluid and vent ports.

Abstract: Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes controllable fluid pathways. One or more rotary piston pump/valves may be used to move fluid and/or gasses through the various fluid pathways of the cartridge. For example, the cartridge may include a dedicated rotary piston pump/valve for each process that moves fluid and/or gas through the cartridge. When turning, the rotary piston pump/valve acts as a pump to move the fluid or gas, and when the rotary piston pump/valve stops turning, it effectively acts as a shutoff valve, preventing any fluid flow. Magnetic couplers for the cartridge may be provided on a pump head of the compounder system.

Abstract: Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a backpack for management of tubing to couple the cartridge to a receiving container. A disposable waste container is contained by the cartridge and the backpack. A syringe holder is provided for use of a syringe as a receiving container to receive a compounded medication.

Abstract: Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a needleless fluid port and a needleless vent port for fluid coupling to a vial via a vial puck. The vial puck includes corresponding needleless fluid and vent ports and a cannula. The cannula is extendible, by insertion of a protrusion on the cartridge into a shaft of the vial puck, into the vial to couple the vial to the needleless fluid and vent ports.

Abstract: Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes controllable fluid pathways. One or more rotary piston pump/valves may be used to move fluid and/or gasses through the various fluid pathways of the cartridge. For example, the cartridge may include a dedicated rotary piston pump/valve for each process that moves fluid and/or gas through the cartridge. When turning, the rotary piston pump/valve acts as a pump to move the fluid or gas, and when the rotary piston pump/valve stops turning, it effectively acts as a shutoff valve, preventing any fluid flow. Magnetic couplers for the cartridge may be provided on a pump head of the compounder system.

Abstract: Drip chambers are described herein. A drip chamber comprises an inlet, an outlet, and a chamber body. The chamber body defines a chamber volume in fluid communication with the inlet and the outlet. The chamber body is movable between a collapsed configuration having a first volume and an expanded configuration having a second volume. The second volume is larger than the first volume, and the chamber body is configured to be moved from the collapsed configuration to the expanded configuration to draw in a medical fluid from the inlet into the chamber volume to prime the drip chamber.

Abstract: A valve including an antimicrobial agent can be used with needleless access connectors. The valve can have an insert that includes an antimicrobial coating thereon and/or the valve can have physical features, such as a series of tunnels or groves or a patterned surface, containing an antimicrobial formulation and/or the valve can be made of a material that includes an antimicrobial agent.

Abstract: A needleless access connector having an access port and a sustained release antimicrobial coating only on a top surface of the access port is disclosed. The top surface of the access port can be defined by a top surface of a proximal end of a housing and a top surface of a head portion of a compressible valve disposed within an internal cavity of the housing. In certain embodiments of the present disclosure, the sustained release antimicrobial coating is on: (i) the top surface the proximal end of the housing, or (ii) the top surface of the head portion of the compressible valve, or (iii) the sustained release antimicrobial coating is only on both the top surface the proximal end of the housing and the top surface of the head portion of the compressible valve.

Abstract: Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. Dual-lumen tubing coupled to the cartridge at a first end includes a fluid line and a vent line attached, at a second end, to a connector for a receiving container for a compounded drug.