Abstract: Disclosed herein are methods and compositions for treatment of a microbiome associated disorder. Further, disclosed herein are methods and compositions for modulating short chain fatty acid production in a subject.

Abstract: Disclosed herein are methods and compositions for treatment of a microbiome associated disorder. Further, disclosed herein are methods and compositions for modulating short chain fatty acid production in a subject.

Abstract: Disclosed herein are methods and compositions for treatment of a microbiome associated disorder. Further, disclosed herein are methods and compositions for modulating short chain fatty acid production in a subject.

Abstract: The present disclosure provides a method for formulating a composition of isolated and purified microbes. The present disclosure provides methods for formulating a composition for administration to a subject in need thereof. The method can comprise obtaining a mixture that is substantially dry and comprises about 10% or less residual moisture. The mixture can comprise a population of isolated and purified microbes and a pharmaceutically acceptable carrier. The population can comprise one or more obligate anaerobes that are oxygen-stable. The methods can further comprise encapsulating said mixture in an enteric-coated capsule for delivery to said subject.

Abstract: The present disclosure provides methods of determining metabolic maps and identifying presence of and estimating abundances of microbiome metabolic pathways in an individual toward customized microbial therapy. In an aspect, the present disclosure provides a method of determining an abundance of a metabolic pathway from a sample comprising a population of a plurality of different organisms.

Abstract: A system may be provided for dynamically serving a content file with embedded content objects over the Internet to an end user system. A content object request function may receive a request for a webpage defined by the content file, the content file comprising embedded content objects. A content-file modifier may modify the content file to inject a reporting code that instructions to generate one or more reports comprising information relating to the content objects. A report receiver may receive the reports, the reports indicating where the content objects were rendered within the webpage. An object prioritizor may prioritize the content objects based on where the content objects were rendered. A delivery controller may adapt protocols for delivering the content objects to improve access to high-priority content objects.

Abstract: In some embodiments of the invention, a system for serving dynamic content objects is provided. The system includes a request fulfiller that: receives a request for a webpage from an end-user system, retrieves a content file associated with the requested webpage, and transmits a modified content file to the end-user system. The system further includes a content-file modifier that generates the modified content file, the content-file modifier including: a dynamic-code detector that detects that the retrieved content file comprises or is associated with a dynamic code; and a reporting-code injector that injects a reporting code into the retrieved content file or an associated content file to produce the modified content file, the reporting code including instructions to report data identifying usage characteristics of one or more content objects. A high-priority content object is identified based on the reported data, and access to the high-priority content object is improved.

Abstract: A system and method for accelerating web page delivery is disclosed in one embodiment. Web content requests are made to an edge server of a first point of presence (POP) of a content delivery network (CDN). The web content has embedded resource links. The first POP can rewrite the embedded resource links to route requests for the embedded resource links to any POP in the CDN or even the origin server. In some embodiments, the first POP can decide if the first POP and/or another POP referenced in a rewritten embedded resource link should cache and/or accelerate the resource referenced in the embedded resource link.

Abstract: A system and a method for accelerating delivery of a webpage by using a preloader file during a delay in fetching the web file are disclosed. When an end user makes a request through a client computer for a webpage, a Content Delivery Network (CDN) server sends the client a preloader file. The preloader file contains requests for resources that are likely to be part of the web file. The client downloads the resources, and the resources are saved in a browser cache. The preloader file also directs the client to request the webpage again. While the client is downloading the resources, the CDN server requests the web file from an origin server. The origin server composes the webpage and delivers the webpage to the CDN server. When the client makes a second request for the web file, the CDN server delivers the web file to the client. When the client renders the web file to display the webpage, the client can retrieve the resources from the browser cache.

Abstract: A system and method for accelerating web page delivery is disclosed in one embodiment. Web content requests are made to an edge server of a first point of presence (POP) of a content delivery network (CDN). The web content has embedded resource links. The first POP can rewrite the embedded resource links to route requests for the embedded resource links to any POP in the CDN or even the origin server. In some embodiments, the first POP can decide if the first POP and/or another POP referenced in a rewritten embedded resource link should cache and/or accelerate the resource referenced in the embedded resource link.

Abstract: A system and a method for accelerating delivery of a webpage by using a preloader file during a delay in fetching the web file are disclosed. When an end user makes a request through a client computer for a webpage, a Content Delivery Network (CDN) server sends the client a preloader file. The preloader file contains requests for resources that are likely to be part of the web file. The client downloads the resources, and the resources are saved in a browser cache. The preloader file also directs the client to request the webpage again. While the client is downloading the resources, the CDN server requests the web file from an origin server. The origin server composes the webpage and delivers the webpage to the CDN server. When the client makes a second request for the web file, the CDN server delivers the web file to the client. When the client renders the web file to display the webpage, the client can retrieve the resources from the browser cache.

Abstract: A system and method for accelerating web page delivery is disclosed in one embodiment. Web requests are made to an edge server of a first point of presence (POP) of a content delivery network (CDN). The web content can be cached at the edge server in the first POP. Where the cache is missing the web content, it is queried from a second POP determined to be closer to the origin server for the web content. The second POP can have its own cache or request the web content from the origin server. Only missing components from the web content are passed to the first POP. Additionally, the missing components can be compressed.

Abstract: In some embodiments of the invention, a system for serving dynamic content objects is provided. The system includes a request fulfiller that: receives a request for a webpage from an end-user system, retrieves a content file associated with the requested webpage, and transmits a modified content file to the end-user system. The system further includes a content-file modifier that generates the modified content file, the content-file modifier including: a dynamic-code detector that detects that the retrieved content file comprises or is associated with a dynamic code; and a reporting-code injector that injects a reporting code into the retrieved content file or an associated content file to produce the modified content file, the reporting code including instructions to report data identifying usage characteristics of one or more content objects. A high-priority content object is identified based on the reported data, and access to the high-priority content object is improved.

Abstract: A system may be provided for dynamically serving a content file with embedded content objects over the Internet to an end user system. A content object request function may receive a request for a webpage defined by the content file, the content file comprising embedded content objects. A content-file modifier may modify the content file to inject a reporting code that instructions to generate one or more reports comprising information relating to the content objects. A report receiver may receive the reports, the reports indicating where the content objects were rendered within the webpage. An object prioritizor may prioritize the content objects based on where the content objects were rendered. A delivery controller may adapt protocols for delivering the content objects to improve access to high-priority content objects.

Abstract: A system may be provided for dynamically serving a content file with embedded content objects over the Internet to an end user system. A content object request function may receive a request for a webpage defined by the content file, the content file comprising embedded content objects. A content-file modifier may modify the content file to inject a reporting code that instructions to generate one or more reports comprising information relating to the content objects. A report receiver may receive the reports, the reports indicating where the content objects were rendered within the webpage. An object prioritizor may prioritize the content objects based on where the content objects were rendered. A delivery controller may adapt protocols for delivering the content objects to improve access to high-priority content objects.

Abstract: A system and method for accelerating web page delivery is disclosed in one embodiment. Web content requests are made to an edge server of a first point of presence (POP) of a content delivery network (CDN). The web content has embedded resource links. The first POP can rewrite the embedded resource links to route requests for the embedded resource links to any POP in the CDN or even the origin server. In some embodiments, the first POP can decide if the first POP and/or another POP referenced in a rewritten embedded resource link should cache and/or accelerate the resource referenced in the embedded resource link.

Abstract: A system can be provided for dynamically serving a content file. A content object request function can receive a request for a webpage defined by the content file, the content file including a plurality of embedded or referenced content objects, at least one of the plurality of content objects including a Javascript. A content-file modifier can modify the content file to include instructions to generate reports comprising information relating to invocation of stubs. A report receiver can receive reports from the end user system, and an object usage analyzer quantifes usage of each of the stubs. An object prioritizor can prioritize the plurality of content objects based on the analysis, the prioritization including an identification of at least one high-priority content object. An object injector can modify the content file such that the high-priority content object automatically loads upon rendering of the content file.