Patents by Inventor Tomoaki Kuwaki

Tomoaki Kuwaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for selecting monoclonal antibodies for human G-CSF permitting low-level detection in human fluids
    Patent number: 5798274
    Abstract: The present invention relates to a high affinity monoclonal antibody for human G-CSF and to an enzyme immunoassay using said antibody. Specifically, the practice of the invention permits one skilled in the art to obtain monoclonal antibodies with the characteristics necessary to permit low-level detection of G-CSF in plasma of equal to or less than 0.5 pg/ml in an immunoassay without interference in human fluids.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 25, 1998
    Assignee: Kirin-Amgen, Inc.
    Inventors: Takanori Ichikawa, Tomoaki Kuwaki, Shigeru Matsuki, Katsumi Tachibana
  • Monoclonal antibodies and method for the determination of human G-CSF
    Patent number: 5468846
    Abstract: The present invention relates to a high affinity monoclonal antibody and to an enzyme immunoassay of human G-CSF using the antibody.The trace amount of human G-CSF in samples such as body fluids from patients with hematological disorders can be measured without interference in the body fluids. For example, the measurable human G-CSF concentration in plasma is 0.5 pg/ml in minimum.
    Type: Grant
    Filed: February 22, 1994
    Date of Patent: November 21, 1995
    Assignee: Kirin-Amgen Inc.
    Inventors: Takanori Ichikawa, Tomoaki Kuwaki, Shigeru Matsuki, Katsumi Tachibana