Abstract: It is an object of the invention to provide a method for rapid and accurate quantification of a sample in the human body of a patient. The invention relates to a method for quantification of the body internal concentration of a protein-based drug, comprising step A comprising using a sensing device mounted with a substance binding to a protein contained in the protein-based drug through a specific interaction to determine the binding mass per unit area of a solution containing the protein-based drug to the substance mounted on the sensing device as a standard value and step B comprising assaying a collected biological sample by the sensing device and comparing the resulting value with the standard value to determine the concentration of the protein-based drug contained in the biological sample. In such a manner, the blood concentration of a circulating protein-based drug can be quantified in patient bodies, to determine the optimal dose and enable an effective therapeutic treatment.

Abstract: An oscillator (2) capable of oscillating signals of specified frequencies in dipped state in liquid, comprising a diaphragm of piezoelectric material (9) having a front surface (9a), a rear surface (9b), and a side surface (9c), a first electrode (10A) installed on the front surface (9a) of the diaphragm (9), a second electrode (10B) installed on the rear surface of the diaphragm (9), and a covering material (6) for covering at least the rear surface (9b) side of the diaphragm (9), wherein an opening (14) is provided in the covering material (6), the first electrode (10A) comes into contact with the liquid with the oscillator (2) dipped in the liquid, gas is held in a space (23) formed of the rear surface (9b) and the covering material (6), and the opening (14) is allowed to communicate with the space (23), whereby, even if the liquid temperature varies, the oscillation frequencies can be stabilized in a rather short time.

Abstract: A mouse anti-human MP52 monoclonal antibody which binds to dimeric human MP52 but not to monomeric human MP52. This mouse monoclonal antibody comprising IgG and having a high specificity can be obtained by sensitizing mice with human MP52 (CHO-MP52) produced in CHO cells and human MP52 (rhMP52) produced in escherichia coli. This antibody is useful in, for example, purifying or assaying human MP52 produced b genetic engineering techniques.

Abstract: A device for forcing liquid into the wells of a multi-well plate, comprising a tank having an interior for holding a liquid, the tank including a bottom portion having multiple fine orifices spaced for registry with each of the multiple wells of the plate, a top portion opposite the bottom portion, and side portions connecting the top portion and the bottom portion, an inlet for supplying rinsing liquid to the interior of the tank, and a pushable surface portion selectively movable towards the interior of the tank for forcing rinsing liquid contained within the tank through the orifices.