Patents by Inventor Tomohiko Kawate

Tomohiko Kawate has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds for the treatment of mycobacterial infections
    Patent number: 10766872
    Abstract: The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof:
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: September 8, 2020
    Assignee: The Board Institute, Inc.
    Inventors: Deborah Hung, Sarah Stanley, Tomohiko Kawate, Noriakie Iwase, Motohisa Shimizu
  • COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS
    Publication number: 20200140425
    Abstract: Disclosed are compounds that can be used for treating tuberculosis.
    Type: Application
    Filed: April 10, 2019
    Publication date: May 7, 2020
    Inventors: Timothy A. Lewis, Sivaraman Dandapani, Deborah Hung, Benito Munoz, Partha Nag, Sarah Grant, Tomohiko Kawate
  • Compounds for the treatment of tuberculosis
    Patent number: 10301294
    Abstract: Disclosed are compounds that can be used for treating tuberculosis.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: May 28, 2019
    Assignees: THE BROAD INSTITUTE INC., MASSACHUSETTS GENERAL HOSPITAL, BRIGHAM AND WOMEN'S HOSPITAL
    Inventors: Timothy A. Lewis, Sivaraman Dandapani, Deborah Hung, Benito Munoz, Partha Nag, Sarah Grant, Tomohiko Kawate
  • Substituted aminothiazoles for the treatment of tuberculosis
    Patent number: 10221169
    Abstract: Disclosed ore substituted aminothiazoles, which can be used for, among other things, the treatment of tuberculosis, pharmaceutical compositions containing the same, and methods of using the same.
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: March 5, 2019
    Assignees: The Broad Institute, Inc., The General Hospital Corporation, The Brigham and Women's Hospital, Inc.
    Inventors: Deborah Hung, Michael Serrano-Wu, Sarah Grant, Tomohiko Kawate
  • COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS
    Publication number: 20170327481
    Abstract: The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof:
    Type: Application
    Filed: May 31, 2017
    Publication date: November 16, 2017
    Inventors: Deborah Hung, Sarah Stanley, Tomohiko Kawate, Noriakie Iwase, Motohisa Shimizu
  • SUBSTITUTED AMINOTHIAZOLES FOR THE TREATMENT OF TUBERCULOSIS
    Publication number: 20170305895
    Abstract: Disclosed ore substituted aminothiazoles, which can be used for, among other things, the treatment of tuberculosis, pharmaceutical compositions containing the same, and methods of using the same.
    Type: Application
    Filed: March 23, 2017
    Publication date: October 26, 2017
    Inventors: Deborah Hung, Michael Serrano-Wu, Sarah Grant, Tomohiko Kawate
  • Compounds for the treatment of mycobacterial infections
    Patent number: 9682064
    Abstract: The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof:
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: June 20, 2017
    Assignees: The Broad Institute, Inc., Massachusetts General Hospital
    Inventors: Deborah Hung, Sarah Stanley, Tomohiko Kawate, Noriakie Iwase, Motohisa Shimizu
  • COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS
    Publication number: 20170014378
    Abstract: The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof:
    Type: Application
    Filed: July 21, 2016
    Publication date: January 19, 2017
    Inventors: Deborah Hung, Sarah Stanley, Tomohiko Kawate, Noriakie Iwase, Motohisa Shimizu
  • Compounds for the treatment of mycobacterial infections
    Patent number: 9416121
    Abstract: The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof:
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: August 16, 2016
    Assignees: The Broad Institute, Inc., Massachusetts General Hospital
    Inventors: Deborah Hung, Sarah Stanley, Tomohiko Kawate, Noriakie Iwase, Motohisa Shimizu
  • COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS
    Publication number: 20160031870
    Abstract: Disclosed are compounds that can be used for treating tuberculosis.
    Type: Application
    Filed: March 12, 2014
    Publication date: February 4, 2016
    Inventors: Timothy A. Lewis, Sivaraman Dandapani, Deborah Hung, Benito Munoz, Partha Nag, Sarah Grant, Tomohiko Kawate
  • SUBSTITUTED AMINOTHIAZOLES FOR THE TREATMENT OF TUBERCULOSIS
    Publication number: 20160031874
    Abstract: Disclosed are substituted aminothiazoles, which can be used for, among other things, the treatment of tuberculosis, pharmaceutical compositions containing the same, and methods of using the same.
    Type: Application
    Filed: March 13, 2014
    Publication date: February 4, 2016
    Inventors: Deborah Hung, Michael Serrano-Wu, Sarah Grant, Tomohiko Kawate
  • COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS
    Publication number: 20140296232
    Abstract: The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof:
    Type: Application
    Filed: March 27, 2014
    Publication date: October 2, 2014
    Applicants: Massachusetts General Hospital, The Broad Institute, Inc.
    Inventors: Deborah Hung, Sarah Stanley, Tomohiko Kawate, Noriakie Iwase, Motohisa Shimizu
  • Base-modified nucleotides and their use for polymorphism detection
    Patent number: 6994998
    Abstract: The present invention relates to methods for the detection of polymorphisms by substituting a base-modified nucleotide for a natural nucleotide in a polynucleotide. The base-modified nucleotide renders the polynucleotide more susceptible to cleavage at the sites of its incorporation than site consisting of natural nucleotides. The fragments obtained are then analyzed to determine the presence or absence of a polymorphism.
    Type: Grant
    Filed: January 8, 2002
    Date of Patent: February 7, 2006
    Assignee: Sequenom, Inc.
    Inventors: Vincent P. Stanton, Jr., Jia Liu Wolfe, Tomohiko Kawate, Charles Allerson, Gregory L. Verdine
  • Method for identifying polymorphisms
    Publication number: 20050053972
    Abstract: The present invention relates to methods for the detection of polymorphism in polynucleotides by using hybridization of fragments of segments of a polynucleotide suspected of containing a polymorphism with an oligonucleotide having a sequence complementary to a fragment identifying the polymorphism and subsequent detection of incorporated labels in the oligonucleotide-fragment duplex.
    Type: Application
    Filed: May 4, 2004
    Publication date: March 10, 2005
    Inventors: Vince Stanton, Jia Wolfe, Tomohiko Kawate, Gregory Verdine, Jeffrey Olson
  • Fluorescence-based genotyping
    Patent number: 6855500
    Abstract: The present invention relates to a method for genotyping a diploid organism to detect single nucleotide polymorphisms (SNPs) using modified nucleotides or nucleotide residues substituted with fluorescent groups.
    Type: Grant
    Filed: March 26, 2002
    Date of Patent: February 15, 2005
    Assignee: Sequenom, Inc.
    Inventors: Jia Liu Wolfe, Tomohiko Kawate, Charles R. Allerson, Vincent P. Stanton, Jr.
  • Method for identifying polymorphisms
    Patent number: 6825009
    Abstract: The present invention relates to methods for the detection of polymorphism in polynucleotides by using hybridization of fragments of segments of a polynucleotide suspected of containing a polymorphism with an oligonucleotide having a sequence complementary to a fragment identifying the polymorphism and subsequent detection of incorporated labels in the oligonucleotide-fragment duplex.
    Type: Grant
    Filed: March 22, 2002
    Date of Patent: November 30, 2004
    Assignee: Variagenics, Inc.
    Inventors: Vince P. Stanton, Jr., Jia Liu Wolfe, Tomohiko Kawate, Gregory L. Verdine, Jeffrey Olson, Colin W Dykes
  • Fluorescence-based genotyping
    Publication number: 20030165880
    Abstract: The present invention relates to a method for genotyping a diploid organism to detect single nucleotide polymorphisms (SNPs) using modified nucleotides or nucleotide residues substituted with fluorescent groups.
    Type: Application
    Filed: March 26, 2002
    Publication date: September 4, 2003
    Inventors: Jia Liu Wolfe, Tomohiko Kawate, Charles R. Allerson, Vincent P. Stanton
  • Base-modified nucleotides and cleavage of polynucleotides incorporating them
    Patent number: 6610492
    Abstract: The present invention is directed to novel base-modified nucleotides and methods for their use in the preparation and cleavage of modified polynucleotides.
    Type: Grant
    Filed: January 8, 2002
    Date of Patent: August 26, 2003
    Assignee: Variagenics, Inc.
    Inventors: Vincent P. Stanton, Jr., Jia Liu Wolfe, Tomohiko Kawate, Charles Allerson, Gregory L. Verdine
  • Method for identifying polymorphisms
    Publication number: 20030134290
    Abstract: The present invention relates to methods for the detection of polymorphism in polynucleotides by using hybridization of fragments of segments of a polynucleotide suspected of containing a polymorphism with an oligonucleotide having a sequence complementary to a fragment identifying the polymorphism and subsequent detection of incorporated labels in the oligonucleotide-fragment duplex.
    Type: Application
    Filed: March 22, 2002
    Publication date: July 17, 2003
    Inventors: Vince P. Stanton, Jia Liu Wolfe, Tomohiko Kawate, Gregory L. Verdine, Jeffrey Olson
  • Compounds for the treatment of mycobacterial infections
    Patent number: RE48105
    Abstract: The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof:
    Type: Grant
    Filed: August 14, 2018
    Date of Patent: July 21, 2020
    Assignees: The Broad Institute, Inc., The General Hospital Corporation
    Inventors: Deborah Hung, Sarah Stanley, Tomohiko Kawate, Noriaki Iwase, Motohisa Shimizu