Abstract: There is provided with a method for treating cancer, comprising administering a pharmaceutical composition to a patient with cancer in combination with an anti-cancer agent, the pharmaceutical composition. A compound is represented by General Formula (I) or a pharmaceutically acceptable salt thereof: where R1 is an acyl residue from a fatty acid.

Abstract: A method for generating a medication regimen of a patient is disclosed. The method comprises receiving a plurality of prescriptions for the patient, wherein a prescription of the plurality of prescriptions indicates a medication and a frequency for administering a dose of the medication. The method further comprises mapping a plurality of doses of one or more medications to a prescription calendar based on the frequencies indicated in the plurality of prescriptions and determining a schedule for administering a plurality of doses of different medications corresponding to each prescription of the plurality of prescriptions based on the calendar and constraints regarding administering the plurality of doses.

Abstract: A hydrodynamic bearing device which can improve reliability by stabilizing a balance of dynamic pressures generated at a thrust bearing portion. The spindle motor 1 includes a hydrodynamic bearing device 4 including a shaft 41, a sleeve 42, first and second thrust flanges 41b and 41c, first and second thrust bearing portions 72 and 73 and thrust dynamic pressure generating grooves 72a and 73a. The thrust dynamic pressure generating grooves 72a and 73a are formed such that a plurality of groove portions are connected without being isolated from each other, and the groove depth becomes greater from the inner periphery toward the outer periphery.

Abstract: A flange on a shaft of a fluid dynamic bearing unit is to be provided with a hole connecting an outer periphery of the flange and an outer periphery of the shaft. A radial groove is provided on a surface of two flange half pieces, and a vertical groove communicating with the radial groove is provided on an inner circumferential surface of the flange half pieces. Upon combining the two flange half pieces with the grooves facing each other and attaching them to the shaft, a path connecting an outer periphery of the flange and an outer periphery of the shaft is formed. The groove may be formed in a desired cross-sectional shape such as a semicircle, triangle or rectangle. The groove may be formed only on either of the flange half pieces, and the groove can be formed by a simple process such as pressing.

Abstract: A hydrodynamic bearing device which can improve workability of injecting a lube repellant and effectively prevent leakage of a lubricant, a method for manufacturing the same, a spindle motor, and a recording and reproduction apparatus are provided. A hydrodynamic bearing device 4 includes a lube repellant 11a which is applied in a circular shape by a predetermined distance in a radial direction from a portion of an upper surface of a second thrust flange 41c where it is connected to a shaft 41 and a lube repellant 11b which is applied in a circular shape on an outer peripheral surface of the second thrust flange 41c below from an upper end in the radial direction by a predetermined distance. The lube repellant 11b is applied near the upper end portion in a gap formed between the outer peripheral surface of the second thrust flange 41c and an inner peripheral surface of an outer sleeve 44.

Abstract: A hydrodynamic bearing device which can improve workability of injecting a lube repellant and effectively prevent leakage of a lubricant, a method for manufacturing the same, a spindle motor, and a recording and reproduction apparatus are provided. A hydrodynamic bearing device 4 includes a lube repellant 11a which is applied in a circular shape by a predetermined distance in a radial direction from a portion of an upper surface of a second thrust flange 41c where it is connected to a shaft 41 and a lube repellant 11b which is applied in a circular shape on an outer peripheral surface of the second thrust flange 41c below from an upper end in the radial direction by a predetermined distance. The lube repellant 11b is applied near the upper end portion in a gap formed between the outer peripheral surface of the second thrust flange 41c and an inner peripheral surface of an outer sleeve 44.

Abstract: A fluid bearing device capable of preventing a lubricant from scattering outward even during rotation thereof, while holding a relatively large amount of lubricant at a seal surface portion. A lubricant is filled between a sleeve and a shaft, a seal surface portion is formed on the sleeve in a location facing an open end thereof, the seal surface portion has a sectional shape defined by a plurality of inclined surfaces, and an inclination angle ? of the inclined surface of the seal surface portion adjacent a radial bearing portion with respect to a shaft axis is formed to be larger than an inclination angle ? of the inclined surface of the seal surface portion distant away from the radial bearing portion with respect to the shaft axis.

Abstract: A hydrodynamic bearing device which can improve reliability by stabilizing a balance of dynamic pressures generated at a thrust bearing portion. The spindle motor 1 includes a hydrodynamic bearing device 4 including a shaft 41, a sleeve 42, first and second thrust flanges 41b and 41c, first and second thrust bearing portions 72 and 73 and thrust dynamic pressure generating grooves 72a and 73a. The thrust dynamic pressure generating grooves 72a and 73a are formed such that a plurality of groove portions are connected without being isolated from each other, and the groove depth becomes greater from the inner periphery toward the outer periphery.

Abstract: A fluid bearing device for preventing a lubricant from scattering outside even during rotation thereof, while holding a relatively large amount of lubricant in a seal surface portion. Lubricant is filled between a sleeve and a shaft, the seal surface portion is formed in a location facing an open end of the sleeve, a sectional shape of the seal surface portion is such that a smallest clearance from an outer peripheral surface of the shaft is at a radial bearing portion side end portion of the seal surface portion, a largest clearance is at an intermediate portion between the radial bearing portion side end portion and an open end side end portion of the seal surface portion, and a clearance at the open end side end portion of the seal surface portion is smaller than the clearance at the intermediate portion.

Abstract: A flange on a shaft of a fluid dynamic bearing unit is to be provided with a hole connecting an outer periphery of the flange and an outer periphery of the shaft. A radial groove is provided on a surface of two flange half pieces, and a vertical groove communicating with the radial groove is provided on an inner circumferential surface of the flange half pieces. Upon combining the two flange half pieces with the grooves facing each other and attaching them to the shaft, a path connecting an outer periphery of the flange and an outer periphery of the shaft is formed. The groove may be formed in a desired cross-sectional shape such as a semicircle, triangle or rectangle. The groove may be formed only on either of the flange half pieces, and the groove can be formed by a simple process such as pressing.

Abstract: A fluid bearing device for preventing a lubricant from scattering outside even during rotation thereof, while holding a relatively large amount of lubricant in a seal surface portion. Lubricant is filled between a sleeve and a shaft, the seal surface portion is formed in a location facing an open end of the sleeve, a sectional shape of the seal surface portion is such that a smallest clearance from an outer peripheral surface of the shaft is at a radial bearing portion side end portion of the seal surface portion, a largest clearance is at an intermediate portion between the radial bearing portion side end portion and an open end side end portion of the seal surface portion, and a clearance at the open end side end portion of the seal surface portion is smaller than the clearance at the intermediate portion.

Abstract: A fluid bearing device capable of preventing a lubricant from scattering outward even during rotation thereof, while holding a relatively large amount of lubricant at a seal surface portion. A lubricant is filled between a sleeve and a shaft, a seal surface portion is formed on the sleeve in a location facing an open end thereof, the seal surface portion has a sectional shape defined by a plurality of inclined surfaces, and an inclination angle ? of the inclined surface of the seal surface portion adjacent a radial bearing portion with respect to a shaft axis is formed to be larger than an inclination angle ? of the inclined surface of the seal surface portion distant away from the radial bearing portion with respect to the shaft axis.