Abstract: An object of the present invention is to provide a compound that has a specific chemical structure having an activation effect on SIRT6 and is useful as an active component for preventing and treating inflammatory diseases, and the present invention relates to a compound represented by Formula (1) or a pharmaceutically acceptable salt thereof, where each symbol in Formula (1) has the same definition as that described in the specification.

Abstract: A fine channel device capable of producing fine particles in an industrial scale, hardening the fine particles immediately after the production and recovering the fine particles from a medium without collapsing the shape of the produced fine particles, a fine particle producing method using the fine channel device and a solvent extraction method using the fine channel, are presented. The fine channel device comprises a fine channel provided with an inlet port and an inlet channel which feed a dispersion phase, an inlet port and an inlet channel which feed a continuous phase, and an outlet channel and an outlet port which discharge fine particles produced by the dispersion phase and the continuous phase, wherein the inlet channel for feeding the dispersion phase and the inlet channel for feeding the continuous phase are joined at an arbitrary angle, and the two inlet channels are connected to the outlet channel at the arbitrary angle.

Abstract: A fine channel device including a fine channel provided with at least two inlet ports for feeding fluid, inlet channels communicated with the inlet ports, a confluent portion communicated with the inlet channels, a branch portion communicated with the fine channel, from which at least two outlet channels are branched to feed predetermined amounts of fluid, and outlet ports communicated with the outlet channels. The fine channel is provided with a plurality of partition walls arranged along a boundary formed by at least two kinds of fluid fed from the inlet ports so as not to cause mutual contamination of fluid. Furthermore, the plurality of partition walls are spaced apart at intervals in a flowing direction of fluid.

Abstract: A fine channel device including a fine channel provided with at least two inlet ports for feeding fluid, inlet channels communicated with the inlet ports, a confluent portion communicated with the inlet channels, a branch portion communicated with the fine channel, from which at least two outlet channels are branched to feed predetermined amounts of fluid, and outlet ports communicated with the outlet channels. The fine channel is provided with a plurality of partition walls arranged along a boundary formed by at least two kinds of fluid fed from the inlet ports so as not to cause mutual contamination of fluid. Furthermore, the plurality of partition walls are spaced apart at intervals in a flowing direction of fluid.

Abstract: A fine channel device capable of producing fine particles in an industrial scale, hardening the fine particles immediately after the production and recovering the fine particles from a medium without collapsing the shape of the produced fine particles, a fine particle producing method using the fine channel device and a solvent extraction method using the fine channel, are presented. The fine channel device comprises a fine channel provided with an inlet port and an inlet channel which feed a dispersion phase, an inlet port and an inlet channel which feed a continuous phase, and an outlet channel and an outlet port which discharge fine particles produced by the dispersion phase and the continuous phase, wherein the inlet channel for feeding the dispersion phase and the inlet channel for feeding the continuous phase are joined at an arbitrary angle, and the two inlet channels are connected to the outlet channel at the arbitrary angle.

Abstract: A fine channel device capable of producing fine particles in an industrial scale, hardening the fine particles immediately after the production and recovering the fine particles from a medium without collapsing the shape of the produced fine particles, a fine particle producing method using the fine channel device and a solvent extraction method using the fine channel, are presented. The fine channel device comprises a fine channel provided with an inlet port and an inlet channel which feed a dispersion phase, an inlet port and an inlet channel which feed a continuous phase, and an outlet channel and an outlet port which discharge fine particles produced by the dispersion phase and the continuous phase, wherein the inlet channel for feeding the dispersion phase and the inlet channel for feeding the continuous phase are joined at an arbitrary angle, and the two inlet channels are connected to the outlet channel at the arbitrary angle.

Abstract: A fine channel device for performing a chemical treatment or for producing fine particles, capable of supplying a liquid to the fine channels evenly and producing products in a large quantity is provided. The fine channel device includes a storage space having a circular or polygonal recess for temporarily storing fluid, and supply channels formed in a radial direction from the storage space. A small chemical plant includes a plurality of the fine channel devices as fundamental constituents and a mechanism to supply at least one fluid and a mechanism to recover products produced.

Abstract: A fine channel device capable of producing fine particles in an industrial scale, hardening the fine particles immediately after the production and recovering the fine particles from a medium without collapsing the shape of the produced fine particles, a fine particle producing method using the fine channel device and a solvent extraction method using the fine channel, are presented. The fine channel device comprises a fine channel provided with an inlet port and an inlet channel which feed a dispersion phase, an inlet port and an inlet channel which feed a continuous phase, and an outlet channel and an outlet port which discharge fine particles produced by the dispersion phase and the continuous phase, wherein the inlet channel for feeding the dispersion phase and the inlet channel for feeding the continuous phase are joined at an arbitrary angle, and the two inlet channels are connected to the outlet channel at the arbitrary angle.

Abstract: A fine channel device comprising a fine channel (19) provided with at least two inlet ports (11, 28, 29) for feeding fluid, inlet channels communicated with the inlet ports, a confluent portion (37) communicated with the inlet channels to feed the fluid, a branch portion (4) communicated with the fine channel, from which at least two outlet channels are branched to feed predetermined amounts of fluid, and outlet ports (12, 30, 31) communicated with the outlet channels, wherein the fine channel (19) is provided with a plurality of partition walls (22) along a boundary formed by at least two kinds of fluid (13, 14) fed from the inlet ports so as not to cause mutual contamination of fluid, whereby different kinds of fluid flowing in the fine channel in an adjacent state can form stably the fluid boundary and each kind of fluid can be discharged from a predetermined outlet port separately without causing the mutual contamination of fluid between adjacent flows of the fluid, is provided.

Abstract: A fine channel device for performing a chemical treatment or for producing fine particles, having the degree of integration of fine particles two-dimensionally and three-dimensionally and capable of supplying a liquid to all of the fine channels evenly and producing products in a large quantity, is provided, and a small-sized chemical plant capable of achieving a production quantity comparable to a conventional large-scale chemical plant comprising the fine channel device as a fundamental constituent factor, is provided.

Abstract: A fine channel device capable of producing fine particles in an industrial scale, hardening the fine particles immediately after the production and recovering the fine particles from a medium without collapsing the shape of the produced fine particles, a fine particle producing method using the fine channel device and a solvent extraction method using the fine channel, are presented. The fine channel device comprises a fine channel provided with an inlet port and an inlet channel which feed a dispersion phase, an inlet port and an inlet channel which feed a continuous phase, and an outlet channel and an outlet port which discharge fine particles produced by the dispersion phase and the continuous phase, wherein the inlet channel for feeding the dispersion phase and the inlet channel for feeding the continuous phase are joined at an arbitrary angle, and the two inlet channels are connected to the outlet channel at the arbitrary angle.

Abstract: A method for fixing a full color toner image by inserting a transfer medium to which a toner image is transferred, between a pair of rolls of a fixing apparatus, and pressing the medium therebetween, wherein the toner image is formed of a full color toner prepared by dispersing a colorant into a polyester resin containing a diol component represented by the following general formula (I) as a constituent and having a softening point of 100.degree. to 120.degree. C., as measured by a ring and ball method, a glass transition temperature of 55.degree. C. or more, a Gardner color scale of 2 or less and a haze value of 15 or less, and the fixing operation is conducted while supplying a functional group-containing organopolysiloxane having a viscosity of 10 to 100,000 cs at 25.degree. C.