Patents by Inventor Tomohiro Seki

Tomohiro Seki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240140286
    Abstract: An air supply apparatus supplies air to an airbag of a seat includes a support panel and a functional component. A first direction is a thickness of the base, a second direction is orthogonal to the first direction, and a direction orthogonal to both the first direction and the second direction is a third direction. A first restriction wall and a second restriction wall extend from the base in the first direction, spaced at an interval in the second direction, and sandwich the functional component in the second direction. A coupling wall extends from the base in the first direction and couples the first restriction wall to the second restriction wall in the second direction. Two guide walls are spaced in the third direction and sandwich the functional component in the third direction. Pressing portions sandwich the functional component together with the coupling wall in the first direction.
    Type: Application
    Filed: October 10, 2023
    Publication date: May 2, 2024
    Applicant: AISIN CORPORATION
    Inventors: Satoshi MASUDA, Tomokazu SEKI, Tomohiro HORI, Reiji SUZUKI
  • Publication number: 20240066047
    Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.
    Type: Application
    Filed: May 1, 2023
    Publication date: February 29, 2024
    Inventors: MASATO YOSHIKAWA, MORIHISA SAITOH, TAISUKE KATO, YAYOI NAKAYAMA, TOMOHIRO SEKI, YASUO NAKAGAWA, YUSUKE TOMINARI, MASAKI SETO, YUSUKE SASAKI, MASANORI OKANIWA, TSUNEO ODA, AKITO SHIBUYA, KOSUKE HIDAKA, ZENYU SHIOKAWA, SHUMPEI MURATA, ATSUTOSHI OKABE, YOSHIHISA NAKADA, MICHIYO MOCHIZUKI, BRIAN SCOTT FREEZE, TAISUKE TAWARAISHI, YASUFUMI WADA, PAUL D. GREENSPAN
  • Publication number: 20230295628
    Abstract: Developed and provided is: a nucleic acid agent that is efficiently delivered to the central nervous system, to which drug delivery is inhibited by the blood brain barrier mechanism, and that provides an antisense effect to a target transcription product at the delivery site; and a composition containing such a nucleic acid agent. Provided is a double-stranded nucleic acid complex consisting of a first nucleic acid strand and a second nucleic acid strand that are annealed to each other; wherein the first nucleic acid strand hybridizes with part of a target transcription product and has an antisense effect on the target transcription product; and wherein the second nucleic acid strand includes a base sequence complementary to the first nucleic acid strand and is conjugated to a phosphatidylethanolamine or an analog thereof.
    Type: Application
    Filed: February 2, 2023
    Publication date: September 21, 2023
    Applicants: National University Corporation Tokyo Medical and Dental University, Takeda Pharmaceutical Company Limited
    Inventors: Takanori Yokota, Tetsuya Nagata, Hideki Furukawa, Yasuo Nakagawa, Takatoshi Yogo, Ryosuke Tokunoh, Shigekazu Sasaki, Kosuke Hidaka, Tomohiro Seki, Kenichi Miyata, Akio Uchida
  • Patent number: 11666594
    Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.
    Type: Grant
    Filed: October 7, 2020
    Date of Patent: June 6, 2023
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Masato Yoshikawa, Morihisa Saitoh, Taisuke Kato, Yayoi Nakayama, Tomohiro Seki, Yasuo Nakagawa, Yusuke Tominari, Masaki Seto, Yusuke Sasaki, Masanori Okaniwa, Tsuneo Oda, Akito Shibuya, Kosuke Hidaka, Zenyu Shiokawa, Shumpei Murata, Atsutoshi Okabe, Yoshihisa Nakada, Michiyo Mochizuki, Brian Scott Freeze, Taisuke Tawaraishi, Yasufumi Wada, Paul D. Greenspan
  • Patent number: 11597928
    Abstract: Developed and provided is: a nucleic acid agent that is efficiently delivered to the central nervous system, to which drug delivery is inhibited by the blood brain barrier mechanism, and that provides an antisense effect to a target transcription product at the delivery site; and a composition containing such a nucleic acid agent. Provided is a double-stranded nucleic acid complex consisting of a first nucleic acid strand and a second nucleic acid strand that are annealed to each other; wherein the first nucleic acid strand hybridizes with part of a target transcription product and has an antisense effect on the target transcription product; and wherein the second nucleic acid strand includes a base sequence complementary to the first nucleic acid strand and is conjugated to a phosphatidylethanolamine or an analog thereof.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: March 7, 2023
    Assignees: National University Corporation Tokyo Medical and Dental University, Takeda Pharmaceutical Company Limited
    Inventors: Takanori Yokota, Tetsuya Nagata, Hideki Furukawa, Yasuo Nakagawa, Takatoshi Yogo, Ryosuke Tokunoh, Shigekazu Sasaki, Kosuke Hidaka, Tomohiro Seki, Kenichi Miyata, Akio Uchida
  • Publication number: 20220370491
    Abstract: The object of the present invention is to provide a nucleic acid agent that is efficiently delivered to the nervous system, for example, the central nervous system to which drug delivery can be prevented by BBB, and produces an antisense effect on the target transcriptional product at the delivery site, and a composition comprising the same. In an embodiment, the present invention provides a double-stranded nucleic acid complex formed by annealing a first nucleic acid strand that hybridizes to a part of a target transcriptional product and has an antisense effect on the target transcriptional product, and a second nucleic acid strand that comprises a base sequence complementary to the first nucleic acid strand and is bound to a C22-35 alkyl group optionally substituted with a hydroxy group or an analog thereof.
    Type: Application
    Filed: September 16, 2020
    Publication date: November 24, 2022
    Applicants: National University Corporation Tokyo Medical and Dental University, Takeda Pharmaceutical Company Limited
    Inventors: Takanori Yokota, Testuya Nagata, Hideki Furukawa, Takatoshi Yogo, Yasuo Nakagawa, Shigekazu Sasaki, Ryosuke Tokunoh, Tomohiro Seki, Kosuke Hidaka, Fumiaki Kikuchi, Osamu Kubo, Takahito Kasahara, Takuto Kojima, Junsi Wang, Norihito Tokunaga
  • Patent number: 11081998
    Abstract: To provide a controller of rotary electric machine which can control voltage of each set of the winding appropriately within a range less than or equal to the DC power voltage, to the rotary electric machine which has plural sets of windings. A controller of rotary electric machine calculates, for each set, a required DC voltage which is a minimum DC power voltage required for applying a voltage according to the voltage command value to the winding, based on the voltage command value; calculates one common required DC voltage which is common to all sets, based on all sets of the required DC voltages; changes the common voltage control value so that the common required DC voltage-approaches the DC power voltage; and changes each set of the current command value based on the common voltage control value.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: August 3, 2021
    Assignee: Mitsubishi Electric Corporation
    Inventors: Tomohiro Seki, Ryo Nakamura, Yuya Hisano, Masahiro Iezawa
  • Publication number: 20210163934
    Abstract: The object of the present invention is to provide a nucleic acid agent that can be efficiently delivered to the nervous system, particularly the central nervous system to which the BBB mechanism prevents drug delivery, and can produce an antisense effect on a target transcriptional product at the delivered site, and a composition comprising the same. Provided is a double-stranded nucleic acid complex formed by annealing a first nucleic acid strand capable of hybridizing to part of a target transcriptional product, and has an antisense effect on the target transcriptional product, to a second nucleic acid strand comprising a base sequence complementary to the first nucleic acid strand, and is bound to tocopherol or an analog thereof, cholesterol or an analog thereof, or a substituted or unsubstituted C1-30 alkyl group, a substituted or unsubstituted C2-30 alkenyl group, or a substituted or unsubstituted C1-30 alkoxy group.
    Type: Application
    Filed: March 22, 2019
    Publication date: June 3, 2021
    Applicant: NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
    Inventors: Takanori YOKOTA, Tetsuya NAGATA, Hideki FURUKAWA, Yasuo NAKAGAWA, Takatoshi YOGO, Ryosuke TOKUNOH, Shigekazu SASAKI, Kosuke HIDAKA, Tomohiro SEKI, Kenichi MIYATA, Yusuke ADACHI, Naoto ARIMURA
  • Publication number: 20210137962
    Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.
    Type: Application
    Filed: November 9, 2018
    Publication date: May 13, 2021
    Inventors: Masato Yoshikawa, Morihisa Saitoh, Taisuke Kato, Yayoi Yoshitomi, Tomohiro Seki, Yasuo Nakagawa, Yusuke Tominari, Masaki Seto, Akito Shibuya, Kosuke Hidaka, Zenyu Shiokawa, Yoshihisa Nakada, Michiyo Mochizuki
  • Patent number: 10980825
    Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: April 20, 2021
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Masato Yoshikawa, Morihisa Saitoh, Taisuke Kato, Yayoi Nakayama, Tomohiro Seki, Yasuo Nakagawa, Yusuke Tominari, Masaki Seto, Akito Shibuya, Kosuke Hidaka, Zenyu Shiokawa, Yoshihisa Nakada, Michiyo Mochizuki
  • Publication number: 20210106607
    Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.
    Type: Application
    Filed: October 7, 2020
    Publication date: April 15, 2021
    Inventors: MASATO YOSHIKAWA, Morihisa Saitoh, Taisuke Kato, Yayoi Nakayama, Tomohiro Seki, Yasuo Nakagawa, Yusuke Tominari, Masaki Seto, Yusuke Sasaki, Masanori Okaniwa, Tsuneo Oda, Akito Shibuya, Kosuke Hidaka, Zenyu Shiokawa, Shumpei Murata, Atsutoshi Okabe, Yoshihisa Nakada, Michiyo Mochizuki, Brian Scott Freeze, Taisuke Tawaraishi, Yasufumi Wada, Paul D. Greenspan
  • Publication number: 20210061833
    Abstract: The lanthanoid compound according to the present invention is a compound represented by the following general formula Ln(R1xCp)2(A)y or the following general formula Sm(R2xCp)2(A)y. In Ln(R1xCp)2(A)y, Ln is Nd, Eu, Dy, Tm, or Yb, R1 is independently Me, Et, nPr, iPr, nBt, sBu, iBu, or tAm, Cp is cyclopentadienyl, A is a linear or cyclic hydrocarbon containing oxygen, sulfur, phosphorus, or nitrogen, x is an integer of 2 to 3, and y is 0 to 2. In Sm(R2xCp)2(A)y, R2 is independently nPr, iPr, nBt, sBu, iBu, or tAm.
    Type: Application
    Filed: January 22, 2019
    Publication date: March 4, 2021
    Inventors: Christian DUSSARRAT, Takashi ONO, Tomohiro SEKI
  • Publication number: 20210024929
    Abstract: Developed and provided is: a nucleic acid agent that is efficiently delivered to the central nervous system, to which drug delivery is inhibited by the blood brain barrier mechanism, and that provides an antisense effect to a target transcription product at the delivery site; and a composition containing such a nucleic acid agent. Provided is a double-stranded nucleic acid complex consisting of a first nucleic acid strand and a second nucleic acid strand that are annealed to each other; wherein the first nucleic acid strand hybridizes with part of a target transcription product and has an antisense effect on the target transcription product; and wherein the second nucleic acid strand includes a base sequence complementary to the first nucleic acid strand and is conjugated to a phosphatidylethanolamine or an analog thereof.
    Type: Application
    Filed: March 13, 2019
    Publication date: January 28, 2021
    Applicants: National University Corporation Tokyo Medical and Dental University, Takeda Pharmaceutical Company Limited
    Inventors: Takanori Yokota, Tetsuya Nagata, Hideki Furukawa, Yasuo Nakagawa, Takatoshi Yogo, Ryosuke Tokunoh, Shigekazu Sasaki, Kosuke Hidaka, Tomohiro Seki, Kenichi Miyata, Akio Uchida
  • Patent number: 10804833
    Abstract: Provided is a control device for an electric generator/motor, which includes an armature winding and a field winding, the control device including: a bridge circuit configured to energize the armature winding; a field circuit configured to energize the field winding; and an energization control unit configured to control the energization of the bridge circuit and the field circuit. The energization control unit is configured to perform, when performing switching between a generation mode and a drive mode in response to an external command to control the electric generator/motor, control on a current supply amount for the field winding, and vector control on a current supply amount for the armature winding so as to compensate for a variation in field current.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: October 13, 2020
    Assignee: Mitsubishi Electric Corporation
    Inventors: Tomohiro Seki, Yuya Hisano, Ryo Nakamura
  • Patent number: 10787462
    Abstract: The present invention provides a heterocyclic compound having an RIP1 kinase inhibitory action, which is useful for the prophylaxis or treatment of Gaucher's disease, Niemann-Pick disease, inflammatory bowel disease, multiple sclerosis, chronic kidney disease, acute kidney injury, acute hepatic failure, autoimmune hepatitis, hepatitis B, hepatitis C, alcohol steatohepatitis, non-alcohol steatohepatitis and the like. The present invention relates to a compound represented by the following formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: September 29, 2020
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Takatoshi Yogo, Masato Yoshikawa, Morihisa Saitoh, Taisuke Katoh, Tomohiro Seki, Yoshihisa Nakada
  • Publication number: 20200266748
    Abstract: To provide a controller of rotary electric machine which can control voltage of each set of the winding appropriately within a range less than or equal to the DC power voltage, to the rotary electric machine which has plural sets of windings. A controller of rotary electric machine calculates, for each set, a required DC voltage which is a minimum DC power voltage required for applying a voltage according to the voltage command value to the winding, based on the voltage command value; calculates one common required DC voltage which is common to all sets, based on all sets of the required DC voltages; changes the common voltage control value so that the common required DC voltage-approaches the DC power voltage; and changes each set of the current command value based on the common voltage control value.
    Type: Application
    Filed: January 10, 2018
    Publication date: August 20, 2020
    Applicant: Mitsubishi Electric Corporation
    Inventors: Tomohiro SEKI, Ryo NAKAMURA, Yuya HISANO, Masahiro IEZAWA
  • Publication number: 20190253012
    Abstract: Provided is a control device for an electric generator/motor, which includes an armature winding and a field winding, the control device including: a bridge circuit configured to energize the armature winding; a field circuit configured to energize the field winding; and an energization control unit configured to control the energization of the bridge circuit and the field circuit. The energization control unit is configured to perform, when performing switching between a generation mode and a drive mode in response to an external command to control the electric generator/motor, control on a current supply amount for the field winding, and vector control on a current supply amount for the armature winding so as to compensate for a variation in field current.
    Type: Application
    Filed: November 2, 2016
    Publication date: August 15, 2019
    Applicant: Mitsubishi Electric Corporation
    Inventors: Tomohiro SEKI, Yuya HISANO, Ryo NAKAMURA
  • Publication number: 20190192549
    Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.
    Type: Application
    Filed: November 9, 2018
    Publication date: June 27, 2019
    Inventors: MASATO YOSHIKAWA, Morihisa Saitoh, Taisuke Kato, Yayoi Yoshitomi, Tomohiro Seki, Yasuo Nakagawa, Yusuke Tominari, Masaki Seto, Yusuke Sasaki, Masanori Okaniwa, Tsuneo Oda, Akito Shibuya, Kosuke Hidaka, Zenyu Shiokawa, Shumpei Murata, Atsutoshi Okabe, Yoshihisa Nakada, Michiyo Mochizuki, Brian Scott Freeze, Taisuke Tawaraishi, Yasufumi Wada, Paul D. Greenspan
  • Patent number: 10247549
    Abstract: A shaft accuracy measuring device includes: a measurement unit including a light projecting unit that projects a measuring light and a light receiving unit that receives the measurement light projected by the light projecting unit; a motor installation unit that installs the motor such that the output shaft of the motor is disposed between the light projecting unit and the light receiving unit; and a calculation unit that calculates at least one of axial run-out, center run-out, and face run-out of the motor based on a measurement result of the measurement unit.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: April 2, 2019
    Assignee: FANUC CORPORATION
    Inventors: SeungJun Lee, Hidetoshi Uematsu, Tomohiro Seki
  • Publication number: 20180319819
    Abstract: The present invention provides a heterocyclic compound having an RIP1 kinase inhibitory action, which is useful for the prophylaxis or treatment of Gaucher's disease, Niemann-Pick disease, inflammatory bowel disease, multiple sclerosis, chronic kidney disease, acute kidney injury, acute hepatic failure, autoimmune hepatitis, hepatitis B, hepatitis C, alcohol steatohepatitis, non-alcohol steatohepatitis and the like. The present invention relates to a compound represented by the following formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
    Type: Application
    Filed: October 21, 2016
    Publication date: November 8, 2018
    Inventors: Takatoshi YOGO, Masato YOSHIKAWA, Morihisa SAITOH, Taisuke KATOH, Tomohiro SEKI, Yoshihisa NAKADA