Patents by Inventor Tomohiro Seki
Tomohiro Seki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240140286Abstract: An air supply apparatus supplies air to an airbag of a seat includes a support panel and a functional component. A first direction is a thickness of the base, a second direction is orthogonal to the first direction, and a direction orthogonal to both the first direction and the second direction is a third direction. A first restriction wall and a second restriction wall extend from the base in the first direction, spaced at an interval in the second direction, and sandwich the functional component in the second direction. A coupling wall extends from the base in the first direction and couples the first restriction wall to the second restriction wall in the second direction. Two guide walls are spaced in the third direction and sandwich the functional component in the third direction. Pressing portions sandwich the functional component together with the coupling wall in the first direction.Type: ApplicationFiled: October 10, 2023Publication date: May 2, 2024Applicant: AISIN CORPORATIONInventors: Satoshi MASUDA, Tomokazu SEKI, Tomohiro HORI, Reiji SUZUKI
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Publication number: 20240066047Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.Type: ApplicationFiled: May 1, 2023Publication date: February 29, 2024Inventors: MASATO YOSHIKAWA, MORIHISA SAITOH, TAISUKE KATO, YAYOI NAKAYAMA, TOMOHIRO SEKI, YASUO NAKAGAWA, YUSUKE TOMINARI, MASAKI SETO, YUSUKE SASAKI, MASANORI OKANIWA, TSUNEO ODA, AKITO SHIBUYA, KOSUKE HIDAKA, ZENYU SHIOKAWA, SHUMPEI MURATA, ATSUTOSHI OKABE, YOSHIHISA NAKADA, MICHIYO MOCHIZUKI, BRIAN SCOTT FREEZE, TAISUKE TAWARAISHI, YASUFUMI WADA, PAUL D. GREENSPAN
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Publication number: 20230295628Abstract: Developed and provided is: a nucleic acid agent that is efficiently delivered to the central nervous system, to which drug delivery is inhibited by the blood brain barrier mechanism, and that provides an antisense effect to a target transcription product at the delivery site; and a composition containing such a nucleic acid agent. Provided is a double-stranded nucleic acid complex consisting of a first nucleic acid strand and a second nucleic acid strand that are annealed to each other; wherein the first nucleic acid strand hybridizes with part of a target transcription product and has an antisense effect on the target transcription product; and wherein the second nucleic acid strand includes a base sequence complementary to the first nucleic acid strand and is conjugated to a phosphatidylethanolamine or an analog thereof.Type: ApplicationFiled: February 2, 2023Publication date: September 21, 2023Applicants: National University Corporation Tokyo Medical and Dental University, Takeda Pharmaceutical Company LimitedInventors: Takanori Yokota, Tetsuya Nagata, Hideki Furukawa, Yasuo Nakagawa, Takatoshi Yogo, Ryosuke Tokunoh, Shigekazu Sasaki, Kosuke Hidaka, Tomohiro Seki, Kenichi Miyata, Akio Uchida
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Patent number: 11666594Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.Type: GrantFiled: October 7, 2020Date of Patent: June 6, 2023Assignee: Takeda Pharmaceutical Company LimitedInventors: Masato Yoshikawa, Morihisa Saitoh, Taisuke Kato, Yayoi Nakayama, Tomohiro Seki, Yasuo Nakagawa, Yusuke Tominari, Masaki Seto, Yusuke Sasaki, Masanori Okaniwa, Tsuneo Oda, Akito Shibuya, Kosuke Hidaka, Zenyu Shiokawa, Shumpei Murata, Atsutoshi Okabe, Yoshihisa Nakada, Michiyo Mochizuki, Brian Scott Freeze, Taisuke Tawaraishi, Yasufumi Wada, Paul D. Greenspan
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Patent number: 11597928Abstract: Developed and provided is: a nucleic acid agent that is efficiently delivered to the central nervous system, to which drug delivery is inhibited by the blood brain barrier mechanism, and that provides an antisense effect to a target transcription product at the delivery site; and a composition containing such a nucleic acid agent. Provided is a double-stranded nucleic acid complex consisting of a first nucleic acid strand and a second nucleic acid strand that are annealed to each other; wherein the first nucleic acid strand hybridizes with part of a target transcription product and has an antisense effect on the target transcription product; and wherein the second nucleic acid strand includes a base sequence complementary to the first nucleic acid strand and is conjugated to a phosphatidylethanolamine or an analog thereof.Type: GrantFiled: March 13, 2019Date of Patent: March 7, 2023Assignees: National University Corporation Tokyo Medical and Dental University, Takeda Pharmaceutical Company LimitedInventors: Takanori Yokota, Tetsuya Nagata, Hideki Furukawa, Yasuo Nakagawa, Takatoshi Yogo, Ryosuke Tokunoh, Shigekazu Sasaki, Kosuke Hidaka, Tomohiro Seki, Kenichi Miyata, Akio Uchida
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Publication number: 20220370491Abstract: The object of the present invention is to provide a nucleic acid agent that is efficiently delivered to the nervous system, for example, the central nervous system to which drug delivery can be prevented by BBB, and produces an antisense effect on the target transcriptional product at the delivery site, and a composition comprising the same. In an embodiment, the present invention provides a double-stranded nucleic acid complex formed by annealing a first nucleic acid strand that hybridizes to a part of a target transcriptional product and has an antisense effect on the target transcriptional product, and a second nucleic acid strand that comprises a base sequence complementary to the first nucleic acid strand and is bound to a C22-35 alkyl group optionally substituted with a hydroxy group or an analog thereof.Type: ApplicationFiled: September 16, 2020Publication date: November 24, 2022Applicants: National University Corporation Tokyo Medical and Dental University, Takeda Pharmaceutical Company LimitedInventors: Takanori Yokota, Testuya Nagata, Hideki Furukawa, Takatoshi Yogo, Yasuo Nakagawa, Shigekazu Sasaki, Ryosuke Tokunoh, Tomohiro Seki, Kosuke Hidaka, Fumiaki Kikuchi, Osamu Kubo, Takahito Kasahara, Takuto Kojima, Junsi Wang, Norihito Tokunaga
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Patent number: 11081998Abstract: To provide a controller of rotary electric machine which can control voltage of each set of the winding appropriately within a range less than or equal to the DC power voltage, to the rotary electric machine which has plural sets of windings. A controller of rotary electric machine calculates, for each set, a required DC voltage which is a minimum DC power voltage required for applying a voltage according to the voltage command value to the winding, based on the voltage command value; calculates one common required DC voltage which is common to all sets, based on all sets of the required DC voltages; changes the common voltage control value so that the common required DC voltage-approaches the DC power voltage; and changes each set of the current command value based on the common voltage control value.Type: GrantFiled: January 10, 2018Date of Patent: August 3, 2021Assignee: Mitsubishi Electric CorporationInventors: Tomohiro Seki, Ryo Nakamura, Yuya Hisano, Masahiro Iezawa
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Publication number: 20210163934Abstract: The object of the present invention is to provide a nucleic acid agent that can be efficiently delivered to the nervous system, particularly the central nervous system to which the BBB mechanism prevents drug delivery, and can produce an antisense effect on a target transcriptional product at the delivered site, and a composition comprising the same. Provided is a double-stranded nucleic acid complex formed by annealing a first nucleic acid strand capable of hybridizing to part of a target transcriptional product, and has an antisense effect on the target transcriptional product, to a second nucleic acid strand comprising a base sequence complementary to the first nucleic acid strand, and is bound to tocopherol or an analog thereof, cholesterol or an analog thereof, or a substituted or unsubstituted C1-30 alkyl group, a substituted or unsubstituted C2-30 alkenyl group, or a substituted or unsubstituted C1-30 alkoxy group.Type: ApplicationFiled: March 22, 2019Publication date: June 3, 2021Applicant: NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITYInventors: Takanori YOKOTA, Tetsuya NAGATA, Hideki FURUKAWA, Yasuo NAKAGAWA, Takatoshi YOGO, Ryosuke TOKUNOH, Shigekazu SASAKI, Kosuke HIDAKA, Tomohiro SEKI, Kenichi MIYATA, Yusuke ADACHI, Naoto ARIMURA
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Publication number: 20210137962Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.Type: ApplicationFiled: November 9, 2018Publication date: May 13, 2021Inventors: Masato Yoshikawa, Morihisa Saitoh, Taisuke Kato, Yayoi Yoshitomi, Tomohiro Seki, Yasuo Nakagawa, Yusuke Tominari, Masaki Seto, Akito Shibuya, Kosuke Hidaka, Zenyu Shiokawa, Yoshihisa Nakada, Michiyo Mochizuki
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Patent number: 10980825Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.Type: GrantFiled: November 9, 2018Date of Patent: April 20, 2021Assignee: Takeda Pharmaceutical Company LimitedInventors: Masato Yoshikawa, Morihisa Saitoh, Taisuke Kato, Yayoi Nakayama, Tomohiro Seki, Yasuo Nakagawa, Yusuke Tominari, Masaki Seto, Akito Shibuya, Kosuke Hidaka, Zenyu Shiokawa, Yoshihisa Nakada, Michiyo Mochizuki
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Publication number: 20210106607Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.Type: ApplicationFiled: October 7, 2020Publication date: April 15, 2021Inventors: MASATO YOSHIKAWA, Morihisa Saitoh, Taisuke Kato, Yayoi Nakayama, Tomohiro Seki, Yasuo Nakagawa, Yusuke Tominari, Masaki Seto, Yusuke Sasaki, Masanori Okaniwa, Tsuneo Oda, Akito Shibuya, Kosuke Hidaka, Zenyu Shiokawa, Shumpei Murata, Atsutoshi Okabe, Yoshihisa Nakada, Michiyo Mochizuki, Brian Scott Freeze, Taisuke Tawaraishi, Yasufumi Wada, Paul D. Greenspan
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Publication number: 20210061833Abstract: The lanthanoid compound according to the present invention is a compound represented by the following general formula Ln(R1xCp)2(A)y or the following general formula Sm(R2xCp)2(A)y. In Ln(R1xCp)2(A)y, Ln is Nd, Eu, Dy, Tm, or Yb, R1 is independently Me, Et, nPr, iPr, nBt, sBu, iBu, or tAm, Cp is cyclopentadienyl, A is a linear or cyclic hydrocarbon containing oxygen, sulfur, phosphorus, or nitrogen, x is an integer of 2 to 3, and y is 0 to 2. In Sm(R2xCp)2(A)y, R2 is independently nPr, iPr, nBt, sBu, iBu, or tAm.Type: ApplicationFiled: January 22, 2019Publication date: March 4, 2021Inventors: Christian DUSSARRAT, Takashi ONO, Tomohiro SEKI
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Publication number: 20210024929Abstract: Developed and provided is: a nucleic acid agent that is efficiently delivered to the central nervous system, to which drug delivery is inhibited by the blood brain barrier mechanism, and that provides an antisense effect to a target transcription product at the delivery site; and a composition containing such a nucleic acid agent. Provided is a double-stranded nucleic acid complex consisting of a first nucleic acid strand and a second nucleic acid strand that are annealed to each other; wherein the first nucleic acid strand hybridizes with part of a target transcription product and has an antisense effect on the target transcription product; and wherein the second nucleic acid strand includes a base sequence complementary to the first nucleic acid strand and is conjugated to a phosphatidylethanolamine or an analog thereof.Type: ApplicationFiled: March 13, 2019Publication date: January 28, 2021Applicants: National University Corporation Tokyo Medical and Dental University, Takeda Pharmaceutical Company LimitedInventors: Takanori Yokota, Tetsuya Nagata, Hideki Furukawa, Yasuo Nakagawa, Takatoshi Yogo, Ryosuke Tokunoh, Shigekazu Sasaki, Kosuke Hidaka, Tomohiro Seki, Kenichi Miyata, Akio Uchida
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Patent number: 10804833Abstract: Provided is a control device for an electric generator/motor, which includes an armature winding and a field winding, the control device including: a bridge circuit configured to energize the armature winding; a field circuit configured to energize the field winding; and an energization control unit configured to control the energization of the bridge circuit and the field circuit. The energization control unit is configured to perform, when performing switching between a generation mode and a drive mode in response to an external command to control the electric generator/motor, control on a current supply amount for the field winding, and vector control on a current supply amount for the armature winding so as to compensate for a variation in field current.Type: GrantFiled: November 2, 2016Date of Patent: October 13, 2020Assignee: Mitsubishi Electric CorporationInventors: Tomohiro Seki, Yuya Hisano, Ryo Nakamura
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Patent number: 10787462Abstract: The present invention provides a heterocyclic compound having an RIP1 kinase inhibitory action, which is useful for the prophylaxis or treatment of Gaucher's disease, Niemann-Pick disease, inflammatory bowel disease, multiple sclerosis, chronic kidney disease, acute kidney injury, acute hepatic failure, autoimmune hepatitis, hepatitis B, hepatitis C, alcohol steatohepatitis, non-alcohol steatohepatitis and the like. The present invention relates to a compound represented by the following formula (I): wherein each symbol is as defined in the specification, or a salt thereof.Type: GrantFiled: October 21, 2016Date of Patent: September 29, 2020Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITEDInventors: Takatoshi Yogo, Masato Yoshikawa, Morihisa Saitoh, Taisuke Katoh, Tomohiro Seki, Yoshihisa Nakada
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Publication number: 20200266748Abstract: To provide a controller of rotary electric machine which can control voltage of each set of the winding appropriately within a range less than or equal to the DC power voltage, to the rotary electric machine which has plural sets of windings. A controller of rotary electric machine calculates, for each set, a required DC voltage which is a minimum DC power voltage required for applying a voltage according to the voltage command value to the winding, based on the voltage command value; calculates one common required DC voltage which is common to all sets, based on all sets of the required DC voltages; changes the common voltage control value so that the common required DC voltage-approaches the DC power voltage; and changes each set of the current command value based on the common voltage control value.Type: ApplicationFiled: January 10, 2018Publication date: August 20, 2020Applicant: Mitsubishi Electric CorporationInventors: Tomohiro SEKI, Ryo NAKAMURA, Yuya HISANO, Masahiro IEZAWA
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Publication number: 20190253012Abstract: Provided is a control device for an electric generator/motor, which includes an armature winding and a field winding, the control device including: a bridge circuit configured to energize the armature winding; a field circuit configured to energize the field winding; and an energization control unit configured to control the energization of the bridge circuit and the field circuit. The energization control unit is configured to perform, when performing switching between a generation mode and a drive mode in response to an external command to control the electric generator/motor, control on a current supply amount for the field winding, and vector control on a current supply amount for the armature winding so as to compensate for a variation in field current.Type: ApplicationFiled: November 2, 2016Publication date: August 15, 2019Applicant: Mitsubishi Electric CorporationInventors: Tomohiro SEKI, Yuya HISANO, Ryo NAKAMURA
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Publication number: 20190192549Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.Type: ApplicationFiled: November 9, 2018Publication date: June 27, 2019Inventors: MASATO YOSHIKAWA, Morihisa Saitoh, Taisuke Kato, Yayoi Yoshitomi, Tomohiro Seki, Yasuo Nakagawa, Yusuke Tominari, Masaki Seto, Yusuke Sasaki, Masanori Okaniwa, Tsuneo Oda, Akito Shibuya, Kosuke Hidaka, Zenyu Shiokawa, Shumpei Murata, Atsutoshi Okabe, Yoshihisa Nakada, Michiyo Mochizuki, Brian Scott Freeze, Taisuke Tawaraishi, Yasufumi Wada, Paul D. Greenspan
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Patent number: 10247549Abstract: A shaft accuracy measuring device includes: a measurement unit including a light projecting unit that projects a measuring light and a light receiving unit that receives the measurement light projected by the light projecting unit; a motor installation unit that installs the motor such that the output shaft of the motor is disposed between the light projecting unit and the light receiving unit; and a calculation unit that calculates at least one of axial run-out, center run-out, and face run-out of the motor based on a measurement result of the measurement unit.Type: GrantFiled: March 25, 2016Date of Patent: April 2, 2019Assignee: FANUC CORPORATIONInventors: SeungJun Lee, Hidetoshi Uematsu, Tomohiro Seki
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Publication number: 20180319819Abstract: The present invention provides a heterocyclic compound having an RIP1 kinase inhibitory action, which is useful for the prophylaxis or treatment of Gaucher's disease, Niemann-Pick disease, inflammatory bowel disease, multiple sclerosis, chronic kidney disease, acute kidney injury, acute hepatic failure, autoimmune hepatitis, hepatitis B, hepatitis C, alcohol steatohepatitis, non-alcohol steatohepatitis and the like. The present invention relates to a compound represented by the following formula (I): wherein each symbol is as defined in the specification, or a salt thereof.Type: ApplicationFiled: October 21, 2016Publication date: November 8, 2018Inventors: Takatoshi YOGO, Masato YOSHIKAWA, Morihisa SAITOH, Taisuke KATOH, Tomohiro SEKI, Yoshihisa NAKADA