Patents by Inventor Tomoko Hirama

Tomoko Hirama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Screening of protein candidates
    Patent number: 10627400
    Abstract: Successful application of an engineered protein as therapeutics or in other industries would require the protein to have good expression level, good biophysical properties and often desired affinity to its target. The present invention provides s method of screening large numbers of protein candidates (PCs) in all three aspects simultaneously. PCs are fused to a protein anchor, which is captured by the target/antigen. The captured PCs are evaluated for their expression levels, biophysical properties and affinities using conventional methods.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: April 21, 2020
    Assignee: National Research Council of Canada
    Inventors: Jianbing Zhang, Tomoko Hirama
  • SCREENING OF PROTEIN CANDIDATES
    Publication number: 20170122941
    Abstract: Successful application of an engineered protein as therapeutics or in other industries would require the protein to have good expression level, good biophysical properties and often desired affinity to its target. The present invention provides s method of screening large numbers of protein candidates (PCs) in all three aspects simultaneously. PCs are fused to a protein anchor, which is captured by the target/antigen. The captured PCs are evaluated for their expression levels, biophysical properties and affinities using conventional methods.
    Type: Application
    Filed: October 5, 2016
    Publication date: May 4, 2017
    Applicant: NATIONAL RESEARCH COUNCIL OF CANADA
    Inventors: Jianbing ZHANG, Tomoko HIRAMA
  • Screening of protein candidates
    Patent number: 9476887
    Abstract: Successful application of an engineered protein as therapeutics or in other industries would require the protein to have good expression level, good biophysical properties and often desired affinity to its target. The present invention provides a method of screening large numbers of protein candidates (PCs) in all three aspects simultaneously. PCs are fused to a protein anchor, which is captured by the target/antigen. The captured PCs are evaluated for their expression levels, biophysical properties and affinities using conventional methods.
    Type: Grant
    Filed: August 18, 2010
    Date of Patent: October 25, 2016
    Assignee: National Research Council of Canada
    Inventors: Jianbing Zhang, Tomoko Hirama
  • SCREENING OF PROTEIN CANDIDATES
    Publication number: 20120178110
    Abstract: Successful application of an engineered protein as therapeutics or in other industries would require the protein to have good expression level, good biophysical properties and often desired affinity to its target. The present invention provides a method of screening large numbers of protein candidates (PCs) in all three aspects simultaneously. PCs are fused to a protein anchor, which is captured by the target/antigen. The captured PCs are evaluated for their expression levels, biophysical properties and affinities using conventional methods.
    Type: Application
    Filed: August 18, 2010
    Publication date: July 12, 2012
    Applicant: National Research Council Canada
    Inventors: Jianbing Zhang, Tomoko Hirama