Patents by Inventor Tomoko Kosaka

Tomoko Kosaka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell culture of fetal liver in layered state in a partitioned micro-space
    Patent number: 9428721
    Abstract: Provided is a cell culture method whereby an in vivo function can be sustained over a long period of time and culture can be conducted using the minimum number of cells required. The cell culture method includes culturing undifferentiated cells in a layered state in a partitioned micro-space and obtains differentiated cells. When screening a pharmaceutical agent, undifferentiated cells capable of differentiating into liver cells, intestinal epithelial cells, nerve cells, myocardial cells and vascular endothelial cells are preferred. Particularly, in the prediction of pharmacokinetics or the like for humans, human cells are preferred.
    Type: Grant
    Filed: February 5, 2009
    Date of Patent: August 30, 2016
    Assignees: Public University Corporation Yokohama City University, KURARAY Co., Ltd.
    Inventors: Hideki Taniguchi, Yun-Wen Zheng, Go Tazaki, Tomoko Kosaka, Hitoshi Tsuruta, Motohiro Fukuda
  • Cell culture container and cell culture method
    Patent number: 8415157
    Abstract: A cell culture chamber and a cell culture method that are capable of effectively constructing an intercellular network in a culture space are provided. A cell culture chamber (10)according to the present invention is a cell culture chamber (10)including a plurality of microchambers (11) formed on a surface thereof, characterized in that convex portions (side walls 12) that partition the microchambers (11) adjacent to each other are formed to prevent cells from being adhered to upper surfaces of the convex portions. Consequently, cells can be cultured exclusively within the microchambers (11), and an intercellular network can be constructed effectively.
    Type: Grant
    Filed: September 9, 2011
    Date of Patent: April 9, 2013
    Assignee: KURARAY Co., Ltd.
    Inventors: Go Tazaki, Tomoko Kosaka, Motohiro Fukuda
  • CELL CULTURE CONTAINER AND CELL CULTURE METHOD
    Publication number: 20110318829
    Abstract: To provide a cell culture chamber and a cell culture method that are capable of effectively constructing an intercellular network in a culture space. A cell culture chamber (10) according to the present invention is a cell culture chamber (10) including a plurality of microchambers (11) formed on a surface thereof, characterized in that convex portions (side walls 12) that partition the microchambers (11) adjacent to each other are formed to prevent cells from being adhered to upper surfaces of the convex portions. Consequently, cells can be cultured exclusively within the microchambers (11), and an intercellular network can be constructed effectively.
    Type: Application
    Filed: September 9, 2011
    Publication date: December 29, 2011
    Applicant: KURARAY CO., LTD.
    Inventors: Go TAZAKI, Tomoko Kosaka, Motohiro Fukuda
  • CELL CULTURE METHOD AND SCREENING METHOD
    Publication number: 20110045500
    Abstract: Provided is a cell culture method whereby an in vivo function can be sustained over a long period of time and culture can be conducted using the minimum number of cells required. The cell culture method includes culturing undifferentiated cells in a layered state in a partitioned micro-space and obtains differentiated cells. When screening a pharmaceutical agent, undifferentiated cells capable of differentiating into liver cells, intestinal epithelial cells, nerve cells, myocardial cells and vascular endothelial cells are preferred. Particularly, in the prediction of pharmacokinetics or the like for humans, human cells are preferred.
    Type: Application
    Filed: February 5, 2009
    Publication date: February 24, 2011
    Applicants: PUBLIC UNIVERSITY CORP. YOKOHAMA CITY UNIVERSITY, KURARAY CO., LTD.
    Inventors: Hideki Taniguchi, Yun-Wen Zheng, Go Tazaki, Tomoko Kosaka, Hitoshi Tsuruta, Motohiro Fukuda
  • CELL CULTURE CONTAINER AND CELL CULTURE METHOD
    Publication number: 20100190253
    Abstract: To provide a cell culture chamber and a cell culture method that are capable of effectively constructing an intercellular network in a culture space. A cell culture chamber (10) according to the present invention is a cell culture chamber (10) including a plurality of microchambers (11) formed on a surface thereof, characterized in that convex portions (side walls 12) that partition the microchambers (11) adjacent to each other are formed to prevent cells from being adhered to upper surfaces of the convex portions. Consequently, cells can be cultured exclusively within the microchambers (11), and an intercellular network can be constructed effectively.
    Type: Application
    Filed: June 16, 2008
    Publication date: July 29, 2010
    Applicant: KURARAY CO., LTD.
    Inventors: Go Tazaki, Tomoko Kosaka, Motohiro Fukuda