Abstract: The present invention provides an antibody that binds to an NTCP, capable of inhibiting infection of human hepatocytes with hepatitis B virus (HBV) particles. The present invention also provides an antibody that binds to an NTCP, capable of inhibiting infection of human hepatocytes with hepatitis B virus (HBV) particles, the antibody having a reduced effect on bile acid transport by NTCP.

Abstract: A front derailleur is provided for mounting to a bicycle having a crank axis. The front derailleur is provided with a base member, a chain guide and a link mechanism. The base member is mounted on the bicycle for positioning in a predetermined adjustment direction. The chain guide guides the chain. The link mechanism movably couples the chain guide to the base member. The link mechanism includes a first link member pivotally arranged in relation to the base member about a first link axis and pivotally arranged in relation to the chain guide about a second link axis. The first link axis and the second link axis are arranged non-parallel and non-orthogonal to the predetermined adjustment direction when viewed from the axial direction of the crank axis in a state where the base member is mounted to the bicycle.

Abstract: A derailleur comprises a base member, a movable member, a link member, and a biasing mechanism. The movable member is configured to be movable with respect to the base member between a retracted position and an extended position. The link member is configured to movably couple the movable member to the base member. The biasing mechanism is configured to bias the link member such that the movable member is disposed at one of the retracted position and the extended position. The biasing mechanism comprises a biasing member and an intermediate member. The biasing member has a first end portion. The intermediate member is separately provided from the movable member and the link member so as to transmit biasing force of the biasing member from the first end portion to one of the movable member and the link member through the intermediate member.

Abstract: A derailleur comprises a base member, a movable member, a link member, and a biasing mechanism. The movable member is configured to be movable with respect to the base member between a retracted position and an extended position. The link member is configured to movably couple the movable member to the base member. The biasing mechanism is configured to bias the link member such that the movable member is disposed at one of the retracted position and the extended position. The biasing mechanism comprises a biasing member and an intermediate member. The biasing member has a first end portion. The intermediate member is separately provided from the movable member and the link member so as to transmit biasing force of the biasing member from the first end portion to one of the movable member and the link member through the intermediate member.

Abstract: A front derailleur is provided for mounting to a bicycle having a crank axis. The front derailleur is provided with a base member, a chain guide and a link mechanism. The base member is mounted on the bicycle for positioning in a predetermined adjustment direction. The chain guide guides the chain. The link mechanism movably couples the chain guide to the base member. The link mechanism includes a first link member pivotally arranged in relation to the base member about a first link axis and pivotally arranged in relation to the chain guide about a second link axis. The first link axis and the second link axis are arranged non-parallel and non-orthogonal to the predetermined adjustment direction when viewed from the axial direction of the crank axis in a state where the base member is mounted to the bicycle.