Abstract: A cell culture method includes performing adherent culture of cells on a coat layer layered on a surface of a cell culture container by placing a culture medium and the cells in the cell culture container. The coat layer includes a layer (i) that includes a layer (i-1) including gelatin or casein and a layer (i-2) that includes a polycationic material and a layer (ii) that is layered on the layer (i) and includes a cell adhesion factor. The layer (ii) is disposed at a position at which the layer (ii) comes into contact with the cells, or the coat layer includes the layer (i) and the layer (i) is disposed at a position at which the layer (i) comes into contact with the cells, and the culture medium includes the cell adhesion factor.

Abstract: At least one of a discharging tendency of waste based on a discharge history of discharge of the waste by a user of a service and a discharge prediction about the waste based on the purchase history of a product by the user is calculated. A need prediction about the service is calculated by using a prediction model which uses, as a parameter, at least one of the discharging tendency of the waste and the discharge prediction about the waste. A level of the service is estimated by a simulation which uses, as parameters, the need prediction and a resource employed for the service. A notification is transmitted to the user suggesting a modification of behavior of at least one of discharge of the waste and purchase of a product by the user based on a comparison result between an estimated level and a stipulated level of the service.

Abstract: The method of the present disclosure comprises the following first to fourth steps. The first step is a step of calculating, by simulation, a model time requited for each action of object handling work for an object handled in a distribution center. The second step is a step of determining a start time and an end time of each action based on an analysis of camera image data obtained in the distribution center. The third step is a step of calculating an actual time required for each action from a time difference between the start time and the end time of each action. The fourth step is a step of calculating a difference between the actual time required and the model time required for each action.

Abstract: The method of the present disclosure comprises the following first to fourth steps. The first step is a step of determining a start timing and an end timing of each action of object handling work for a dummy object imitating an object handled in a distribution center, based on an analysis of position data of the dummy object when the dummy object is flowed to a distribution line of the distribution center. The second step is a step of calculating a model time required for each action based on the start timing and the end timing of each action. The third step is a step of calculating an actual time required for each action when the object is actually flowed to the distribution line. The fourth step is a step of calculating a difference between the actual time required and the model time required for each action.

Abstract: The service optimization system performs simulation using a human model modeling service utilization behavior of a customer to predict a demand for a service from real data including at least one of behavior, behavior history, and behavior schedule of the customer related to the service. Also, the service optimization system performs simulation using a service model modeling a relationship between a service parameter determining content of the service, a demand for the service, and a level of the service to determine a setting value of the service parameter for maintaining the level of the service based on the predicted demand. Then, the service optimization system acquires the real data after the service is provided using the determined setting value of the service parameter to feed back the acquired real data to an input of the simulation using the human model.

Abstract: A service management system for managing a service includes: one or more memory devices configured to store user personality information indicating personality for each user of the service; and one or more processors. The one or more processors are configured to execute: a service simulation process that simulates a state of the service to estimate a level of the service, based on demand forecast information for the service; and a change promotion process that notifies a user of change promotion information that promotes a change in a requirement or an action for the service, when the level of the service is lower than a predetermined level. The change promotion process includes notifying the change promotion information according to the personality of the user based on the user personality information.

Abstract: A simulation is performed using a digital space reproduced based on a real space in which a service is provided. Based on a simulation result satisfying a predetermined convergence condition, a threshold for detecting occurrence of an abnormality in one or more works performed in association with provision of the service in the real space may be set for each work unit corresponding to the one or more works. When the threshold is set, the time difference between the preset standard working time and the simulated work time included in the simulation result satisfying the convergent condition is calculated. A larger threshold value is assigned to a work unit having a larger time difference than a work unit having a smaller time difference.

Abstract: The method of the present disclosure is a management method for a logistics area with a work line constituted of a plurality of work subjects. The method comprises: simulating a work space in which the plurality of work subjects work; monitoring an actual movement of each of the plurality of work subjects in the work space; detecting a deviation between a simulated movement and a monitored actual movement for each of the plurality of work subjects; and acquiring, in response to detection of the deviation, information on a factor affecting a movement of a work subject in which the deviation occurs.

Abstract: The method of the present disclosure is a management method for a logistics area with a work line constituted of a plurality of work subjects. The method comprises: simulating, using a digital twin, a work space in which the plurality of work subjects work; monitoring an actual movement of each of the plurality of work subjects in the work space; and displaying each of the plurality of work subjects on a screen simulating the work space as a heat map of which a color is changed in accordance with a degree of deviation between a movement simulated using the digital twin and a monitored actual movement.

Abstract: A treatment instrument includes a first treatment portion including a first member with a first contact surface and a second member with a second contact surface; a movement mechanism to switch between a closed position where the first and second contact surfaces are close to each other and an open position where the first and second contact surfaces are separated each other; and a second treatment portion juxtaposed to the first treatment portion. A distal end of the second treatment portion is located at a distal side in the longitudinal axis than a distal end of the first treatment portion on the closed position.

Abstract: A treatment instrument includes: a first treatment section which includes a first body including a first contact surface and a second body including a second contact surface; a movement mechanism which is configured to switch between a closed position in which the first contact surface and the second contact surface are close to each other, and an opened position in which the first contact surface and the second contact surface are distant from each other; and a second treatment section which is disposed on a distal side along the longitudinal axis with respect to the first treatment section when the first contact surface and the second contact surface are located in the closed position, and which is configured to apply energy to the living tissue to incise or separate the living tissue.

Abstract: A treatment tool includes a sheath, a first grasping member, a second grasping member and a swing member. The first grasping member protrudes from a distal portion of the sheath. The second grasping member is rotatably provided to the sheath so that a first angle, which is an angle formed with the first grasping member, changes. The swing member is provided to the second grasping member so as to swing and so that a second angle, which is an angle formed with the second grasping member, changes. When the second angle is at its maximum, there is a first angle at which the first grasping member and the swing member do not contact each other.

Abstract: A forceps-type treatment instrument includes an end effector including a pair of clamps. In one of the clamps, a swinger is extended along an extending axis and swings relative to a supporting section around a swing axis extended along a direction intersecting with the extending axis and intersecting with an open and close direction of the clamp. A regulating section regulates movement of the swinger in the direction along the swing axis in at least two portions separated from each other in a direction along the extending axis, and thereby prevents rotation of the swinger around a rotation axis along the open and close direction.

Abstract: A treatment instrument includes a first treatment portion including a first member with a first contact surface and a second member with a second contact surface; a movement mechanism to switch between a closed position where the first and second contact surfaces are close to each other and an open position where the first and second contact surfaces are separated each other; and a second treatment portion juxtaposed to the first treatment portion. A distal end of the second treatment portion is located at a distal side in the longitudinal axis than a distal end of the first treatment portion on the closed position.

Abstract: A treatment instrument includes: a first treatment section which includes a first body including a first contact surface and a second body including a second contact surface; a movement mechanism which is configured to switch between a closed position in which the first contact surface and the second contact surface are close to each other, and an opened position in which the first contact surface and the second contact surface are distant from each other; and a second treatment section which is disposed on a distal side along the longitudinal axis with respect to the first treatment section when the first contact surface and the second contact surface are located in the closed position, and which is configured to apply energy to the living tissue to incise or separate the living tissue.

Abstract: A grasping treatment device includes a probe including a first electrode portion in its distal portion, and a jaw configured to open or close relative to the first electrode portion and including a second electrode portion. The grasping treatment device includes a grasping force converting unit converting a grasping force so that a second grasping force between the distal portion of the probe and the jaw in a second treatment mode in which high-frequency current alone is transmitted to the first electrode portion and the second electrode portion is greater than a first grasping force between the distal portion of the probe and the jaw in a first treatment mode in which at least an ultrasonic vibration is transmitted to the distal portion of the probe.

Abstract: A grasping treatment device includes a probe including a first electrode portion in its distal portion, and a jaw configured to open or close relative to the first electrode portion and including a second electrode portion. The grasping treatment device includes a grasping force converting unit converting a grasping force so that a second grasping force between the distal portion of the probe and the jaw in a second treatment mode in which high-frequency current alone is transmitted to the first electrode portion and the second electrode portion is greater than a first grasping force between the distal portion of the probe and the jaw in a first treatment mode in which at least an ultrasonic vibration is transmitted to the distal portion of the probe.

Abstract: A method for visualizing the execution of a software program especially in an embedded system. A plurality of interconnected program modules are displayed on a display device wherein at least one of the modules has at least two mutually exclusive different modes of functionality. A unique color is assigned to each mode of functionality. During the execution of the software program, the mode of functionality for each program module during execution of that module is selected as a function of software parameters of the software program. The color of the software module on the display device is then changed to correspond to the color assigned to the selected mode of functionality for the program modules during the execution of the program.

Abstract: A method for visualizing the execution of a software program especially in an embedded system. A plurality of interconnected program modules are displayed on a display device wherein at least one of the modules has at least two mutually exclusive different modes of functionality. A unique color is assigned to each mode of functionality. During the execution of the software program, the mode of functionality for each program module during execution of that module is selected as a function of software parameters of the software program. The color of the software module on the display device is then changed to correspond to the color assigned to the selected mode of functionality for the program modules during the execution of the program.