Abstract: An objective of the present invention is to provide target tissue-specific antigen-binding molecules, antigen-binding molecules whose antigen-binding activity varies depending on the concentration of an unnatural compound, libraries comprising a plurality of the antigen-binding molecules which are different from one another, pharmaceutical compositions comprising the antigen-binding molecules, methods of screening for the antigen-binding molecules, and methods for producing the antigen-binding molecules. The present inventors created antigen-binding domains whose antigen-binding activity varies depending on the concentration of a small molecule compound or antigen-binding molecules containing an antigen-binding domain, and libraries comprising a plurality of the antigen-binding domains which are different from one another or antigen-binding domains, and demonstrated that the above-noted objective could be achieved by using the libraries.

Abstract: An objective of the present invention is to provide target tissue-specific antigen-binding molecules, antigen-binding molecules whose antigen-binding activity varies depending on the concentration of an unnatural compound, libraries comprising a plurality of the antigen-binding molecules which are different from one another, pharmaceutical compositions comprising the antigen-binding molecules, methods of screening for the antigen-binding molecules, and methods for producing the antigen-binding molecules. The present inventors created antigen-binding domains whose antigen-binding activity varies depending on the concentration of a small molecule compound or antigen-binding molecules containing an antigen-binding domain, and libraries comprising a plurality of the antigen-binding domains which are different from one another or antigen-binding domains, and demonstrated that the above-noted objective could be achieved by using the libraries.

Abstract: An air conditioner control system comprises air conditioners configured to condition an environment in a target space, an integrated controller configured to control the air conditioners based on control parameter data, sensor devices configured to measure the temperature of the target space and transmit measurement data, and wireless master devices configured to create control parameter data based on the measurement data. The wireless master devices each determine sleep times so that at least two sensor devices run out of battery charge around the same time according to the remaining charge amount of each of the sensor devices. The sensor devices each will be in the sleep mode in which power consumption is lower than in the normal mode according to the sleep time decided by the wireless master devices.

Abstract: An air conditioner control system comprises air conditioners configured to condition an environment in a target space, an integrated controller configured to control the air conditioners based on control parameter data, sensor devices configured to measure the temperature of the target space and transmit measurement data, and wireless master devices configured to create control parameter data based on the measurement data. The wireless master devices each determine sleep times so that at least two sensor devices run out of battery charge around the same time according to the remaining charge amount of each of the sensor devices. The sensor devices each will be in the sleep mode in which power consumption is lower than in the normal mode according to the sleep time decided by the wireless master devices.