Abstract: The use of a genetic method to down-regulate RBO/EFR3/EFR3A/EFR3B proteins, TTC7 protein or PI4KIII? enzyme protein which interacts with RBO/EFR3/EFR3A/EFR3B proteins and TTC7 protein, or the use of a drug to inhibit PI4KIII? protein kinase activity reduces the accumulation of A?42 within neurons and age-dependent synaptic transmission failure and other obstacles in a fruit fly AD model, and obtains an effect of improving the learning and memory abilities of AD model mice. Provided is a method for using an RBO/EFR3/EFR3A/EFR3B inhibitor, a TTC7 inhibitor and a PI4KIII? inhibitor to treat Alzheimer's disease. Also provided is a method for screening a drug treating Alzheimer's disease by whether A? secretion by nerve cells is promoted or not.

Abstract: The invention discloses a convenient human and animal power drive permanent magnet power generation and storage system, comprising a grip power drive power generation system; the grip power drive power generation system is a dumbbell-shaped grip power generation device, comprising a grip handle and power generation devices provided at both ends of the grip handle; the power generation device is composed of a permanent magnet generator, a tensioning wheel, a spring sheet, a winder ratchet device, and a battery; folding buckles are provided between the power generation devices at both ends and the grip handle so as to be folded inward. The invention solves the problem of continuous power guarantee of wearable intelligent device; in the invention, the grip-type slow gear is designed as a spring tensioning device similar to a mechanical watch; the stress generated during the grip tightens the spring.

Abstract: Provided are antibodies that specifically bind to T-cell immunoglobulin domain and mucin domain 3 (Tim-3). The anti-Tim-3 antibodies can be used to treat, prevent or diagnose immune, cancerous, infectious diseases or other pathological disorders that may be modulated by Tim-3-mediated functions.

Abstract: The present disclosure provides a compact bionic eye device based on a two-degree-of-freedom electromagnetically-driven rotating mechanism, which can be used as a vision sensor of bionic robots such as humanoid robots. The compact bionic eye device includes a rotor, stator cores, windings, an angular displacement camera, a spherical hinge pressing block, a stator connector, a camera, a spherical hinge, a camera connector, a rotor connector and an outer spherical shell. According to the compact bionic eye device of the present disclosure, the rotor is driven to achieve limited rotation with pitching and yawing degrees of freedom by regulating a current of the windings of four stators. By adopting a two-degree-of-freedom of electromagnetically-driven rotating mechanism which is compact in structure, the bionic eye device of the present disclosure can achieve a human eye size, and provides important foundation for practical application of bionic eyes in humanoid robots.

Abstract: Methods for forming polyolefin nanocomposite precursor compositions are provided. In embodiments, such a method comprises mixing a polyolefin, unmodified graphite, and a peroxide crosslinker via solid-state shear pulverization under conditions to form a polyolefin nanocomposite precursor composition comprising the polyolefin; exfoliated, unmodified graphite dispersed throughout the polyolefin; and unreacted peroxide crosslinker dispersed throughout the polyolefin, wherein the polyolefin is polyethylene, a copolymer of polyethylene, or combinations thereof. Methods of forming crosslinked polyolefin nanocomposites, the polyolefin nanocomposite precursor compositions, and crosslinked polyolefin nanocomposites are also provided.

Abstract: Methods for forming polyolefin nanocomposite precursor compositions are provided. In embodiments, such a method comprises mixing a polyolefin, unmodified graphite, and a peroxide crosslinker via solid-state shear pulverization under conditions to form a polyolefin nanocomposite precursor composition comprising the polyolefin; exfoliated, unmodified graphite dispersed throughout the polyolefin; and unreacted peroxide crosslinker dispersed throughout the polyolefin, wherein the polyolefin is polyethylene, a copolymer of polyethylene, or combinations thereof. Methods of forming crosslinked polyolefin nanocomposites, the polyolefin nanocomposite precursor compositions, and crosslinked polyolefin nanocomposites are also provided.

Abstract: The present disclosure provides a compact bionic eye device based on a two-degree-of-freedom electromagnetically-driven rotating mechanism, which can be used as a vision sensor of bionic robots such as humanoid robots. The compact bionic eye device includes a rotor, stator cores, windings, an angular displacement camera, a spherical hinge pressing block, a stator connector, a camera, a spherical hinge, a camera connector, a rotor connector and an outer spherical shell. According to the compact bionic eye device of the present disclosure, the rotor is driven to achieve limited rotation with pitching and yawing degrees of freedom by regulating a current of the windings of four stators. By adopting a two-degree-of-freedom of electromagnetically-driven rotating mechanism which is compact in structure, the bionic eye device of the present disclosure can achieve a human eye size, and provides important foundation for practical application of bionic eyes in humanoid robots.

Abstract: Methods for forming polyolefin nanocomposite precursor compositions are provided. In embodiments, such a method comprises mixing a polyolefin, unmodified graphite, and a peroxide crosslinker via solid-state shear polymerization under conditions to form a polyolefin nanocomposite precursor composition comprising the polyolefin; exfoliated, unmodified graphite dispersed throughout the polyolefin; and unreacted peroxide crosslinker dispersed throughout the polyolefin, wherein the polyolefin is polyethylene, a copolymer of polyethylene, or combinations thereof. Methods of forming crosslinked polyolefin nanocomposites, the polyolefin nanocomposite precursor compositions, and crosslinked polyolefin nanocomposites are also provided.

Abstract: Disclosed herein is a system comprising: a networking device, a storage, and a proxy server, wherein the proxy server is configured to identify a first group of contents from first data received from a content server, to modify the first data to generate second data by replacing the first group of contents with labels, and to transmit the second data to the networking device; wherein the networking device is configured to read the labels in the second data, to request contents from the storage based on the labels, to replace the labels with the contents received from the storage to generate third data, to transmit the third data to a mobile device.

Abstract: The present invention discloses method for preparing deoxycholic acid (DCA) or an ester thereof or a pharmaceutically acceptable salt thereof. Said compounds may be applied to remove a fat deposition.

Abstract: The present invention discloses method for preparing deoxycholic acid (DCA) or an ester thereof or a pharmaceutically acceptable salt thereof. Said compounds may be applied to remove a fat deposition.

Abstract: Disclosed herein is a system comprising: a networking device, a storage, and a proxy server, wherein the proxy server is configured to identify a first group of contents from first data received from a content server, to modify the first data to generate second data by replacing the first group of contents with labels, and to transmit the second data to the networking device; wherein the networking device is configured to read the labels in the second data, to request contents from the storage based on the labels, to replace the labels with the contents received from the storage to generate third data, to transmit the third data to a mobile device.

Abstract: The present invention discloses method for preparing deoxycholic acid (DCA) or an ester thereof or a pharmaceutically acceptable salt thereof. Said compounds may be applied to remove a fat deposition.

Abstract: The present invention discloses a polycarbonate composition, which includes the following components in parts by weight: a. 30-80 parts of a polycarbonate; b. 8-50 parts of a graft copolymer; c. 5-25 parts of a fire retardant; and d. 0-10 parts of other aids; wherein a sum of parts by weight of the four components a, b, c, and d is 100. A long-term thermal-oxidative aging property and a weathering property of the polycarbonate composition can be significantly improved when a total compounding amount of a transition element and an alkaline earth metal, which are added in a polycarbonate composition formula, based on a total weight of the polycarbonate composition is greater than or equal to 10 ppm and less than or equal to 600 ppm and a compounding molar ratio of the transition element to the alkaline earth metal is adjusted to 0.1-1; and the polycarbonate composition is particularly suitable for occasions with relatively high requirements for an operating environment.

Abstract: Aspects of the disclosure provide a circuit that can include a depletion mode transistor coupled to a power source and a current path coupled with the depletion mode transistor in series to provide a current to charge a capacitor. Further, a gate terminal of the depletion mode transistor is coupled to a clamping path that includes a diode and a switch that connected in series. The clamping path clamps the voltage at the gate terminal of the depletion mode transistor to the capacitor. The clamping and the current paths respectively have a first resistance during a first stage, such as when the circuit initially receives power, and have a second resistance during a second stage when the capacitor is charged to have a predetermined voltage level.

Abstract: Computer-aided diagnosis techniques may be combined with techniques to obtain derived images from radiographic images to provide enhanced computer-aided diagnosis of, for example, lung nodules.

Abstract: Computer-aided diagnosis techniques may be combined with techniques to obtain derived images from radiographic images to provide enhanced computer-aided diagnosis of, for example, lung nodules.

Abstract: Computer-aided diagnosis techniques may be combined with dual-energy radiography techniques to provide enhanced computer-aided diagnosis of, for example, lung nodules.

Abstract: Computer-aided diagnosis techniques may be combined with dual-energy radiography techniques to provide enhanced computer-aided diagnosis of, for example, lung nodules.

Abstract: A substrate cassette having a conventional form, an open container having an upper entrance and a narrow lower opening formed by two side panels and two end panels. A preferred embodiment includes a train of substrate alignment channels on the inner surfaces of the two side panels, each channel is U shaped and having planar surface with a left surface, a right surface, and a bottom surface. An arcuate curbing member disposed on a left surface in each of the substrate alignment channels. The arcuate curbing member includes a top end with a thinner sloped profile facing the upper open entrance of the cassette allowing a substrate to slide through and under a stepped lower end.