Patents by Inventor Tony Triglia

Tony Triglia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIMALARIAL AGENTS
    Publication number: 20230139282
    Abstract: Provided are methods of treating malaria comprising administration of compounds of Formula (I) or a pharmaceutically acceptable salt thereof, to a subject in need thereof, wherein the variables are as defined herein. Also provided are uses of the compounds of Formula (I), as defined herein, for treating a Plasmodium infection, and for treating malaria. Also provided are methods of treatment further comprising administration of one or more additional anti-malarial compounds.
    Type: Application
    Filed: February 2, 2021
    Publication date: May 4, 2023
    Applicants: Merck Sharp & Dohme LLC, The Walter and Eliza Hall Institute of Medical Research, MSD R&D (China) Co., Ltd.
    Inventors: Manuel de Lera Ruiz, Paola Favuzza, Zhuyan Guo, Bin Hu, Michael J. Kelly, III, Zhiyu Lei, John A. McCauley, David B. Olsen, Brad Sleebs, Tony Triglia, Dongmei Zhan, Lianyun Zhao
  • ANTIMALARIAL AGENTS
    Publication number: 20220331321
    Abstract: Methods of treating malaria comprising administration of compounds of Formula (I?) or a pharmaceutically acceptable salt thereof, to a subject in need thereof, wherein the variables are as defined herein. It also provides uses of the compounds of Formula (I), as defined herein, for inhibiting plasmepsin X, plasmepsin IX or plasmepsin X and IX activity, for treating a Plasmodium infection, and for treating malaria. Also provided are methods of treatment further comprising administration of one or more additional anti-malarial compounds.
    Type: Application
    Filed: July 21, 2020
    Publication date: October 20, 2022
    Applicants: Merck Sharp & Dohme Corp., The Walter and Eliza Hall Institute of Medical Research, MSD R & D (China) Co. LTD.
    Inventors: John A. McCauley, Alan F. Cowman, Manuel de Lera Ruiz, Paola Favuzza, Zhuyan Guo, Bin Hu, Michael J. Kelly, III, Zhiyu Lei, David B. Olsen, Brad Sleebs, Jennifer K. Thompson, Tony Triglia, Dongmei Zhan, Cailing Zhang, Lianyun Zhao
  • Treatment and prevention of malaria
    Patent number: 9884101
    Abstract: The present invention relates to recombinant fragments of Plasmodium polypeptides and polynucleotides encoding same. The invention further relates to compositions comprising the recombinant fragments of Plasmodium polypeptides and their use in the treatment and prevention of malaria.
    Type: Grant
    Filed: July 30, 2015
    Date of Patent: February 6, 2018
    Assignee: The Walter and Eliza Hall Institute for Medical Research
    Inventors: Lin Chen, Alan Cowman, Tony Triglia
  • TREATMENT AND PREVENTION OF MALARIA
    Publication number: 20150366958
    Abstract: The present invention relates to recombinant fragments of Plasmodium polypeptides and polynucleotides encoding same. The invention further relates to compositions comprising the recombinant fragments of Plasmodium polypeptides and their use in the treatment and prevention of malaria.
    Type: Application
    Filed: July 30, 2015
    Publication date: December 24, 2015
    Inventors: Lin Chen, Alan Cowman, Tony Triglia
  • Treatment and prevention of malaria
    Patent number: 9109040
    Abstract: The present invention relates to polypeptides from Plasmodium and polynucleotides encoding the polypeptides. The invention further relates to compositions comprising the polypeptides and their use in the treatment and prevention of malaria.
    Type: Grant
    Filed: November 8, 2011
    Date of Patent: August 18, 2015
    Assignee: The Walter and Eliza Hall Institute of Medical Research
    Inventors: Lin Chen, Alan Cowman, Tony Triglia
  • TREATMENT AND PREVENTION OF MALARIA
    Publication number: 20140010816
    Abstract: The present invention relates to polypeptides from Plasmodium and polynucleotides encoding the polypeptides. The invention further relates to compositions comprising the polypeptides and their use in the treatment and prevention of malaria.
    Type: Application
    Filed: November 8, 2011
    Publication date: January 9, 2014
    Inventors: Lin Chen, Alan Cowman, Tony Triglia