Patents by Inventor Toshihiro Aoki
Toshihiro Aoki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240136181Abstract: A semiconductor substrate includes a support substrate, a mask pattern located above the support substrate and including a mask portion, a seed portion locally located in a layer above the support substrate in a plan view, and a semiconductor part including a GaN-based semiconductor and located above the mask pattern to be in contact with the seed portion and the mask portion.Type: ApplicationFiled: February 24, 2022Publication date: April 25, 2024Applicant: KYOCERA CorporationInventors: Katsuaki MASAKI, Takeshi KAMIKAWA, Toshihiro KOBAYASHI, Yuichiro HAYASHI, Yuta AOKI
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Patent number: 11964950Abstract: The present disclosure provides, for example, a compound represented by the general formula below or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of the compound or salt: wherein X1, X2, X3 and X4 are each independently —CR2? or N?, R2 is, for example, a halogen atom, R1 is, for example, —S(?O)2—NH—R8, R8 is, for example, a C1-6 alkyl group, R3 is, for example, a hydrogen atom, R5 is, for example, a halogen atom, R6 is, for example, a hydrogen atom, and R4 is, for example, a cyclopropyl group. The compounds, salts or solvates provided by the present disclosure exhibit high RAF/MEK complex-stabilizing activity and can be used for the treatment or prevention of cell proliferative disorders, particularly cancers.Type: GrantFiled: July 20, 2022Date of Patent: April 23, 2024Assignee: Chugai Seiyaku Kabushiki KaishaInventors: Yoshiaki Isshiki, Fumio Watanabe, Masaki Tomizawa, Kihito Hada, Kazuo Hattori, Kenichi Kawasaki, Ikumi Hyodo, Toshihiro Aoki
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Publication number: 20240127471Abstract: An information processing apparatus according to an embodiment of the present disclosure processes information about a position of an object moved by a mobile object, and includes an output unit configured to output the information about the position of the object. The information about the position of the object is obtained based on holding information indicating whether the object is held or not held by the mobile object and information about a position of the mobile object. The information about the position of the mobile object is obtained based on a captured image captured by an imaging device.Type: ApplicationFiled: January 13, 2022Publication date: April 18, 2024Inventors: Toshihiro OKAMOTO, Shin AOKI, Sukehiro KIMURA, Kenji NAGASHIMA, Toshiyuki IKEOH, Soichiro YOKOTA
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Publication number: 20230002333Abstract: The present disclosure provides, for example, a compound represented by general formula (6) below or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of the compound or salt: wherein X1, X2, X3 and X4 are each independently —CR2? or —N?, R2 is, for example, a halogen atom, R1 is, for example, —S(?O)2—NH—R8, R8 is, for example, a C1-6 alkyl group, R3 is, for example, a hydrogen atom, R5 is, for example, a halogen atom, R6 is, for example, a hydrogen atom, and R4 is, for example, a cyclopropyl group. The compounds, salts or solvates provided by the present disclosure exhibit high RAF/MEK complex-stabilizing activity and can be used for the treatment or prevention of cell proliferative disorders, particularly cancers.Type: ApplicationFiled: July 20, 2022Publication date: January 5, 2023Applicant: Chugai Seiyaku Kabushiki KaishaInventors: Yoshiaki Isshiki, Fumio Watanabe, Masaki Tomizawa, Kihito Hada, Kazuo Hattori, Kenichi Kawasaki, Ikumi Hyodo, Toshihiro Aoki
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Patent number: 10479780Abstract: An objective of the present invention is to provide low-molecular-weight compounds that can inhibit Src family kinases. The present invention relates to compounds represented by general formula (I) or pharmacologically acceptable salts thereof. In the formula, Ar1 is optionally substituted C6-10 arylene or 5- to 10-membered heteroarylene, and Ar2 is optionally substituted C6-10 aryl or 5- to 10-membered heteroaryl. R1 and R2 are defined as described in the specification.Type: GrantFiled: June 17, 2016Date of Patent: November 19, 2019Assignees: Chugai Seiyaku Kabushiki Kaisha, F. Hoffmann-La Roche AGInventors: Hirosato Ebiike, Toshihiro Aoki, Takashi Chiba, Masami Kochi, Kimitaka Nakama, Satoshi Niizuma, Hiroki Nishii, Jun Ohwada, Hiroyuki Shimamura, Aiko Suge, Yoshito Nakanishi, Natsuki Kobayashi
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Publication number: 20180362509Abstract: An objective of the present invention is to provide low-molecular-weight compounds that can inhibit Src family kinases. The present invention relates to compounds represented by general formula (I) or pharmacologically acceptable salts thereof. In the formula, Ar1 is optionally substituted C6-10 arylene or 5- to 10-membered heteroarylene, and Ar2 is optionally substituted C6-10 aryl or 5- to 10-membered heteroaryl. R1 and R2 are defined as described in the specification.Type: ApplicationFiled: June 17, 2016Publication date: December 20, 2018Applicants: Chugai Seiyaku Kabushiki Kaisha, F. Hoffmann-La Roche AGInventors: Hirosato Ebiike, Toshihiro Aoki, Takashi Chiba, Masami Kochi, Kimitaka Nakama, Satoshi Niizuma, Hiroki Nishii, Jun Ohwada, Hiroyuki Shimamura, Aiko Suge, Yoshito Nakanishi, Natsuki Kobayashi
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Patent number: 8569378Abstract: The present invention provides a p27 protein inducing agent comprising a compound represented by general formula (11) below or pharmaceutically acceptable salt thereof as an active ingredient: wherein G1, G2, G3 and G8 are each independently selected from —N? etc., Ring G6 is selected from divalent aryl etc., A is selected from amino etc., G4 is selected from oxygen etc., G5 is selected from oxygen etc., G7 is selected from —CH2— etc., and R2 is selected from C1-6 alkyl etc.Type: GrantFiled: July 18, 2008Date of Patent: October 29, 2013Assignees: Chugai Seiyaku Kabushiki KaishaInventors: Toshiyuki Sakai, Hitoshi Iikura, Ikumi Hyoudoh, Toshihiro Aoki, Noriyuki Furuichi, Masayuki Matsushita, Fumio Watanabe, Sawako Ozawa, Masahiro Sakaitani, Pil-Su Ho, Yasushi Tomii, Kenji Takanashi, Naoki Harada
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Patent number: 8278465Abstract: The present invention provides a compound represented by general formula (1) below or a pharmaceutically acceptable salt thereof: wherein: X is selected from heteroaryl etc., Y1 and Y2 are selected from —N? etc., Y3 and Y4 are selected from —CH? etc., A is selected from sulfamide etc., R1 is selected from hydrogen etc., and R2 is selected from C1-6 alkyl etc. The compound or salt has sufficiently high antitumor activity, and is useful in the treatment of cell proliferative disorders, particularly cancers. The present invention also provides a pharmaceutical composition containing the compound or salt as an active ingredient.Type: GrantFiled: December 3, 2010Date of Patent: October 2, 2012Assignees: Chugai Seiyaku Kabushiki Kaisha, Sakai ToshiyukiInventors: Hitoshi Iikura, Ikumi Hyoudoh, Toshihiro Aoki, Noriyuki Furuichi, Masayuki Matsushita, Fumio Watanabe, Sawako Ozawa, Masahiro Sakaitani, Pil-Su Ho, Yasushi Tomii, Kenji Takanashi, Naoki Harada
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Publication number: 20110092700Abstract: The present invention provides a compound represented by general formula (1) below or a pharmaceutically acceptable salt thereof: wherein: X is selected from heteroaryl etc., Y1 and Y2 are selected from —N? etc., Y3 and Y4 are selected from —CH? etc., A is selected from sulfamide etc., R1 is selected from hydrogen etc., and R2 is selected from C1-6 alkyl etc. The compound or salt has sufficiently high antitumor activity, and is useful in the treatment of cell proliferative disorders, particularly cancers. The present invention also provides a pharmaceutical composition containing the compound or salt as an active ingredient.Type: ApplicationFiled: December 3, 2010Publication date: April 21, 2011Inventors: Hitoshi Iikura, Ikumi Hyoudoh, Toshihiro Aoki, Noriyuki Furuichi, Masayuki Matsushita, Fumio Watanabe, Sawako Ozawa, Masahiro Sakaitani, Pil-Su Ho, Yasushi Tomii, Kenji Takanashi, Naoki Harada
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Patent number: 7897792Abstract: The present invention provides a compound represented by general formula (1) below or a pharmaceutically acceptable salt thereof: wherein: X is selected from heteroaryl etc., Y1 and Y2 are selected from —N? etc., Y3 and Y4 are selected from —CH? etc., A is selected from sulfamide etc., R1 is selected from hydrogen etc., and R2 is selected from C1-6 alkyl etc. The compound or salt has sufficiently high antitumor activity, and is useful in the treatment of cell proliferative disorders, particularly cancers. The present invention also provides a pharmaceutical composition containing the compound or salt as an active ingredient.Type: GrantFiled: February 9, 2007Date of Patent: March 1, 2011Assignees: Chugai Seiyaku Kabushiki KaishaInventors: Hitoshi Iikura, Ikumi Hyoudoh, Toshihiro Aoki, Noriyuki Furuichi, Masayuki Matsushita, Fumio Watanabe, Sawako Ozawa, Masahiro Sakaitani, Pil-Su Ho, Yasushi Tomii, Kenji Takanashi, Naoki Harada
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Publication number: 20110009398Abstract: The present invention provides a p27 protein inducing agent comprising a compound represented by general formula (11) below or pharmaceutically acceptable salt thereof as an active ingredient: wherein G1, G2, G3 and G8 are each independently selected from —N? etc., Ring G6 is selected from divalent aryl etc., A is selected from amino etc., G4 is selected from oxygen etc., G5 is selected from oxygen etc., G7 is selected from —CH2— etc., and R2 is selected from C1-6 alkyl etc.Type: ApplicationFiled: July 18, 2008Publication date: January 13, 2011Inventors: Toshiyuki Sakai, Hitoshi Iikura, Ikumi Hyoudoh, Toshihiro Aoki, Noriyuki Furuichi, Masayuki Matsushita, Fumio Watanabe, Sawako Ozawa, Masahiro Sakaitani, Pil-Su Ho, Yasushi Tomii, Kenji Takanashi, Naoki Harada
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Publication number: 20100004233Abstract: The present invention provides a compound represented by general formula (1) below or a pharmaceutically acceptable salt thereof: wherein: X is selected from heteroaryl etc., Y1 and Y2 are selected from —N? etc., Y3 and Y4 are selected from —CH? etc., A is selected from sulfamide etc., R1 is selected from hydrogen etc., and R2 is selected from C1-6 alkyl etc. The compound or salt has sufficiently high antitumor activity, and is useful in the treatment of cell proliferative disorders, particularly cancers. The present invention also provides a pharmaceutical composition containing the compound or salt as an active ingredient.Type: ApplicationFiled: February 9, 2007Publication date: January 7, 2010Inventors: Hitoshi Iikura, Ikumi Hyoudoh, Toshihiro Aoki, Noriyuki Furuichi, Masayuki Matsushita, Fumio Watanabe, Sawako Ozawa, Masahiro Sakaitani, Pil-Su Ho, Yasushi Tomii, Kenji Takanashi, Naoki Harada
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Patent number: 7639322Abstract: A liquid crystal display device includes a first substrate having a plurality of first electrodes, a second substrate facing the first substrate and having a plurality of second electrodes perpendicular to the first electrodes to define sub-pixels at intersection regions between the first and second electrodes, a liquid crystal layer between the first and second substrates, a plurality of color filters between the first and second substrates adapted to correspond to respective sub-pixels, the color filters including first color filters and second color filters having a different shape than the first color filters, a black matrix between the color filters, the black matrix including vertical portions, horizontal portions, and step portions, each of the step portions corresponding to a respective second color filter, and a plurality of patterned spacers between the first and second substrates, each of the patterned spacers overlaps with a respective step-portion of the black matrix.Type: GrantFiled: January 18, 2008Date of Patent: December 29, 2009Assignee: Samsung Mobile Display Co., Ltd.Inventors: Dong-soo Son, Seo-hee Ha, Sung-ku Kang, Jong-su Lee, Toshihiro Aoki, Jai-sang Jung
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Patent number: 5126868Abstract: A display cell is mounted on a color-compensating cell. The display cell has a pair of substrates each having an alignment-treated surface, a first liquid-crystal layer and electrodes. Multiplex drive signals are supplied to the electrodes. The color-compensating cell has a second liquid-crystal layer. The molecules of the first liquid-crystal layer are twisted by a twist angle ranging from 160.degree. to 270.degree.. The molecules of the second liquid-crystal layer are twisted by the same angle in the opposite direction. The substrates are alignment-treated in two directions, respectively, which are substantially at right angles to each other. One of the polarizing plates has an optical axis crossing at 35.degree. to 50.degree. with an aligning direction of the liquid crystal molecules on that substrate adjacent to the polarizing plate, and crossing with the optical axis of the other polarizing plate at right angles.Type: GrantFiled: December 22, 1989Date of Patent: June 30, 1992Assignee: Casio Computer Co., Ltd.Inventors: Seiichi Kizaki, Toshiomi Ono, Ken Kozima, Mikiya Itakura, Toshihiro Aoki
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Patent number: 5008166Abstract: A method of manufacturing color filters in which a photosensitive film, which is used for forming filter elements, is formed on a substrate. A photomask with a given stripe pattern is placed above the photoresistive film. Under this condition, the photomasked-film is subjected to a first exposure process. The photomask is then moved in the direction of the stripes in the mask pattern. Following a second exposure process, developing, dyeing and dyeing-preventing processes are performed for color filter element formation. The foregoing steps are performed for each filter element for a specified color.Type: GrantFiled: November 8, 1989Date of Patent: April 16, 1991Assignee: Casio Computer Co., Ltd.Inventor: Toshihiro Aoki
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Patent number: 4925295Abstract: A projection display apparatus includes a light source unit for generating light for image formation, an electro-optical display device for displaying an optical image by utilizing the light emitted from the light source unit, and an enlarging/projection lens. The light source unit, the display device, and the projection lens are accommodated in a housing with vent openings. The housing also includes a fan for cooling the interior of the housing with cool air and a cooler for maintaining a display panel within a predetermined temperature range. The light source unit includes a lamp and a reflector and is designed not to cause image deformation and formation of a shadow of a discharge portion. In order to display a television image on the display device, all television image display circuit units excluding an antenna are accommodated in the housing. The enlarging/projection lens can control a magnification and a focal point of the image projected on the screen.Type: GrantFiled: September 14, 1988Date of Patent: May 15, 1990Assignee: Casio Computer Co., Ltd.Inventors: Masahiro Ogawa, Tatsuo Shimazaki, Osamu Umeda, Toshihiro Aoki, Toru Nakakusu
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Patent number: 4427816Abstract: Stabilizer compositions for halogen-containing polymers are provided composed of a .beta.-diketone as well as metal and organotin enolate salts thereof; and a hydrotalcite having the general formula:Mg.sub.1-x Al.sub.x (OH).sub.2 A.sub.x/2.mH.sub.2 Owhereinx is a number from 0 to 0.5;A is CO.sub.3.sup.= or SO.sub.4.sup.=, andm is a number representing the number of H.sub.2 O in the molecule.The stabilizer compositions are effective in enhancing the resistance to deterioration by heat and light of halogen-containing polymers and especially polyvinyl halide resins. The .beta.-diketone and hydrotalcite in these compositions exhibit a synergistic stabilizing effectiveness superior to either alone in like amount.Type: GrantFiled: January 29, 1982Date of Patent: January 24, 1984Assignee: Adeka Argus Chemical Co., Ltd.Inventors: Toshihiro Aoki, Yoshio Iida