Abstract: Provided is a medicinal composition having excellent stability, the medicinal composition comprising 3-{[(2S)-2-amino-2-carboxyethyl]carbamoylamino}-5-chloro-4-methylbenzenesulfonic acid, a pharmaceutically acceptable salt thereof, or a solvate thereof, wherein the medicinal composition has a pH of 8.0 or less.

Abstract: A medicinal composition for preventing or treating secondary hyperparathyroidism under maintenance dialysis, said medicinal composition comprising 3-{[(2S)-2-amino-2-carboxyethyl]carmaboylamino}-5-chloro-4-methylbenzenesulfonic acid or a pharmaceutically acceptable salt thereof, or a solvate of the same which is to be administered by a predefined route in a predefined dosage. According to the present invention, it is possible to provide a prophylactic or therapeutic agent for secondary hyperparathyroidism under maintenance dialysis, said agent showing reduced side effects or no significant accumulation. This medicinal agent allows easy administration management and has a high safety compared with conventional products.

Abstract: A medicinal composition for preventing or treating secondary hyperparathyroidism under maintenance dialysis, said medicinal composition comprising 3-{[(2S)-2-amino-2-carboxyethyl]carmaboylamino}-5-chloro-4-methylbenzenesulfonic acid or a pharmaceutically acceptable salt thereof, or a solvate of the same which is to be administered by a predefined route in a predefined dosage. According to the present invention, it is possible to provide a prophylactic or therapeutic agent for secondary hyperparathyroidism under maintenance dialysis, said agent showing reduced side effects or no significant accumulation. This medicinal agent allows easy administration management and has a high safety compared with conventional products.

Abstract: Provided is a sulfonamide derivative represented by the following general formula (1) and having an ?4 integrin inhibitory effect with high selectivity with a low effect on ?4?1 and a high effect on ?4?7, or a pharmaceutically acceptable salt thereof (in the general formula (1), A, B, D, E, R41, and a to h are as described in the description).

Abstract: A pressure sensor is provided, which includes a pressure detector that has a pressure receiving surface in contact with a liquid, and detects a pressure of the liquid to a pressure receiving section, and a housing having a housing inner wall that demarcates a liquid chamber, wherein the housing inner wall is provided with an inflow hole, and an outflow hole, at least a part of a connecting portion, which is connected to the pressure receiving surface, of the housing inner wall is formed as an inner wall of the outflow hole, and the housing inner wall at the portion formed as the inner wall of the outflow hole protrudes more outward of the liquid chamber than the other connecting portion adjacent to the portion formed as the inner wall of the outflow hole.

Abstract: A plug structure for taking out liquid from a container includes a plug body press-fitted into a container inlet port. The plug body is resiliently deformable with a lower portion being formed into a ring shape and being provided with slits in an axial direction. The plug structure includes a locking claw on an outer peripheral surface of the plug body, which projects toward an inner wall surface of the container inlet port. The locking claw has a minimum diameter substantially the same as or smaller than the inner diameter of the container inlet port. The locking claw has a maximum diameter that is larger than the inner diameter of the container inlet port. The plug structure includes a valve operating portion that presses a valve on a socket connected to the plug body. The valve operating portion is provided on an upper end inlet port of the siphon tube.

Abstract: Provided is a sulfonamide derivative represented by the following general formula (1) and having an ?4 integrin inhibitory effect with high selectivity with a low effect on ?4?1 and a high effect on ?4?7, or a pharmaceutically acceptable salt thereof (in the general formula (1), A, B, D, E, R41, and a to h are as described in the description).

Abstract: An amplifier-embedded pressure sensor includes: a pressure-detecting element which detects the differential pressure between the fluid and the space where the pipe including a fluid passage of the fluid is installed, and outputs the pressure signal; an amplifier circuit board having an amplifier circuit for amplifying the pressure signal; a housing to which the pressure-detecting element is fixed; and a separation part which is fixed to the housing and separates a space inside the housing into a first space where the pressure-detecting element is disposed and a second space where the amplifier circuit board is disposed. The housing includes an inflow port for letting cooling gas for cooling the amplifier circuit board flow into the second space and a discharge port for discharging the cooling gas from the second space.

Abstract: Provided are a joining portion in which a male threaded portion threaded to a container-side female threaded portion is formed; a connector main unit disposed at an inner side of the joining portion, sharing a center axis therewith, and is connected so as to be rotatable relative thereto; and a siphon tube attached to the connector main unit so as to extend toward the bottom portion of the container and has a tip curved in a substantially horizontal direction, wherein the joining portion is screwed in independently of the connector main unit when attaching the connector by using a securing jig that, by being inserted from above the connector main unit, causes depressed/protruding portions to be engaged, thus preventing relative rotation to each other, and by using a tightening jig that tightens the male threaded portion by being engaged at the upper surface of the joining portion.

Abstract: Provided is a socket structure capable of preventing or inhibiting defective attachment/detachment thereof and defective movement and defective sealing of a valve mechanism due to a solid deposit caused by a fluid. A socket used by connecting the socket to a plug of a connector includes a socket body in which a channel is formed and which has a valve mechanism; and a sleeve which is disposed so as to be slidable in an axial direction thereof and rotatable along an outer circumferential surface of the socket body. The socket is configured to be screwed and secured by inserting and connecting an entrance of the channel that opens at a lower end of the socket body to a plug exit that opens at an upper end of the plug and then a sleeve thread portion is screwed into a socket female thread portion by rotating the sleeve.

Abstract: A pressure sensor is provided, which includes a pressure detector that has a pressure receiving surface in contact with a liquid, and detects a pressure of the liquid to a pressure receiving section, and a housing having a housing inner wall that demarcates a liquid chamber, wherein the housing inner wall is provided with an inflow hole, and an outflow hole, at least a part of a connecting portion, which is connected to the pressure receiving surface, of the housing inner wall is formed as an inner wall of the outflow hole, and the housing inner wall at the portion formed as the inner wall of the outflow hole protrudes more outward of the liquid chamber than the other connecting portion adjacent to the portion formed as the inner wall of the outflow hole.

Abstract: A plug structure for taking out liquid from a container includes a plug body press-fitted into a container inlet port. The plug body is resiliently deformable with a lower portion being formed into a ring shape and being provided with slits in an axial direction. The plug structure includes a locking claw on an outer peripheral surface of the plug body, which projects toward an inner wall surface of the container inlet port. The locking claw has a minimum diameter substantially the same as or smaller than the inner diameter of the container inlet port. The locking claw has a maximum diameter that is larger than the inner diameter of the container inlet port. The plug structure includes a valve operating portion that presses a valve on a socket connected to the plug body. The valve operating portion is provided on an upper end inlet port of the siphon tube.

Abstract: A plug structure is provided that can be installed on a container in which the thread of a container inlet for installing a cap is an outer thread, and furthermore, bubbles are not produced at the fluid surface inside the container even during fluid circulation. In a plug structure that is used in a container in which the thread of the container inlet for attaching the cap is an external thread, that is installed on the container inlet, that is capable of removing a fluid inside the container by using the siphon hose method, and that is capable of circulating the fluid that is inside the container, a fluid circulation path is provided that causes a fluid that is returning into the container during fluid circulation to fall along an external wall of a siphon hose during fluid removal.

Abstract: A plug structure which allows attachment to a container whose cap attachment screw at the container inlet port is an outer screw is provided. There is provided a plug structure used for a container whose cap attachment screw of a container inlet port is an outer screw, configured to be attached to the container inlet port, and provided with a siphon tube for taking out liquid in the interior of the container including a plug body to be press-fitted into the container inlet port being resiliently deformable in a radial direction at a lower portion thereof, and a locking claw provided on an outer peripheral surface of the lower portion of the plug body so as to project toward an inner wall surface of the container inlet port.

Abstract: An amplifier-embedded pressure sensor includes: a pressure-detecting element which detects the differential pressure between the fluid and the space where the pipe including a fluid passage of the fluid is installed, and outputs the pressure signal; an amplifier circuit board having an amplifier circuit for amplifying the pressure signal; a housing to which the pressure-detecting element is fixed; and a separation part which is fixed to the housing and separates a space inside the housing into a first space where the pressure-detecting element is disposed and a second space where the amplifier circuit board is disposed. The housing includes an inflow port for letting cooling gas for cooling the amplifier circuit board flow into the second space and a discharge port for discharging the cooling gas from the second space.

Abstract: A fluid tank connector enables reliable separation of a plug and a socket by opposing the coupling force of a fluid sealing portion. The fluid tank connector is provided with a plug that is fit with play in the inner periphery of a fluid port of the fluid tank that stores a fluid, and a socket that is detachably connectable to the plug. The socket includes a sleeve that connects and disconnects the socket and the plug by being threadable on an external thread that is formed on the outer periphery of the fluid port. A pressing device is provided in the socket, and the pressing device applies a pressing force that separates the plug from the socket by opposing the coupling force of an O-ring that seals the fluid path between the plug and the socket.

Abstract: Provided are a joining portion in which a male threaded portion threaded to a container-side female threaded portion is formed; a connector main unit disposed at an inner side of the joining portion, sharing a center axis therewith, and is connected so as to be rotatable relative thereto; and a siphon tube attached to the connector main unit so as to extend toward the bottom portion of the container and has a tip curved in a substantially horizontal direction, wherein the joining portion is screwed in independently of the connector main unit when attaching the connector by using a securing jig that, by being inserted from above the connector main unit, causes depressed/protruding portions to be engaged, thus preventing relative rotation to each other, and by using a tightening jig that tightens the male threaded portion by being engaged at the upper surface of the joining portion.

Abstract: A liquid tank connector for preventing leakage of contents in a liquid tank when removing a socket from a plug fixed to the liquid tank is provided. The liquid tank connector which includes a plug to be fixed to a liquid tank where liquid is stored, a socket which is able to be connected and disconnected with respect to the plug, and a sleeve for releasing a connected state between the plug and the socket by a relative movement with respect to the socket, and in which a liquid flow channels and gas flow channels are formed in a liquid deliverable state in which the plug and the socket are connected, and which includes: a cock which forms a gas flow channel in the liquid deliverable state, and the relative movement of the sleeve is controlled by the position of the cock in the liquid deliverable state.

Abstract: Provided is a socket structure capable of preventing or inhibiting defective attachment/detachment thereof and defective movement and defective sealing of a valve mechanism due to a solid deposit caused by a fluid. A socket used by connecting the socket to a plug of a connector includes a socket body in which a channel is formed and which has a valve mechanism; and a sleeve which is disposed so as to be slidable in an axial direction thereof and rotatable along an outer circumferential surface of the socket body. The socket is configured to be screwed and secured by inserting and connecting an entrance of the channel that opens at a lower end of the socket body to a plug exit that opens at an upper end of the plug and then a sleeve thread portion is screwed into a socket female thread portion by rotating the sleeve.

Abstract: A plug structure which allows attachment to a container whose cap attachment screw at the container inlet port is an outer screw is provided. There is provided a plug structure used for a container whose cap attachment screw of a container inlet port is an outer screw, configured to be attached to the container inlet port, and provided with a siphon tube for taking out liquid in the interior of the container including a plug body to be press-fitted into the container inlet port being resiliently deformable in a radial direction at a lower portion thereof, and a locking claw provided on an outer peripheral surface of the lower portion of the plug body so as to project toward an inner wall surface of the container inlet port.