Patents by Inventor Travis B. White

Travis B. White has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of template switching for DNA synthesis
    Patent number: 9012183
    Abstract: A method of preparing a DNA copy of a target polynucleotide using template switching is described. The method includes mixing a double stranded template/primer substrate made up of a DNA primer oligonucleotide associated with a complementary oligonucleotide template strand with a target polynucleotide in a reaction medium and adding a suitable amount of a non-retroviral reverse transcriptase to the reaction medium to extend the DNA primer oligonucleotide from its 3? end to provide a DNA copy polynucleotide. The DNA copy polynucleotide includes a complementary target DNA polynucleotide that is synthesized using the target polynucleotide as a template. Methods of adding nucleotides to the double stranded template/primer substrate are also described. The method can be used to facilitate detection, PCR amplification, cloning, and determination of RNA and DNA sequences.
    Type: Grant
    Filed: February 23, 2012
    Date of Patent: April 21, 2015
    Assignee: Board of Regents, The University of Texas System
    Inventors: Alan M. Lambowitz, Sabine Mohr, Travis B. White, Scott Kuersten
  • USE OF TEMPLATE SWITCHING FOR DNA SYNTHESIS
    Publication number: 20140004569
    Abstract: A method of preparing a DNA copy of a target polynucleotide using template switching is described. The method includes mixing a double stranded template/primer substrate made up of a DNA primer oligonucleotide associated with a complementary oligonucleotide template strand with a target polynucleotide in a reaction medium and adding a suitable amount of a non-retroviral reverse transcriptase to the reaction medium to extend the DNA primer oligonucleotide from its 3? end to provide a DNA copy polynucleotide. The DNA copy polynucleotide includes a complementary target DNA polynucleotide that is synthesized using the target polynucleotide as a template. Methods of adding nucleotides to the double stranded template/primer substrate are also described. The method can be used to facilitate detection, PCR amplification, cloning, and determination of RNA and DNA sequences.
    Type: Application
    Filed: February 23, 2012
    Publication date: January 2, 2014
    Applicant: Board of Regents, The University of Texas System
    Inventors: Alan M. Lambowitz, Sabine Mohr, Travis B. White, Scott Kuersten