Patents by Inventor Travis C. McGuire

Travis C. McGuire has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neutralization-sensitive epitopes of Cryptosporidium parvum
    Patent number: 6759048
    Abstract: DNA sequences encoding epitopes to which sporozoite-neutralizing antibodies are directed are provided. Recombinant proteins and synthetic peptides containing Cryptosporidium parvum epitopes for inducing an antigenic response are described.
    Type: Grant
    Filed: September 6, 2001
    Date of Patent: July 6, 2004
    Assignees: North Carolina State University, Arizona Board of Regents, Washington State University Regents
    Inventors: Lance E. Perryman, Douglas P. Jasmer, Michael W. Riggs, Travis C. McGuire
  • Nucleic acid vaccines against rickettsial diseases and methods of use
    Publication number: 20040126871
    Abstract: Described are nucleic acid vaccines containing genes to protect animals or humans against rickettsial diseases. Also described are polypeptides and methods of using these polypeptides to detect antibodies to pathogens.
    Type: Application
    Filed: November 24, 2003
    Publication date: July 1, 2004
    Inventors: Anthony F. Barbet, Michael V. Bowie, Roma Reddy Ganta, Michael J. Burridge, Suman M. Mahan, Travis C. McGuire, Fred R. Rurangirwa, Annie L. Moreland, Bigboy H. Simbi, William M. Whitmire, Arthur R. Alleman
  • Nucleic acid vaccines against rickettsial diseases and methods of use
    Patent number: 6653128
    Abstract: Described are nucleic acid vaccines containing genes to protect animals or humans against rickettsial diseases. Also described are polypeptides and methods of using these polypeptides to detect antibodies to pathogens.
    Type: Grant
    Filed: January 31, 2002
    Date of Patent: November 25, 2003
    Assignee: University of Florida
    Inventors: Anthony F. Barbet, Michael V. Bowie, Roman Reddy Ganta, Michael J. Burridge, Suman M. Mahan, Travis C. McGuire, Fred R. Rurangirwa, Annie L. Moreland, Bigboy H. Simbi, William M. Whitmire, Arthur R. Alleman
  • Nucleic acid vaccines against rickettsial diseases and methods of use
    Patent number: 6593147
    Abstract: Described are nucleic acid vaccines containing genes to protect animals or humans against rickettsial diseases. Also described are polypeptides and methods of using these polypeptides to detect antibodies to pathogens.
    Type: Grant
    Filed: April 21, 2000
    Date of Patent: July 15, 2003
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Anthony F. Barbet, Michael V. Bowie, Roman Reddy Ganta, Michael J. Burridge, Suman M. Mahan, Travis C. McGuire, Fred R. Rurangirwa, Annie L. Moreland, Bigboy H. Simbi, William M. Whitmire, Arthur R. Alleman
  • Ehrlichia ruminantium polypeptides, antigens, polynucleotides, and methods of use
    Publication number: 20030044422
    Abstract: Described are nucleic acid vaccines containing genes to protect animals or humans against rickettsial diseases. Also described are polypeptides and methods of using these polypetides to detect antibodies to pathogens.
    Type: Application
    Filed: February 20, 2002
    Publication date: March 6, 2003
    Inventors: Anthony F. Barbet, William M. Whitmire, Sondra M. Kamper, Bigboy H. Simbi, Roman Reddy Ganta, Annie L. Moreland, Duncan M. Mwangi, Travis C. McGuire, Suman M. Mahan
  • Nucleic acid vaccines against rickettsial diseases and methods of use
    Publication number: 20020132789
    Abstract: Described are nucleic acid vaccines containing genes to protect animals or humans against rickettsial diseases. Also described are polypeptides and methods of using these polypeptides to detect antibodies to pathogens.
    Type: Application
    Filed: January 31, 2002
    Publication date: September 19, 2002
    Inventors: Anthony F. Barbet, Michael V. Bowie, Roman Reddy Ganta, Michael J. Burridge, Suman M. Mahan, Travis C. McGuire, Fred R. Rurangirwa, Annie L. Moreland, Bigboy H. Simbi, William M. Whitmire, Arthur R. Alleman
  • Neutralization-sensitive epitopes of Cryptosporidium parvum
    Patent number: 6323020
    Abstract: DNA sequences encoding epitopes to which sporozoite-neutralizing antibodies are directed are provided. Recombinant proteins and synthetic peptides containing Cryptosporidium parvum epitopes for inducing, an antigenic response are described.
    Type: Grant
    Filed: August 22, 1997
    Date of Patent: November 27, 2001
    Assignees: North Carolina State University, Arizona Board of Regents on Behalf of The University of Arizona, Washington State University Research Foundation
    Inventors: Lance E. Perryman, Douglas P. Jasmer, Michael W. Riggs, Travis C. McGuire
  • Nucleic acid vaccines for ehrlichia chaffeensis and methods of use
    Patent number: 6251872
    Abstract: Described are nucleric acid vaccines containing genes to protect animals or humans against Ehrlichia chaffeensis. Also described are polypeptides and methods of using these polypeptides to detect antibodies to pathogens.
    Type: Grant
    Filed: October 17, 1997
    Date of Patent: June 26, 2001
    Assignee: University of Florida
    Inventors: Anthony F. Barbet, Roman Reddy Ganta, Travis C. McGuire, Michael J. Burridge, Aceme Nyika, Fred R. Rurangirwa, Suman M. Mahan, Michael V. Bowie, Arthur Rick Alleman
  • Serological identification of cattle, sheep or goats infected with anaplasma species
    Patent number: 6242571
    Abstract: The subject invention concerns the use of the conserved Anaplasma marginale major surface protein 5 gene and gene product and monoclonal antibody ANAF16C1 for the identification of animals persistently infected with Anaplasma species.
    Type: Grant
    Filed: June 18, 1998
    Date of Patent: June 5, 2001
    Inventors: Donald P. Knowles, Travis C. McGuire, Guy H. Palmer, William C. Davis, Terry F. McElwain
  • Serological identification of cattle, sheep or goats infected with anaplasma species
    Patent number: 5798219
    Abstract: The subject invention concerns the use of monoclonal antibody ANAF16C1 and Anaplasma species major surface protein-5 in the competitive inhibition format for the serological identification of animals infected with Anaplasma species.
    Type: Grant
    Filed: October 16, 1996
    Date of Patent: August 25, 1998
    Assignees: The United States of America as represented by the Secretary of Agriculture, Washington State University Research Foundation
    Inventors: Donald P. Knowles, Travis C. McGuire, Guy H. Palmer, William C. Davis, Terry F. McElwain
  • Immunogenic anaplasma marginale surface antigens, compositions, and methods of use
    Patent number: 5549898
    Abstract: A purified antigenic surface protein of Anaplasma marginale has been identified, and is capable of inducing immune responses in ruminants which neutralizes virulent Anaplasma marginale. The antigenic surface protein has a molecular weight of about 105,000 daltons, and can be purified by an immunoaffinity chromatography process. The antigen has further utility in diagnostic tests for anaplasmosis. It can be synthesized by polypeptide procedures or by genetic engineering. DNA and amino acid sequences have been developed for the antigen according to this invention. The antigen is useful as a vaccine component for protecting mammals against infection by Anaplasma marginale and may be useful for rickettsial organisms other than Anaplasma marginale.
    Type: Grant
    Filed: April 15, 1994
    Date of Patent: August 27, 1996
    Inventors: Travis C. McGuire, Guy H. Palmer, Anthony F. Barbet, William C. Davis
  • Cloned Babesia DNA
    Patent number: 5518916
    Abstract: The subject invention concerns the identification of novel merozoite surface proteins of Babesia bovis. Also disclosed are monoclonal antibodies to these proteins as well as genes which encode for the proteins. The invention further concerns the use of the novel proteins, recombinant DNA clones, and monoclonal antibodies in the detection, treatment, and prophylaxis of babesiosis.
    Type: Grant
    Filed: November 21, 1994
    Date of Patent: May 21, 1996
    Assignee: The United States of America as represented by the Secratary of Agriculture
    Inventors: Terry F. McElwain, Travis C. McGuire, Douglas P. Jasmer, David W. Reduker, deceased, Will L. Goff, David Stiller
  • Immunization against babesiosis using purified surface antigens of Babesia bigemina and similar immunogens
    Patent number: 5422428
    Abstract: Antigenic surface proteins from the intraerythrocytic merozoite stage of Babesia bigemina have been isolated using cell fusions and monoclonal antibodies produced thereby. The gene encoding a 58 kD surface protein has been identified and the DNA sequence determined and compared with sequences of other known merozoite proteins. Immunization of mammals, such as bovines, with purified isolates induces an immunological response that is effective to reduce pathological effects of babesiosis induced by Babesia bigemina. Diagnostic kits using monoclonal antibodies and antigenic surface proteins of Babesia bigemina are also disclosed.
    Type: Grant
    Filed: December 6, 1991
    Date of Patent: June 6, 1995
    Assignee: Washington State University
    Inventors: Travis C. McGuire, Terry F. McElwain, Lance E. Perryman, William C. Davis
  • Cloning of the Babesia bovis 60 KD antigen
    Patent number: 5171685
    Abstract: The subject invention concerns the identification of novel merozoite surface proteins of Babesia bovis. Also disclosed are monoclonal antibodies to these proteins as well as genes which encode for the proteins.The invention further concerns the use of the novel proteins, recombinant DNA clones, and monoclonal antibodies in the detection, treatment, and prophylaxis of babesiosis.
    Type: Grant
    Filed: April 4, 1990
    Date of Patent: December 15, 1992
    Assignees: University of Florida, The United States of America as represented by the United States Department of Agriculture
    Inventors: Terry F. McElwain, Stephen A. Hines, Travis C. McGuire, Guy H. Palmer, Douglas P. Jasmer, David W. Reduker, Will L. Goff, Lance E. Perryman, William C. Davis
  • Diagnostic test for staphylococcal mastitis
    Patent number: 5132210
    Abstract: The present invention relates to (1) an enzyme-linked immunosorbent assay (ELISA) for detection in milk of antibodies of any isotype which are specific for Staphylococcus aureus proteins in molecular weights ranging from 14,000 to 26,000 daltons, (2) a process for production and purification of the proteins, (3) a method of performing the ELISA utilizing the proteins (4) use of the ELISA for detection of intramammary infection by S. aureus, (5) preparation of monoclonal and polyclonal antibodies against the selected fractions, (6) use of such antibodies of purification of infection specfic antigens, and (7) use of the antibodies in an ELISA for antibodies produced in an individual in response to infection by S. aureus.
    Type: Grant
    Filed: June 12, 1989
    Date of Patent: July 21, 1992
    Assignee: ProScience Corporation
    Inventors: D. Scott Adams, Travis C. McGuire, Jr.