Patents by Inventor Trent A. Poole
Trent A. Poole has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 8215300Abstract: A dry powder inhaler having improved aerodynamic properties for diluting, dispersing, and metering drug particles for increasing the efficiency of pulmonary drug delivery to a patient is described. The inhaler comprises, in general, a housing having an air intake, an air flow-control/check-valve, a mixing section and a mouthpiece. A cartridge loaded with a single dose of medicament can be installed in the mixing section.Type: GrantFiled: April 14, 2008Date of Patent: July 10, 2012Assignee: MannKind CorporationInventors: Solomon S. Steiner, Trent A. Poole, Per B. Fog, Roderike Pohl, Michael Crick, Robert Feldstein
-
Patent number: 8166970Abstract: An inhaler is instantly activated upon its removal from a cover or cover unit, and by rotating a cartridge component of the inhaler with respect to a mouthpiece portion, so as to create a flow pathway for ambient air and particles. The cartridge component includes a chamber, whose contents typically include dry powders or the like. Upon creation of the flow pathway, the contents of the chamber are instantly accessible for immediate inhalation by a user through the mouthpiece portion.Type: GrantFiled: October 5, 2006Date of Patent: May 1, 2012Assignee: MannKind CorporationInventors: Trent Poole, Solomon S. Steiner
-
Patent number: 8156936Abstract: Described are dry powder inhalers comprising an intake section, a mixing section and a mouthpiece. The mixing section can accommodate a capsule having a top keying portion and containing a dry powder medicament. The top keying portion of the capsules may fit within complementary keying structures in inhaler mixing sections.Type: GrantFiled: November 2, 2007Date of Patent: April 17, 2012Assignee: MannKind CorporationInventors: Solomon S. Steiner, Per B. Fog, Trent Poole, Robert Feldstein
-
Patent number: 8146588Abstract: Described are dry powder inhalers composing an intake section, a mixing section and a mouthpiece. The mixing section can accommodate a capsule having a top keying portion and containing a dry powder medicament. The top keying portion of the capsules may fit within complementary keying structures in inhaler mixing sections.Type: GrantFiled: December 3, 2007Date of Patent: April 3, 2012Assignee: MannKind CorporationInventors: Solomon S. Steiner, Robert Feldstein, Per B. Fog, Trent A. Poole
-
Patent number: 8025082Abstract: Powder dispensing and sensing apparatus and methods are provided. The powder dispensing and sensing apparatus includes a tray support structure to receive a cartridge tray holding cartridges, a powder dispenser assembly including powder dispenser modules to dispense powder into respective cartridges of a batch of cartridges in the cartridge tray, a powder transport system to deliver powder to the powder dispenser modules, a sensor module including sensor cells to sense respective fill states, such as the weights, of each of the cartridges in the batch of cartridges, and a control system to control the powder dispenser modules in response to the respective sensed fill states of each of the cartridges of the batch of cartridges.Type: GrantFiled: October 7, 2010Date of Patent: September 27, 2011Assignee: MannKind CorporationInventors: Trent A. Poole, David F. Bonneau, Per B. Fog
-
Publication number: 20110197990Abstract: Powder dispensing and sensing apparatus and methods are provided. The powder dispensing and sensing apparatus includes a tray support structure to receive a cartridge tray holding cartridges, a powder dispenser assembly including powder dispenser modules to dispense powder into respective cartridges of a batch of cartridges in the cartridge tray, a powder transport system to deliver powder to the powder dispenser modules, a sensor module including sensor cells to sense respective fill states, such as the weights, of each of the cartridges in the batch of cartridges, and a control system to control the powder dispenser modules in response to the respective sensed fill states of each of the cartridges of the batch of cartridges.Type: ApplicationFiled: April 26, 2011Publication date: August 18, 2011Applicant: MannKind CorporationInventors: Trent A. Poole, David F. Bonneau, Per B. Fog
-
Publication number: 20110173933Abstract: A powder dispenser module (54) includes a housing (150) that defines a conduit connecting a powder inlet and a powder outlet, a feed wand (160) to move powder through the conduit from the powder inlet to the powder outlet, the feed wand (200) including a lower feed element (230) coupled to a first drive shaft and an upper feed element (220) coupled to a second drive shaft, a first actuator coupled to the first drive shaft to rotate the lower feed element (230), and a second actuator coupled to the second drive shaft to rotate the upper feed element (220). In other embodiments, the feed wand (200) includes a shaft having a fluidizing element and an actuator produces oscillatory movement of the feed wand during dispensing of powder. Dispenser module arrays include one or a few rows of dispenser modules.Type: ApplicationFiled: August 5, 2009Publication date: July 21, 2011Applicant: MannKind CorporationInventors: Rajesh Maheshwari, Rolf Scharger, Trent A. Poole, Per B. Fog
-
Patent number: 7958916Abstract: Powder dispensing and sensing apparatus and methods are provided. The powder dispensing and sensing apparatus includes a tray support structure to receive a cartridge tray holding cartridges, a powder dispenser assembly including powder dispenser modules to dispense powder into respective cartridges of a batch of cartridges in the cartridge tray, a powder transport system to deliver powder to the powder dispenser modules, a sensor module including sensor cells to sense respective fill states, such as the weights, of each of the cartridges in the batch of cartridges, and a control system to control the powder dispenser modules in response to the respective sensed fill states of each of the cartridges of the batch of cartridges.Type: GrantFiled: November 20, 2006Date of Patent: June 14, 2011Assignee: MannKind CorporationInventors: Trent A. Poole, David F. Bonneau, Per B. Fog
-
Patent number: 7950423Abstract: Powder dispensing and sensing apparatus and methods are provided. The powder dispensing and sensing apparatus includes a tray support structure to receive a cartridge tray holding cartridges, a powder dispenser assembly including powder dispenser modules to dispense powder into respective cartridges of a batch of cartridges in the cartridge tray, a powder transport system to deliver powder to the powder dispenser modules, a sensor module including sensor cells to sense respective fill states, such as the weights, of each of the cartridges in the batch of cartridges, and a control system to control the powder dispenser modules in response to the respective sensed fill states of each of the cartridges of the batch of cartridges.Type: GrantFiled: November 20, 2006Date of Patent: May 31, 2011Assignee: MannKind CorporationInventors: Trent A. Poole, David F. Bonneau, Per B. Fog
-
Publication number: 20110079318Abstract: Powder dispensing and sensing apparatus and methods are provided. The powder dispensing and sensing apparatus includes a tray support structure to receive a cartridge tray holding cartridges, a powder dispenser assembly including powder dispenser modules to dispense powder into respective cartridges of a batch of cartridges in the cartridge tray, a powder transport system to deliver powder to the powder dispenser modules, a sensor module including sensor cells to sense respective fill states, such as the weights, of each of the cartridges in the batch of cartridges, and a control system to control the powder dispenser modules in response to the respective sensed fill states of each of the cartridges of the batch of cartridges.Type: ApplicationFiled: December 15, 2010Publication date: April 7, 2011Applicant: MannKind CorporationInventors: Trent A. Poole, David F. Bonneau, Per B. Fog
-
Publication number: 20110023995Abstract: Powder dispensing and sensing apparatus and methods are provided. The powder dispensing and sensing apparatus includes a tray support structure to receive a cartridge tray holding cartridges, a powder dispenser assembly including powder dispenser modules to dispense powder into respective cartridges of a batch of cartridges in the cartridge tray, a powder transport system to deliver powder to the powder dispenser modules, a sensor module including sensor cells to sense respective fill states, such as the weights, of each of the cartridges in the batch of cartridges, and a control system to control the powder dispenser modules in response to the respective sensed fill states of each of the cartridges of the batch of cartridges.Type: ApplicationFiled: October 7, 2010Publication date: February 3, 2011Applicant: MannKind CorporationInventors: Trent A. Poole, David F. Bonneau, Per B. Fog
-
Patent number: 7836922Abstract: Powder dispensing and sensing apparatus and methods are provided. The powder dispensing and sensing apparatus includes a tray support structure to receive a cartridge tray holding cartridges, a powder dispenser assembly including powder dispenser modules to dispense powder into respective cartridges of a batch of cartridges in the cartridge tray, a powder transport system to deliver powder to the powder dispenser modules, a sensor module including sensor cells to sense respective fill states, such as the weights, of each of the cartridges in the batch of cartridges, and a control system to control the powder dispenser modules in response to the respective sensed fill states of each of the cartridges of the batch of cartridges.Type: GrantFiled: November 20, 2006Date of Patent: November 23, 2010Assignee: MannKind CorporationInventors: Trent A. Poole, David F. Bonneau, Per B. Fog
-
Patent number: 7658721Abstract: A drug delivery device that aerosolizes a dry powder formulation so that it forms a fine coating in the oral cavity and, more specifically in the sublingual region of the oral cavity is described herein. In the preferred embodiment, the device contains five main parts: (i) a compressed gas canister, (ii) a dispenser body (also referred to herein as the main housing ), (iii) a means for storing one or more doses of a drug formulation, (iv) a means for releasing a dose of the drug formulation such as a gas canister or spring piston and (v) a mouthpiece. Preferred configurations include circular, tubular, and rectangular. The means for storing the drug formulation may be configured to separately store one or more materials. In one embodiment, the means for storing the active agent is in the form of one or more drug discs, where the drug discs contain a plurality of blister packs, each storing one dose of the drug formulation.Type: GrantFiled: January 18, 2005Date of Patent: February 9, 2010Assignee: Biodel Inc.Inventors: Solomon S. Steiner, Craig Brown, Roderike Pohl, Trent Poole, Erik Steiner
-
Patent number: 7464706Abstract: A dry powder inhaler having improved aerodynamic properties for diluting, dispersing, and metering drug particles for increasing the efficiency of pulmonary drug delivery to a patient is described. The inhaler comprises, in general, a housing having an air intake, an air flow-control/check-valve, a mixing section and a mouthpiece. A cartridge loaded with a single dose of medicament can be installed in the mixing section.Type: GrantFiled: September 4, 2003Date of Patent: December 16, 2008Assignee: MannKind CorporationInventors: Solomon S. Steiner, Trent A. Poole, Per B. Fog, Roderike Pohl, Michael Crick, Robert Feldstein
-
Publication number: 20080190425Abstract: A dry powder inhaler having improved aerodynamic properties for diluting, dispersing, and metering drug particles for increasing the efficiency of pulmonary drug delivery to a patient is described. The inhaler comprises, in general, a housing having an air intake, an air flow-control/check-valve, a mixing section and a mouthpiece. A cartridge loaded with a single dose of medicament can be installed in the mixing section.Type: ApplicationFiled: April 14, 2008Publication date: August 14, 2008Inventors: Solomon S. Steiner, Trent A. Poole, Per B. Fog, Roderike Pohl, Michael Crick, Robert Feldstein
-
Publication number: 20080127970Abstract: Described is a dry powder inhaler comprising an intake section; a mixing section, and a mouthpiece. The mouthpiece is connected by a swivel joint to the mixing section, and may swivel back onto the intake section and be enclosed by a cover. The intake chamber comprises a special piston with a tapered piston rod and spring, and one or more bleed-through orifices to modulate the flow of air through the device. The intake chamber further optionally comprises a feedback module to generate a tone indicating to the user when the proper rate of airflow has been achieved. The mixing section holds a capsule with holes containing a dry powder medicament, and the cover only can open when the mouthpiece is at a certain angle to the intake section. The mixing section further opens and closes the capsule when the intake section is at a certain angle to the mouthpiece. The mixing section is a Venturi chamber configured by protrusions or spirals to impart a cyclonic flow to air passing through the mixing chamber.Type: ApplicationFiled: December 3, 2007Publication date: June 5, 2008Applicant: MANNKIND CORPORATIONInventors: Solomon S. Steiner, Robert Feldstein, Per B. Fog, Trent Poole
-
Publication number: 20080053437Abstract: Described is a dry powder inhaler comprising an intake section; a mixing section, and a mouthpiece. The mouthpiece is connected by a swivel joint to the mixing section, and may swivel back onto the intake section and be enclosed by a cover. The intake chamber comprises a special piston with a tapered piston rod and spring, and one or more bleed-through orifices to modulate the flow of air through the device. The intake chamber further optionally comprises a feedback module to generate a tone indicating to the user when the proper rate of airflow has been achieved. The mixing section holds a capsule with holes containing a dry powder medicament, and the cover only can open when the mouthpiece is at a certain angle to the intake section. The mixing section further opens and closes the capsule when the intake section is at a certain angle to the mouthpiece. The mixing section is a Venturi chamber configured by protrusions or spirals to impart a cyclonic flow to air passing through the mixing chamber.Type: ApplicationFiled: November 2, 2007Publication date: March 6, 2008Applicant: MANNKIND CORPORATIONInventors: Solomon Steiner, Robert Feldstein, Per Fog, Trent Poole
-
Publication number: 20080047550Abstract: A drug delivery device that aerosolizes a dry powder formulation so that it forms a fine coating in the oral cavity and, more specifically in the sublingual region of the oral cavity is described herein. In the preferred embodiment, the device contains five main parts: (i) a compressed gas canister, (ii) a dispenser body (also referred to herein as the main housing ), (iii) a means for storing one or more doses of a drug formulation, (iv) a means for releasing a dose of the drug formulation such as a gas canister or spring piston and (v) a mouthpiece. Preferred configurations include circular, tubular, and rectangular. The means for storing the drug formulation may be configured to separately store one or more materials. In one embodiment, the means for storing the active agent is in the form of one or more drug discs, where the drug discs contain a plurality of blister packs, each storing one dose of the drug formulation.Type: ApplicationFiled: January 18, 2005Publication date: February 28, 2008Applicant: Biodel, Inc.Inventors: Solomon Steiner, Craig Brown, Roderike Pohl, Trent Poole, Erik Steiner
-
Publication number: 20080041372Abstract: An inhaler is instantly activated upon its removal from a cover or cover unit, and by rotating a cartridge component of the inhaler with respect to a mouthpiece portion, so as to create a flow pathway for ambient air and particles. The cartridge component includes a chamber, whose contents typically include dry powders or the like. Upon creation of the flow pathway, the contents of the chamber are instantly accessible for immediate inhalation by a user through the mouthpiece portion.Type: ApplicationFiled: October 5, 2006Publication date: February 21, 2008Inventors: Trent Poole, Solomon Steiner
-
Patent number: 7305986Abstract: Described are capsules to contain a drug for use in an inhaler. The capsules may be two-part capsules where each half has apertures which may correspond to apertures in the other half. The first half fits snugly within the second half and the two halves may be rotated around their longitudinal axes with respect to each other to produce unlocked and locked positions. In the unlocked position, at least one aperture in the first half aligns with at least one aperture in the second half, which permits introduction of a medicament. In the locked position, at least two apertures in the first half align with at least two apertures in the second half, allowing air to pass through the capsule, releasing the medicament contained therein. Each capsule may have a unique key on each half that only fits with a particular inhaler or identifies the medicament contained therein.Type: GrantFiled: July 21, 2000Date of Patent: December 11, 2007Assignee: MannKind CorporationInventors: Solomon S. Steiner, Robert Feldstein, Per B. Fog, Trent Poole