Patents by Inventor Trevor Clive Dale

Trevor Clive Dale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR CULTURING ORGANOIDS
    Publication number: 20220333064
    Abstract: The present invention provides a method for culturing organoids, the method comprising: a) disassociating unprocessed organoids to produce a cell suspension; b) sieving the cell suspension through a cell strainer to retain a sieved cell suspension containing cells of about 10 ?m to about 1 mm in diameter; and c) seeding cells of the sieved cell suspension into a bioreactor in a cell culture medium comprising an extracellular support matrix.
    Type: Application
    Filed: July 6, 2022
    Publication date: October 20, 2022
    Inventors: Marianne J. ELLIS, Julian CHAUDHURI, Trevor Clive DALE
  • Methods for culturing organoids
    Patent number: 11401501
    Abstract: The present invention provides a method for culturing organoids, the method comprising: a) disassociating unprocessed organoids to produce a cell suspension; b) sieving the cell suspension through a cell strainer to retain a sieved cell suspension containing cells of about 10 ?m to about 1 mm in diameter; and c) seeding cells of the sieved cell suspension into a bioreactor in a cell culture medium comprising an extracellular support matrix.
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: August 2, 2022
    Assignee: CELLESCE LIMITED
    Inventors: Marianne J. Ellis, Julian Chaudhuri, Trevor Clive Dale
  • METHODS FOR CULTURING ORGANOIDS
    Publication number: 20190249137
    Abstract: The present invention provides a method for culturing organoids, the method comprising: a) disassociating unprocessed organoids to produce a cell suspension; b) sieving the cell suspension through a cell strainer to retain a sieved cell suspension containing cells of about 10 ?m to about 1 mm in diameter; and c) seeding cells of the sieved cell suspension into a bioreactor in a cell culture medium comprising an extracellular support matrix.
    Type: Application
    Filed: July 11, 2017
    Publication date: August 15, 2019
    Inventors: Marianne J. ELLIS, Julian CHAUDHURI, Trevor Clive DALE
  • METHOD OF MEASURING THE AFFINITY OF BIOMOLECULES
    Publication number: 20170370927
    Abstract: The invention provides a method of measuring the affinity of first and second biomolecules in which a first biomolecule is tethered by a first tether portion having a first tether portion length and a second biomolecule is tethered by a second tether portion having a second tether portion length, the method comprising determining binding of adjacent first and second biomolecules to each other, varying at least one of the first and second tether lengths and determining binding of the first and second biomolecules. The invention also provides apparatus suitable for use in the method of the invention.
    Type: Application
    Filed: July 7, 2017
    Publication date: December 28, 2017
    Inventors: Trevor Clive DALE, Adrian John HARWOOD, Paola BORRI
  • METHOD
    Publication number: 20140323328
    Abstract: The invention provides a method of measuring the affinity of first and second biomolecules in which a first biomolecule is tethered by a first tether portion having a first tether portion length and a second biomolecule is tethered by a second tether portion having a second tether portion length, the method comprising determining binding of adjacent first and second biomolecules to each other, varying at least one of the first and second tether lengths and determining binding of the first and second biomolecules. The invention also provides apparatus suitable for use in the method of the invention.
    Type: Application
    Filed: March 21, 2014
    Publication date: October 30, 2014
    Inventors: Trevor Clive DALE, Adrian John HARWOOD, Paola BORRI
  • Method of measuring the affinity of biomolecules
    Patent number: 8778697
    Abstract: The invention provides a method of measuring the affinity of first and second biomolecules in which a first biomolecule is tethered by a first tether portion having a first tether portion length and a second biomolecule is tethered by a second tether portion having a second tether portion length, the method comprising determining binding of adjacent first and second biomolecules to each other, varying at least one of the first and second tether lengths and determining binding of the first and second biomolecules. The invention also provides apparatus suitable for use in the method of the invention.
    Type: Grant
    Filed: November 10, 2006
    Date of Patent: July 15, 2014
    Assignee: Nanotether Discovery Science Limited
    Inventors: Trevor Clive Dale, Adrian John Harwood, Paola Borri
  • METHOD
    Publication number: 20090023227
    Abstract: The invention provides a method of measuring the affinity of first and second biomolecules in which a first biomolecule is tethered by a first tether portion having a first tether portion length and a second biomolecule is tethered by a second tether portion having a second tether portion length, the method comprising determining binding of adjacent first and second biomolecules to each other, varying at least one of the first and second tether lengths and determining binding of the first and second biomolecules. The invention also provides apparatus suitable for use in the method of the invention.
    Type: Application
    Filed: November 10, 2006
    Publication date: January 22, 2009
    Inventors: Trevor Clive Dale, Adrian John Hardwood, Paola Borri