Patents by Inventor Troy Holland
Troy Holland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230138968Abstract: The present disclosure provides metalloporphyrin and metallochlorin compounds (e.g., compounds of Formula (II) and (III)), which are useful in the preparation of optical devices (e.g., contact lenses, intraocular lenses, implantable contact lenses) that protect retinal pigment epithelium by the selective blocking of blue light. Also provided are precursor porphyrin and chlorin compounds (e.g., compounds of Formula (I)), and compositions and optical devices incorporating the compounds of the disclosure. Also provided are methods of selecting appropriate metalloporphyrin and metallochlorin compounds for incorporation into optical devices wherein the devices mitigate damage to retinal epithelial cells while balancing changes to luminous transmission, discomfort glare, color distortion, and disruption of circadian rhythms.Type: ApplicationFiled: November 1, 2022Publication date: May 4, 2023Applicant: High Performance Optics, Inc.Inventors: Mark Acerson, David Owen Baumann, Dustin Cefalo, Frank Chang, Peter Haaland, Troy Holland, Andrew Ishak, Raja Gabadage Waruna E. Jinadasa, Mark L. Nelson, Larry Rodriguez, Adam Sniady, Houliang Tang, Jiangxing Zhang
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Publication number: 20220354720Abstract: Safety guards for use with a bed rail are disclosed. A safety guard may be coupled to a mattress without being coupled to a bed rail, or a safety guard may be coupled to a mattress and to a bed rail. The safety guards may reduce a risk of entrapment between the mattress and the bed rail by distributing weight on the mattress across a wide surface area. A safety guard may be disposed underneath a sheet on the mattress. The safety guard may remain coupled to the mattress without inhibiting changing of sheets on the mattress.Type: ApplicationFiled: April 22, 2022Publication date: November 10, 2022Inventors: F. Troy Miller, Troy Holland, Kip D. Alder, Adam Scott, Benjamin Miller, Brandon Birch
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Patent number: 8221735Abstract: Embolic compositions comprising macromers having a backbone comprising a polymeric backbone comprising units with a 1,2-diol or 1,3-diol structure, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups and, optionally, other modifiers. When crosslinked, the macromers form hydrogels having many properties advantageous for use as embolic agents to block and fill lumens and spaces. The embolic compositions can be used as liquid embolic agents and crosslinked in situ or as preformed embolic articles, such as microspheres.Type: GrantFiled: April 23, 2009Date of Patent: July 17, 2012Assignee: BioCure, Inc.Inventors: Dennis W. Goupil, Hassan Chaouk, Troy Holland, Bruktawit T. Asfaw, Stephen D. Goodrich, Lucas Latini
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Publication number: 20090209658Abstract: Embolic compositions comprising macromers having a backbone comprising a polymeric backbone comprising units with a 1,2-diol or 1,3-diol structure, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups and, optionally, other modifiers. When crosslinked, the macromers form hydrogels having many properties advantageous for use as embolic agents to block and fill lumens and spaces. The embolic compositions can be used as liquid embolic agents and crosslinked in situ or as preformed embolic articles, such as microspheres.Type: ApplicationFiled: April 23, 2009Publication date: August 20, 2009Inventors: Dennis W. Goupil, Hassan Chaouk, Troy Holland, Bruktawit T. Asfaw, Stephen D. Goodrich, Lucas Latini
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Publication number: 20070113933Abstract: Metallic glasses of superior mechanical and magnetic properties are manufactured by annealing the glasses under the influence of an electric current to convert the glass to a composite that includes crystallites, preferably nanocrystallites, dispersed through an amorphous matrix.Type: ApplicationFiled: June 22, 2006Publication date: May 24, 2007Applicant: The Regents of the University of CaliforniaInventors: Zuhair Munir, Troy Holland, Jorg Loffler
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Publication number: 20060241242Abstract: The invention provides a continuous-flow process for producing a polymeric material. The process of the invention comprises the steps of: introducing at least two solutions, each comprising one or more reactants, into a microreactor to mix the two solutions to form a reacting solution, wherein the one or more reactants are selected from the group consisting of a monomer, an initiator, a coupling agent, a prepolymer, a macromer, and mixtures thereof; feeding continuously the reacting solution into a flow-through polymerization reactor in a coil form, wherein the flow-through polymerization reactor is capable of providing a residence time sufficient for (co)polymerizing the reactants to form a polymer with a desired polydispersity, wherein the flow-through polymerization reactor is immersed in an ultrasonic bath to minimize or substantially eliminate unwanted high-molecular-weight fractions of the polymer.Type: ApplicationFiled: March 1, 2006Publication date: October 26, 2006Inventors: Brian Devlin, Troy Holland, Dawn Smith, Alexander Azzawi
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Patent number: 7070809Abstract: Hydrogel biomedical articles formed from macromers having a polymeric backbone comprising 1,2-diol and/or 1,3-diol units, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups and, optionally, other modifiers.Type: GrantFiled: March 13, 2001Date of Patent: July 4, 2006Assignee: BioCure, Inc.Inventors: Dennis W. Goupil, Hassan Chaouk, Troy Holland, Bruktawit T. Asfaw, Stephen D. Goodrich, Lucas Latini
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Publication number: 20060137778Abstract: Metallic glasses of superior mechanical and magnetic properties are manufactured by annealing the glasses under the influence of an electric current to convert the glass to a composite that includes crystallites, preferably nanocrystallites, dispersed through an amorphous matrix.Type: ApplicationFiled: June 17, 2003Publication date: June 29, 2006Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Zuhair Munir, Troy Holland, Jorg Loffler
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Publication number: 20050129656Abstract: Compositions comprising macromers having a backbone comprising units having a 1,2-diol and/or 1,3-diol structure for tissue bulking and coating. Such polymers include poly(vinyl alcohol) (PVA) and hydrolyzed copolymers of vinyl acetate, for example, copolymers with vinyl chloride, N-vinylpyrrolidone, etc. The backbone polymer contains pendant chains bearing crosslinkable groups and, optionally, other modifiers. When crosslinked, the macromers form hydrogels having many properties advantageous for use as agents to hulk and coat tissues.Type: ApplicationFiled: January 13, 2005Publication date: June 16, 2005Applicant: BioCure, Inc.Inventors: Dennis Goupil, Hassan Chaouk, Troy Holland, Bruktawit Asfaw, Stepehen Goodrich, Lucas Latini
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Patent number: 6710126Abstract: Biodegradable biocompatible hydrogels based on poly(vinyl alcohol) and methods for their preparation. The methods for preparation of the hydrogels involve the use of prepolymers. The prepolymers have a PVA backbone and pendant chains that include a polymerizable group. In one embodiment, the pendant chains also include a biodegradable region. In another embodiment, biodegradable regions are incorporated into the hydrogel during its formation.Type: GrantFiled: November 15, 2000Date of Patent: March 23, 2004Assignee: Bio Cure, Inc.Inventors: Thomas Hirt, Troy Holland, Vimala Francis, Hassan Chaouk
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Patent number: 6676971Abstract: Embolic compositions comprising macromers having a backbone comprising a polymeric backbone comprising units with a 1,2-diol or 1,3-diol structure, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups and, optionally, other modifiers. When crosslinked, the macromers form hydrogels having many properties advantageous for use as embolic agents to block and fill lumens and spaces. The embolic compositions can be used as liquid embolic agents and crosslinked in situ or as preformed embolic articles, such as microspheres.Type: GrantFiled: March 13, 2001Date of Patent: January 13, 2004Assignee: BioCure, Inc.Inventors: Dennis W. Goupil, Hassan Chaouk, Troy Holland, Bruktawit T. Asfaw, Stephen D. Goodrich, Lucas Latini
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Publication number: 20030223956Abstract: Embolic compositions comprising macromers having a backbone comprising a polymeric backbone comprising units with a 1,2-diol or 1,3-diol structure, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups and, optionally, other modifiers. When crosslinked, the macromers form hydrogels having many properties advantageous for use as embolic agents to block and fill lumens and spaces. The embolic compositions can be used as liquid embolic agents and crosslinked in situ or as preformed embolic articles, such as microspheres.Type: ApplicationFiled: June 19, 2003Publication date: December 4, 2003Inventors: Dennis W. Goupil, Hassan Chaouk, Troy Holland, Bruktawit T. Asfaw, Stephen D. Goodrich, Lucas Latini
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Patent number: 6652883Abstract: Compositions comprising macromers having a backbone comprising units having a 1,2-diol and/or 1,3-diol structure for tissue bulking and coating. Such polymers include poly(vinyl alcohol) (PVA) and hydrolyzed copolymers of vinyl acetate, for example, copolymers with vinyl chloride, N-vinylpyrrolidone, etc. The backbone polymer contains pendant chains bearing crosslinkable groups and, optionally, other modifiers. When crosslinked, the macromers form hydrogels having many properties advantageous for use as agents to bulk and coat tissues.Type: GrantFiled: March 13, 2001Date of Patent: November 25, 2003Assignee: BioCure, Inc.Inventors: Dennis W. Goupil, Hassan Chaouk, Troy Holland, Bruktawit T. Asfaw, Stephen D. Goodrich, Lucas Latini
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Publication number: 20030211073Abstract: Compositions comprising macromers having a backbone comprising units having a 1,2-diol and/or 1,3-diol structure for tissue bulking and coating. Such polymers include poly(vinyl alcohol) (PVA) and hydrolyzed copolymers of vinyl acetate, for example, copolymers with vinyl chloride, N-vinylpyrrolidone, etc. The backbone polymer contains pendant chains bearing crosslinkable groups and, optionally, other modifiers. When crosslinked, the macromers form hydrogels having many properties advantageous for use as agents to bulk and coat tissue.Type: ApplicationFiled: June 19, 2003Publication date: November 13, 2003Inventors: Dennis W. Goupil, Hassan Chaouk, Troy Holland, Bruktawit T. Asfaw, Stephen D. Goodrich, Lucas Latini
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Publication number: 20020122771Abstract: A wound dressing is provided that is formed in situ on the wound by spray application of a composition including a composition that gels in situ to form a hydrogel. The composition preferably includes macromers having water soluble regions and crosslinkable regions. Compositions for making a hydrogel wound dressing are also provided.Type: ApplicationFiled: September 21, 2001Publication date: September 5, 2002Inventors: Troy Holland, Hassan Chaouk, Bruktawit Asfaw, Stephen Goodrich, Adrian Hunter, Vimala Francis
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Publication number: 20010056301Abstract: Hydrogel biomedical articles formed from macromers having a polymeric backbone comprising 1,2-diol and/or 1,3-diol units, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups and, optionally, other modifiers.Type: ApplicationFiled: March 13, 2001Publication date: December 27, 2001Inventors: Dennis W. Goupil, Hassan Chaouk, Troy Holland, Bruktawit T. Asfaw, Stephen D. Goodrich, Lucas Latini
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Publication number: 20010051670Abstract: Compositions comprising macromers having a backbone comprising units having a 1,2-diol and/or 1,3-diol structure for tissue bulking and coating. Such polymers include poly(vinyl alcohol) (PVA) and hydrolyzed copolymers of vinyl acetate, for example, copolymers with vinyl chloride, N-vinylpyrrolidone, etc. The backbone polymer contains pendant chains bearing crosslinkable groups and, optionally, other modifiers. When crosslinked, the macromers form hydrogels having many properties advantageous for use as agents to bulk and coat tissues.Type: ApplicationFiled: March 13, 2001Publication date: December 13, 2001Inventors: Dennis W. Goupil, Hassan Chaouk, Troy Holland, Bruktawit T. Asfaw, Stephen D. Goodrich, Lucas Latini
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Patent number: RE47121Abstract: Embolic compositions comprising macromers having a backbone comprising a polymeric backbone comprising units with a 1,2-diol or 1,3-diol structure, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups and, optionally, other modifiers. When crosslinked, the macromers form hydrogels having many properties advantageous for use as embolic agents to block and fill lumens and spaces. The embolic compositions can be used as liquid embolic agents and crosslinked in situ or as preformed embolic articles, such as microspheres.Type: GrantFiled: July 17, 2014Date of Patent: November 13, 2018Assignee: BioCure, Inc.Inventors: Dennis W. Goupil, Hassan Chaouk, Troy Holland, Bruktawit T. Asfaw, Stephen D. Goodrich, Lucas Latini
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Patent number: RE47873Abstract: Embolic compositions comprising macromers having a backbone comprising a polymeric backbone comprising units with a 1,2-diol or 1,3-diol structure, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups and, optionally, other modifiers. When crosslinked, the macromers form hydrogels having many properties advantageous for use as embolic agents to block and fill lumens and spaces. The embolic compositions can be used as liquid embolic agents and crosslinked in situ or as preformed embolic articles, such as microspheres.Type: GrantFiled: March 16, 2015Date of Patent: February 25, 2020Assignee: BIOCOMPATIBLES UK LIMITEDInventors: Dennis W. Goupil, Hassan Chaouk, Troy Holland, Bruktawit T. Asfaw, Stephen D. Goodrich, Lucas Latini
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Patent number: RE48302Abstract: Embolic compositions comprising macromers having a backbone comprising a polymeric backbone comprising units with a 1,2-diol or 1,3-diol structure, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups and, optionally, other modifiers. When crosslinked, the macromers form hydrogels having many properties advantageous for use as embolic agents to block and fill lumens and spaces. The embolic compositions can be used as liquid embolic agents and crosslinked in situ or as preformed embolic articles, such as microspheres.Type: GrantFiled: July 26, 2018Date of Patent: November 10, 2020Assignee: BioCure, Inc.Inventors: Dennis Goupil, Hassan Chaouk, Troy Holland, Bruktawit Asfaw, Stephen D. Goodrich, Lucas Latini