Patents by Inventor Trudy Grossman

Trudy Grossman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIODEFENSE AGENTS
    Publication number: 20210253577
    Abstract: The present disclosure relates to methods of treating, preventing, reducing the risk of, or delaying the onset of microbial infections in humans and animals that are caused by or involves one or more microorganisms which are capable of being used as biological weapons, the method including administering a pyrrolocytosine compound or a tautomer thereof or a pharmaceutically acceptable salt of the compound or tautomer.
    Type: Application
    Filed: June 6, 2019
    Publication date: August 19, 2021
    Inventors: Ashoke Bhattacharjee, Erin M. Duffy, Trudy Grossman, Joseph A. Ippolito, Zoltan F. Kanyo
  • Polycyclic Tetracycline Compounds
    Publication number: 20170107179
    Abstract: The present invention is directed to a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (I) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (I) and its therapeutic use.
    Type: Application
    Filed: May 25, 2016
    Publication date: April 20, 2017
    Inventors: Xiao-Yi Xiao, Roger B. Clark, Diana Katharine Hunt, Magnus P. Ronn, Louis Plamondon, Minsheng He, Joyce A. Sutcliffe, Trudy Grossman
  • Polycyclic tetracycline compounds
    Patent number: 9371283
    Abstract: The present invention is directed to a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (I) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (I) and its therapeutic use.
    Type: Grant
    Filed: March 30, 2011
    Date of Patent: June 21, 2016
    Assignee: Tetraphase Pharmaceuticals, Inc.
    Inventors: Xiao-Yi Xiao, Roger Clark, Diana Hunt, Magnus Rönn, Louis Plamondon, Minsheng He, Joyce Sutcliffe, Trudy Grossman
  • Inhibitors of bacterial IMPDH
    Patent number: 8202889
    Abstract: The present invention relates to methods of inhibiting bacterial IMPDH comprising administering compounds of formula I: or pharmaceutically acceptable salts thereof. The present invention also relates to pharmaceutically acceptable compositions comprising said compounds. These compounds, and compositions thereof, are useful in treating bacterial infections.
    Type: Grant
    Filed: September 8, 2006
    Date of Patent: June 19, 2012
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Paul Charifson, Trudy Grossman, Emanuele Perola
  • Polycyclic Tetracycline Compounds
    Publication number: 20110269714
    Abstract: The present invention is directed to a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (I) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (I) and its therapeutic use.
    Type: Application
    Filed: March 30, 2011
    Publication date: November 3, 2011
    Applicant: Tetraphase Pharmaceuticals, Inc.
    Inventors: Xiao-Yi Xiao, Roger Clark, Diana Hunt, Magnus Rönn, Louis Plamondon, Minsheng He, Joyce Sutcliffe, Trudy Grossman
  • Inhibitors of bacterial IMPDH
    Publication number: 20070191434
    Abstract: The present invention relates to methods of inhibiting bacterial IMPDH comprising administering compounds of formula I: or pharmaceutically acceptable salts thereof. The present invention also relates to pharmaceutically acceptable compositions comprising said compounds. These compounds, and compositions thereof, are useful in treating bacterial infections.
    Type: Application
    Filed: September 8, 2006
    Publication date: August 16, 2007
    Inventors: Paul Charifson, Trudy Grossman, Emanuele Perola
  • Potentiators of antibacterial activity
    Publication number: 20050090482
    Abstract: The present invention relates to compounds that potentiate the activity of antibacterials. The present invention also relates to compositions useful in treating bacterial infection in mammals, and methods therewith. The present invention also relates to a method of inhibiting bacterial efflux of an antibiotic, thereby increasing the efficacy of the antibiotic.
    Type: Application
    Filed: July 9, 2004
    Publication date: April 28, 2005
    Inventor: Trudy Grossman
  • Vectors for improving cloning and expression in low copy number plasmids
    Patent number: 6818441
    Abstract: Improved vectors and related materials and methods are disclosed.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: November 16, 2004
    Assignees: Aventis Pharmaceuticals Inc., Ariad Pharmaceuticals Inc.
    Inventors: Trudy Grossman, Ian MacNeil, Paul R. August