Patents by Inventor Tsontcho Ianchulev

Tsontcho Ianchulev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170344714
    Abstract: The present invention includes and provides a method of delivering a medicament to an eye of a subject in need thereof a solution, the method comprising: (a) providing droplets containing the medicament with a specified average size and average initial ejecting velocity; and (b) delivering the medicament to the eye, where the droplets deliver a percentage of the ejected mass of the droplets to the eye.
    Type: Application
    Filed: March 15, 2017
    Publication date: November 30, 2017
    Inventors: Bernard L. Ballou, JR., Mark Packer, Russell John Mumper, Tsontcho Ianchulev
  • Publication number: 20170159114
    Abstract: Methods for determining whether a patient is at increased risk of developing wet AMD or whether a patient has an increased likelihood of benefiting from treatment with a high-affinity anti-VEGF antibody.
    Type: Application
    Filed: July 20, 2016
    Publication date: June 8, 2017
    Applicant: GENENTECH, INC.
    Inventors: Robert Graham, Timothy W. Behrens, Tsontcho Ianchulev, Howard Shapiro
  • Patent number: 9549846
    Abstract: This disclosure relates generally to methods and devices for use in treating eye conditions with implantable drug delivery devices. One method includes introducing an implant into the suprachoroidal space, wherein the interior volume of the implant is plugged with a drug-release material comprising at least one active agent that elutes through at least one opening in the implant, wherein the drug-release material degrades from the interior volume of the implant over a period time.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: January 24, 2017
    Assignee: NOVARTIS AG
    Inventors: Luke Clauson, Thomas A. Silvestrini, Tsontcho Ianchulev, Steven John
  • Patent number: 9445890
    Abstract: Apparatus for performing intraocular implant surgery, including surgical apparatus for performing intraocular implant surgery, an autorefraction device associated with the surgical apparatus, wherein the autorefraction device is configured to perform autorefraction on the aphakic eye to provide one or more aphakic refraction measurements, and a processor connected to the autorefraction device, wherein the processor is configured to process the aphakic refraction measurements and provide the user of the apparatus with information regarding the power of the intraocular lens.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: September 20, 2016
    Assignee: WaveTec Vision Systems, Inc.
    Inventor: Tsontcho Ianchulev
  • Publication number: 20160022486
    Abstract: This disclosure relates generally to methods and devices for use in treating eye conditions with implantable drug delivery devices. One method includes introducing an implant into the suprachoroidal space, wherein the interior volume of the implant is plugged with a drug-release material comprising at least one active agent that elutes through at least one opening in the implant, wherein the drug-release material degrades from the interior volume of the implant over a period time.
    Type: Application
    Filed: July 27, 2015
    Publication date: January 28, 2016
    Inventors: Luke Clauson, Thomas A. Silvestrini, Tsontcho Ianchulev, Steven John
  • Patent number: 9210968
    Abstract: Systems, methods, and computer-readable storage media for applying an adhesive film to the sole of shoes. Application of a portion of the adhesive film can be performed by receiving a shoe on top of the adhesive film, which in turn is above a plate and compressible pins. Upon receiving the shoe, the plate is raised or lowered, and the compressible pins mark the perimeter of the sole of the shoe. The adhesive film is cut in a sole-shaped pattern due to the height differentiation, resulting in a sole-shaped portion of the adhesive film being adhered to the sole of the shoe.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: December 15, 2015
    Inventors: Tsontcho Ianchulev, Edward Y. Koo
  • Publication number: 20150328151
    Abstract: The present invention includes and provides a method of delivering a medicament to an eye of a subject in need thereof a solution, the method comprising: (a) providing droplets containing the medicament with a specified average size and average initial ejecting velocity; and (b) delivering the medicament to the eye, where the droplets deliver a percentage of the ejected mass of the droplets to the eye.
    Type: Application
    Filed: July 8, 2015
    Publication date: November 19, 2015
    Inventors: Bernard L. Ballou, JR., Mark Packer, Russell John Mumper, Tsontcho Ianchulev
  • Patent number: 9168127
    Abstract: Apparatus for performing intraocular implant surgery, including surgical apparatus for performing intraocular implant surgery, an autorefraction device associated with the surgical apparatus, wherein the autorefraction device is configured to perform autorefraction on the aphakic eye to provide one or more aphakic refraction measurements, and a processor connected to the autorefraction device, wherein the processor is configured to process the aphakic refraction measurements and provide the user of the apparatus with information regarding the power of the intraocular lens.
    Type: Grant
    Filed: October 16, 2009
    Date of Patent: October 27, 2015
    Assignee: WaveTec Vision Systems, Inc.
    Inventor: Tsontcho Ianchulev
  • Patent number: 9089392
    Abstract: This disclosure relates generally to methods and devices for use in treating eye conditions with implantable drug delivery devices. One method includes introducing an implant into the suprachoroidal space, wherein the interior volume of the implant is plugged with a drug-release material comprising at least one active agent that elutes through at least one opening in the implant, wherein the drug-release material degrades from the interior volume of the implant over a period time.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: July 28, 2015
    Assignee: Transcend Medical, Inc.
    Inventors: Luke Clauson, Thomas A. Silvestrini, Tsontcho Ianchulev, Steven John
  • Publication number: 20140323995
    Abstract: This disclosure relates generally to methods and devices for use in treating eye conditions. In some embodiments, a site-specific therapeutic agent is mixed with a releasing agent with a dual syringe apparatus in order to achieve homogeneity. Once mixed, the site-specific therapeutic agent and releasing agent can be either dispensed directly within an area of the eye or within an implant. The implant can be at least partially filled with the site-specific therapeutic agent and releasing agent either prior to or after implantation into the eye. Some ratios of site-specific therapeutic agents to releasing agents are disclosed which provide various releasing profiles of the site-specific therapeutic agent within the eye.
    Type: Application
    Filed: April 23, 2014
    Publication date: October 30, 2014
    Applicant: TRANSCEND MEDICAL, INC.
    Inventors: Luke Clauson, Tsontcho Ianchulev, Nathan White, Richard S. Lilly, Matthew Newell, Michael Schaller
  • Publication number: 20140259459
    Abstract: Systems, methods, and computer-readable storage media for applying an adhesive film to the sole of shoes. Application of a portion of the adhesive film can be performed by receiving a shoe on top of the adhesive film, which in turn is above a plate and compressible pins. Upon receiving the shoe, the plate is raised or lowered, and the compressible pins mark the perimeter of the sole of the shoe. The adhesive film is cut in a sole-shaped pattern due to the height differentiation, resulting in a sole-shaped portion of the adhesive film being adhered to the sole of the shoe.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Inventors: Tsontcho IANCHULEV, Edward Y. KOO
  • Publication number: 20140249624
    Abstract: Apparatus for performing intraocular implant surgery, including surgical apparatus for performing intraocular implant surgery, an autorefraction device associated with the surgical apparatus, wherein the autorefraction device is configured to perform autorefraction on the aphakic eye to provide one or more aphakic refraction measurements, and a processor connected to the autorefraction device, wherein the processor is configured to process the aphakic refraction measurements and provide the user of the apparatus with information regarding the power of the intraocular lens.
    Type: Application
    Filed: December 5, 2013
    Publication date: September 4, 2014
    Applicant: WaveTec Vision Systems, Inc.
    Inventor: Tsontcho Ianchulev
  • Publication number: 20140171885
    Abstract: This disclosure relates generally to methods and devices for use in treating eye conditions with implantable drug delivery devices. One method includes introducing an implant into the suprachoroidal space, wherein the interior volume of the implant is plugged with a drug-release material comprising at least one active agent that elutes through at least one opening in the implant, wherein the drug-release material degrades from the interior volume of the implant over a period time.
    Type: Application
    Filed: August 23, 2013
    Publication date: June 19, 2014
    Applicant: Transcend Medical, Inc.
    Inventors: Luke Clauson, Thomas A. Silvestrini, Tsontcho Ianchulev, Steven John
  • Patent number: 8632185
    Abstract: Apparatus for performing intraocular implant surgery, including surgical apparatus for performing intraocular implant surgery, an autorefraction device associated with the surgical apparatus, wherein the autorefraction device is configured to perform autorefraction on the aphakic eye to provide one or more aphakic refraction measurements, and a processor connected to the autorefraction device, wherein the processor is configured to process the aphakic refraction measurements and provide the user of the apparatus with information regarding the power of the intraocular lens.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: January 21, 2014
    Assignee: WaveTec Vision Systems, Inc.
    Inventor: Tsontcho Ianchulev
  • Publication number: 20130281817
    Abstract: A direct visualization (DV) system and methods for measuring one or more anatomical features of the eye, including a depth of the iridocorneal angle of the eye. The DV system can include a wire extending distally from a handle with the wire having one or more indicators for measuring anatomical features of the eye. The DV system can be deployed into the eye and used with minimal trauma to ocular tissues. Furthermore, the DV system can be used independently or alongside other ocular instruments, such as instruments having indicators corresponding to the DV system for correctly implanting ocular implants without the use of a gonio lens.
    Type: Application
    Filed: April 18, 2013
    Publication date: October 24, 2013
    Applicant: TRANSCEND MEDICAL, INC.
    Inventors: Michael Schaller, Tsontcho Ianchulev, Richard S. Lilly, Luke Clauson, David Lari
  • Patent number: 8529492
    Abstract: This disclosure relates generally to methods and devices for use in treating eye conditions with implantable drug delivery devices. One method includes introducing an implant into the suprachoroidal space, wherein the interior volume of the implant is plugged with a drug-release material comprising at least one active agent that elutes through at least one opening in the implant, wherein the drug-release material degrades from the interior volume of the implant over a period time.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: September 10, 2013
    Assignee: Trascend Medical, Inc.
    Inventors: Luke Clauson, Thomas A. Silvestrini, Tsontcho Ianchulev, Steven John
  • Publication number: 20130131687
    Abstract: Apparatus for performing intraocular implant surgery, including surgical apparatus for performing intraocular implant surgery, an autorefraction device associated with the surgical apparatus, wherein the autorefraction device is configured to perform autorefraction on the aphakic eye to provide one or more aphakic refraction measurements, and a processor connected to the autorefraction device, wherein the processor is configured to process the aphakic refraction measurements and provide the user of the apparatus with information regarding the power of the intraocular lens.
    Type: Application
    Filed: September 14, 2012
    Publication date: May 23, 2013
    Applicant: WAVETEC VISION SYSTEMS, INC.
    Inventor: Tsontcho Ianchulev
  • Patent number: 8313196
    Abstract: Apparatus for performing intraocular implant surgery, including surgical apparatus for performing intraocular implant surgery, an autorefraction device associated with the surgical apparatus, wherein the autorefraction device is configured to perform autorefraction on the aphakic eye to provide one or more aphakic refraction measurements, and a processor connected to the autorefraction device, wherein the processor is configured to process the aphakic refraction measurements and provide the user of the apparatus with information regarding the power of the intraocular lens.
    Type: Grant
    Filed: October 16, 2009
    Date of Patent: November 20, 2012
    Assignee: Wavetec Vision Systems, Inc.
    Inventor: Tsontcho Ianchulev
  • Publication number: 20120143152
    Abstract: A method of delivering safe, suitable, and repeatable dosages to a subject for topical, oral, nasal, or pulmonary use and a device for droplet ejection includes a fluid delivery system capable of delivering a defined volume of the fluid in the form of droplets having properties that afford adequate and repeatable high percentage deposition upon application. The method and device include a housing, a reservoir disposed within the housing for receiving a volume of fluid, an ejector mechanism configured to eject a stream of droplets having an average ejected droplet diameter greater than 15 microns, the stream of droplets having low entrained airflow such that the stream of droplets deposit on the eye of the subject during use.
    Type: Application
    Filed: July 15, 2011
    Publication date: June 7, 2012
    Applicant: Corinthian Ophthalmic, Inc.
    Inventors: Charles Eric HUNTER, Bernard L. Ballou, JR., Jurgen Klaus Vollrath, Arthur H. Tew, Joshua Richard Brown, James Thornhill Leath, Nathan R. Faulks, Bradley G. Johnson, J. Sid Clements, Phillip E. Russell, John H. Hebrank, Tsontcho Ianchulev, Mark Packer, Troy Elliott, Walter M. Fierson, Thomas J. Lindner
  • Patent number: 7988291
    Abstract: Apparatus for performing intraocular implant surgery, including surgical apparatus for performing intraocular implant surgery, an autorefraction device associated with the surgical apparatus, wherein the autorefraction device is configured to perform autorefraction on the aphakic eye to provide one or more aphakic refraction measurements, and a processor connected to the autorefraction device, wherein the processor is configured to process the aphakic refraction measurements and provide the user of the apparatus with information regarding the power of the intraocular lens.
    Type: Grant
    Filed: July 7, 2009
    Date of Patent: August 2, 2011
    Assignee: WaveTec Vision Systems, Inc.
    Inventor: Tsontcho Ianchulev