Abstract: A composition useful for separating lipoproteins, such as high density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (VLDL) and modified lipoproteins with a high degree of accuracy by ion-exchange based procedures. The composition comprises an organic particle having a hydrophilic surface onto which ion-exchange groups are introduced and which is formulated so as to provide a high enough degree of hydrophilicity to prevent irreversible absorption of lipoproteins, but which is not so high as to block the pores of the ion exchange particles and prevent adequate retention and separation of lipoproteins. A method for making a composition for separating lipoproteins comprising seed polymerization of organic particles, hydrophilic treatment of the organic particles by introducing 0.

Abstract: An ion exchanger for lipoproteins separation, which is an ion exchanger obtained by introducing an ion exchange group into surface hydrophilic-treated porous organic polymer particles (D) prepared by subjecting the surface of porous organic polymer particles (A) to hydrophilic treatment, wherein said hydrophilic treatment is carried out by allowing the porous organic polymer particles (A) to undergo addition reaction with a compound (B) having a cyclic other group or/and a hydrophilic group and a polymerizable unsaturated double bond and then to undergo copolymerization with a polymerizable vinyl monomer (C) having a cyclic ether group or/and a hydrophilic group, and wherein the ion exchange capacity is 0.15 milliequivalent or less per 1 g of dry ion exchanger, introduced amount of the compound (B) is from 0.

Abstract: A method for producing a spherical crosslinked copolymer, which comprises polymerizing a monofunctional addition-polymerizable monomer and at least 0.5% by weight of a polyfunctional addition-polymerizable monomer on the basis of the total weight of monomers by suspension polymerization in an aqueous medium in the presence of a radical polymerization initiator of the following formula (b) which has a decomposition temperature for a half-life period of 10 hours within a range of from 60.degree. to 120.degree. C. and which is capable of forming at least four radical initiating points per molecule by the decomposition:(R.sub.4 --O--O.paren close-st..sub.m R.sub.5 (b)wherein R.sub.4 is a linear or branched C.sub.1-10 alkyl group, R.sub.5 is a m-valent C.sub.4-25 hydrocarbon group, and m is an integer of at least 2, wherein the plurality of R.sub.4 per molecule may be the same or different.

Abstract: An adsorbent for optical resolution obtained by graft polymerizing an optically active vinyl monomer of the formula: ##STR1## wherein X is --CONH--, --COO-- or --NHCOO--, R.sup.1 is a hydrogen atom or a methyl group, and each of R.sup.2 to R.sup.4 which are different from one another, is a hydrogen atom, a hydrocarbon group or an alkoxycarbonyl group, or R.sup.2 and R.sup.3 together form a ring, to a crosslinked polymer carrier having groups to which said monomer is graft polymerizable.