Abstract: A medical information system includes a processor on a side of a medical image diagnostic device. The processor acquires supplementary information as structured information associated with image data acquired using the medical image diagnostic device, the supplementary information being new information on a subject to be imaged. The processor notifies at least one management server that manages patient information of the supplementary information via a network in response to the acquisition of the supplementary information, the patient information being information unique to the subject.

Abstract: One disadvantage of adeno-associated virus (AAV) is low gene expression efficiency due to delayed expression of the inserted gene. Provided is a vector plasmid for producing a vector genome to be inserted into an adeno-associated virus (AAV). The vector plasmid is provided with a vector genome cassette as a template of the vector genome, and the vector genome cassette is provided with: (1) an expression cassette including a nucleic acid molecule encoding a target gene and (b) a nucleic acid molecule encoding an expression regulatory region that allows expression of the target gene; and (2) two nucleic acid molecules positioned on both sides of the expression cassette and encoding inverted terminal repeats (ITRs). Also provided is a pharmaceutical composition containing the AVV vector, for treating or preventing an eye disease or disease associated with same.

Abstract: There is provided an objective optical system that is easy to produce, capable of forming optical images that can be observed without difficulties while small in size. The objective optical system includes, in order from the object side, a flat plate OP1, an aperture stop S, and a substantially hemispherical planoconvex lens L1 having an outer diameter substantially equal to the outer diameter of the flat plate. The flat plate and the planoconvex lens L1 are cemented together with the aperture stop between. The objective optical system satisfies the following conditional expressions (1), (2), and (3): 0.3<IH/Dp<0.45 (1) 1.7<1+Dp×?r/(2×IH)<2.1 (2) 0.9<NL/(1+Dp×?r/(2×IH))<1.1 (3).

Abstract: The endoscope illuminating optical system includes a transparent resin member, and a lighting member which outputs illumination light. The transparent resin member has a through hole in which an image sensor is disposed, a non-through hole in which the lighting member is disposed, an internal optical surface which is formed at an interior of the transparent resin member by the non-through hole, and an outer surface from which the illumination light incident on the transparent resin member via the internal optical surface, is emerged toward an object. The outer surface has a curved-surface area through which the illumination light passes, and the curved-surface area has a boundary with the through hole. In the curved-surface area, a displacement of each point of the curved-surface area from the boundary occurs in a direction away from the object.

Abstract: An image pickup optical system includes an image pickup field of view in which part of an endoscope is reflected, an aperture stop and a peripheral light reduction stop. The peripheral light reduction stop is positioned in an optical axis direction satisfying Conditional Expression (1), in the peripheral light reduction stop, when a side on which part of the endoscope exists in the image pickup field of view is a first direction and a side on which no part of the endoscope exists in the image pickup field of view is a second direction, an opening portion of the peripheral light reduction stop satisfies Conditional Expression (2), and a peripheral light reduction quantity in the second direction is smaller than a peripheral light reduction quantity in the first direction by shielding no effective luminous flux in the second direction or reducing shielding quantity of the effective luminous flux, 0.5<|Hch/Haxm|<5??(1), ?1.2<(La?|Hch|)/|Haxm|<0.6??(2).

Abstract: One disadvantage of adeno-associated virus (AAV) is low gene expression efficiency due to delayed expression of the inserted gene. Provided is a vector plasmid for producing a vector genome to be inserted into an adeno-associated virus (AAV). The vector plasmid is provided with a vector genome cassette as a template of the vector genome, and the vector genome cassette is provided with: (1) an expression cassette including a nucleic acid molecule encoding a target gene and (b) a nucleic acid molecule encoding an expression regulatory region that allows expression of the target gene; and (2) two nucleic acid molecules positioned on both sides of the expression cassette and encoding inverted terminal repeats (ITRs). Also provided is a pharmaceutical composition containing the AVV vector, for treating or preventing an eye disease or disease associated with same.

Abstract: A dispensing device includes: a primary tank which accommodates a liquid; primary-side pressure adjusting means for adjusting pressure in an interior of the primary tank; a plurality of branch flow paths connected to the primary tank; and a plurality of secondary tanks which are provided corresponding to the plurality of branch flow paths, respectively, and each of which is connected to a corresponding branch flow path.

Abstract: An image pickup optical system includes an image pickup field of view in which part of an endoscope is reflected, an aperture stop and a peripheral light reduction stop. The peripheral light reduction stop is positioned in an optical axis direction satisfying Conditional Expression (1), in the peripheral light reduction stop, when a side on which part of the endoscope exists in the image pickup field of view is a first direction and a side on which no part of the endoscope exists in the image pickup field of view is a second direction, an opening portion of the peripheral light reduction stop satisfies Conditional Expression (2), and a peripheral light reduction quantity in the second direction is smaller than a peripheral light reduction quantity in the first direction by shielding no effective luminous flux in the second direction or reducing shielding quantity of the effective luminous flux, 0.5<|Hch/Haxm|<5 ??(1), ?1.2<(La?|Hch|)/|Haxm|<0.6 ??(2).

Abstract: Retinal detachment sometimes occurs during the aging process of retinal degeneration 6 model mouse (rd6 model mouse). The present invention provides a method for obtaining a retinal degeneration (rd) model mouse having a low risk of causing retinal detachment, including: acquiring tissue data about a retinal tissue in an rd model mouse by using a retinal examination means; determining whether or not the tissue data meets an evaluation criterion; and selecting the rd model mouse, the tissue data of which meets the evaluation criterion.

Abstract: An objective optical system includes in order from an object side to an image side, a first lens having a negative refractive power, an aperture stop, and a second lens having a positive refractive power. An image-side surface of the first lens is a surface which is concave toward the image side, and an image-side surface of the second lens is a surface which is convex toward the image side, and following conditional expressions (1), (2), (3), (4), (5), (6), and (7) are satisfied: 0.6<LL1is/LsL2i<1.25??(1) ?3<(LL1is/RL1i)×(LsL2i/RL2i)<?1.25??(2) ?2<fL22/(f×fL1)<?1.35??(3) 2<(nd1?1.63)×(?d1?31)??(4) 5<(n2?1.45)×(?d2?31)??(5) 1.63<nd1, and, 31<?d1??(6) 1.45<nd2, and, 31<?d2??(7).

Abstract: The present invention relates to a hydrogen molecule-containing prophylactic or therapeutic agent for oxidative damage for use in intraocular surgery, which is intended to provide a prophylactic or therapeutic agent for oxidative damage, which is administered when phacoemulsification cataract surgery is performed.

Abstract: A dispensing device includes: a primary tank which accommodates a liquid; primary-side pressure adjusting means for adjusting pressure in an interior of the primary tank; a plurality of branch flow paths connected to the primary tank; and a plurality of secondary tanks which are provided corresponding to the plurality of branch flow paths, respectively, and each of which is connected to a corresponding branch flow path.

Abstract: A photographing device attachable to a moving body includes: a first control section configured to predict and obtain a change in physical quantity based on an alteration in a photographing state; and a communication control section configured to transmit information related to the change in the physical quantity. The photographing device improves stability in the moving body and stability of photographing. Information related to influence on the moving body based on a change in an outer shape and a change in a position of the center of gravity of the photographing device mounted on the moving body is shared by the moving body to improve the stability in the moving body and the stability of photographing.

Abstract: An endoscope illuminating optical system to be disposed at a front end of an insertion portion of an endoscope includes a lens formed by a transparent-resin molding having a function of a front-end frame, which is configured to be disposed at a front-end side of the insertion portion, and a light guide which is disposed adjacent to the lens. A surface of the lens facing the light guide is a composite concave surface in which two axisymmetric concave surfaces are overlapped, and has a gourd-shaped effective cross-section. An effective range of a distal end surface of the light guide has a shape of an ellipsoid, or an oval, or a gourd, and has a long axis in a longitudinal direction of the gourd-shaped effective cross-section of the surface of the lens facing the light guide side, and a short axis in a direction perpendicular to the long axis. The cross-section of the composite concave surface includes an end surface of the light guide.

Abstract: The endoscope illuminating optical system includes a transparent resin member, and a lighting member which outputs illumination light. The transparent resin member has a through hole in which an image sensor is disposed, a non-through hole in which the lighting member is disposed, an internal optical surface which is formed at an interior of the transparent resin member by the non-through hole, and an outer surface from which the illumination light incident on the transparent resin member via the internal optical surface, is emerged toward an object. The outer surface has a curved-surface area through which the illumination light passes, and the curved-surface area has a boundary with the through hole. In the curved-surface area, a displacement of each point of the curved-surface area from the boundary occurs in a direction away from the object.

Abstract: A photographing device attachable to a moving body includes: a first control section configured to predict and obtain a change in physical quantity based on an alteration in a photographing state; and a communication control section configured to transmit information related to the change in the physical quantity. The photographing device improves stability in the moving body and stability of photographing. Information related to influence on the moving body based on a change in an outer shape and a change in a position of the center of gravity of the photographing device mounted on the moving body is shared by the moving body to improve the stability in the moving body and the stability of photographing.

Abstract: A medical image processing apparatus includes an image acquisition part and a display processing part. The image acquisition part is configured to acquire plural series, each having frames of medical image data corresponding to at least one of slice positions and time phases. The display processing part is configured to perform display processing to display image data in a region of interest of at least one frame of first medical image data belonging to a first series out of the plural series. The image data in the region of interest are overlapped with a region of at least one frame of second medical image data belonging to another series. The region of the at least one frame of the second medical image data is different from a region corresponding to the region the interest.

Abstract: There is provided an endoscope illuminating optical system in which a favorable light-distribution can be achieved even in a case of a wide in-water angle of view, and which is suitable for mounting in a medical endoscope having a thin diameter.

Abstract: There is provided an endoscope objective optical system having a thin diameter, a wide in-water angle of view, a small variation in the angle of view, and a short overall length of the optical system. The endoscope objective optical system includes in order from an object side, a front group GF having a negative refractive power, an aperture stop, and a rear group GR having a positive refractive power, wherein the front group includes a first negative lens L1 and a second negative lens L2, and the following conditional expressions (1), (2), (3?), and (4) are satisfied: 1<Iw/ft<1.8??(1), 4<Lt/Iw<9.5??(2), 1.49?Lsf/ft?2.30??(3?), and 0.38<?La/Lsf<0.6??(4).

Abstract: There is provided an endoscope objective optical system having a thin diameter, a wide in-water angle of view, a small variation in the angle of view, and a short overall length of the optical system. The endoscope objective optical system includes in order from an object side, a front group GF having a negative refractive power, an aperture stop, and a rear group GR having a positive refractive power, wherein the front group includes a first negative lens L1 and a second negative lens L2, and the following conditional expressions (1), (2), (3?), and (4) are satisfied: 1<Iw/ft<1.8??(1), 4<Lt/Iw<9.5??(2), 1.49?Lsf/ft?2.30??(3?), and 0.38<?La/Lsf<0.6??(4).