Patents by Inventor Tsuyoshi Shiio

Tsuyoshi Shiio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Platinum complexes and uses therewith
    Patent number: 5041579
    Abstract: Platinum complexes of cis-diaminocyclohexanol or cis-diaminocyclohexane, with the exclusion of platinum complexes of 2-deoxystreptamine, having high anti-tumor activity, low toxicity, water-solubility and exhibiting no cross-resistance to cis-platin.
    Type: Grant
    Filed: September 23, 1988
    Date of Patent: August 20, 1991
    Assignee: Ajinomoto Co., Inc.
    Inventors: Seiichi Nishi, Kazuo Ohishi, Kunisuke Izawa, Tsuyoshi Shiio, Tetsuo Suami
  • Anthracycline compounds bound to hydrophilic polypeptides
    Patent number: 4642335
    Abstract: This invention relates to an antitumor composition of anthracycline compounds bonded to hydrophilic polypeptides having a molecular weight between 10,000 and 15,000.
    Type: Grant
    Filed: May 28, 1985
    Date of Patent: February 10, 1987
    Assignee: Ajinomoto Co., Inc.
    Inventors: Shigeyoshi Miyashiro, Takao Kida, Tsuyoshi Shiio, Hiroshiro Shibai
  • Streptothricin-group compounds
    Patent number: 4560748
    Abstract: A streptothricin-group compound having the formula: ##STR1## in which R represents ##STR2## is disclosed along with methods for producing this compound and a microorganism useful in its production.
    Type: Grant
    Filed: June 3, 1983
    Date of Patent: December 24, 1985
    Assignee: Ajinomoto Company Incorporated
    Inventors: Shigezo Udaka, Shigeyoshi Miyashiro, Kazuo Hirayama, Toshihiko Ando, Asao Murai, Tsuyoshi Shiio, Takao Kida, Hiroshiro Shibai
  • High molecular weight antitumor antibiotic AN-7D
    Patent number: 4507282
    Abstract: A high molecular weight peptide antibiotic designated as AN-7D which is effective as an agent.
    Type: Grant
    Filed: June 10, 1983
    Date of Patent: March 26, 1985
    Assignee: Ajinomoto Co., Inc.
    Inventors: Shigezo Udaka, Shigeyoshi Miyashiro, Eikou Shimizu, Tsuyoshi Shiio
  • Stable aqueous solutions of glucans and glucan derivatives capable of inhibiting sarcoma in mice
    Patent number: 4207312
    Abstract: The glucans and glucan derivatives which inhibit the growth of sarcoma 180 in mice are only sparingly soluble in water, and their aqueous solutions are unstable. In the presence of 0.1 to 1.0 g/dl water soluble dextran, hydroxyethyl starch, carboxymethyl cellulose, or polyethylene glycol, they form relatively concentrated and stable solutions, particularly in the presence of hexoses, pentoses or sugar alcohols having 5 or 6 carbon atoms.
    Type: Grant
    Filed: February 2, 1976
    Date of Patent: June 10, 1980
    Assignees: Ajinomoto Co. Ltd., Morishita Pharmaceuticals Co. Ltd.
    Inventors: Mitsuharu Fujii, Tatsuo Kuoka, Tatsuo Setsuta, Yutaka Iwao, Yasumi Yugari, Tsuyoshi Shiio, Takashi Yoshihama, Junji Hamuro