Abstract: The present embodiments provide apparatus and systems suitable for coupling a graft member to tissue. A wire having a proximal end and a distal end are provided, each having a delivery state suitable for delivery and further comprising a deployed state. In the deployed state, the distal end is configured to engage tissue at a first location, and the proximal end is configured to engage the graft member to secure the graft member to the tissue. Optionally, a loop member may be provided for receiving a suture for further securing the graft member to the tissue. The present embodiments may also be used without a graft member to close openings in tissue.

Abstract: Medical systems, devices and methods are disclosed for suturing a perforation in tissue, that may be employed endoscopically and/or laparoscopically, and that offer simple, reliable and controllable placement of suture around a perforation for complete closure thereof. One embodiment of the medical system generally includes an endoscope, an endcap, a needle, a suture, and first and second grip systems configured for relative translation to selectively pass the needle between the first and second grip systems.