Patents by Inventor Uday Rajaram Bapat

Uday Rajaram Bapat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of a benzazepine derivative
    Patent number: 9428461
    Abstract: Provided is an industrially scalable process for the preparation of a benzazepine derivative, namely, 7-chloro-5-hydroxy-1-[2-methyl-4-(2-methyl benzoyl amino) benzoyl]-2,3,4,5-tetrahydro-1H-1-benzazepine (generically referred as Tolvaptan).
    Type: Grant
    Filed: October 20, 2014
    Date of Patent: August 30, 2016
    Assignee: RPG LIFE SCIENCES LIMITED
    Inventors: Uday Rajaram Bapat, Ranjan Prasad Srivastava, Pravin Chaburao Kolhe, Pravin Ganpat Talekar
  • PROCESS FOR THE PREPARATION OF A BENZAZEPINE DERIVATIVE
    Publication number: 20150112059
    Abstract: Provided is an industrially scalable process for the preparation of a benzazepine derivative, namely, 7-chloro-5-hydroxy-1-[2-methyl-4-(2-methyl benzoyl amino) benzoyl]-2,3,4,5-tetrahydro-1H-1-benzazepine (generically referred as Tolvaptan).
    Type: Application
    Filed: October 20, 2014
    Publication date: April 23, 2015
    Inventors: Uday Rajaram BAPAT, Ranjan Prasad Srivastava, Pravin Chaburao Kolhe, Pravin Ganpat Talekar
  • NOVEL COMPOUNDS AS DPP-IV INHIBITORS AND PROCESS FOR PREPARATION THEREOF
    Publication number: 20130137852
    Abstract: The present invention relates to process for preparation of novel compounds which are acting as inhibitors of dipeptidyl peptidase-IV enzyme and is depicted by the structural formula as given below: Formula VI. Which are useful in the treatment or prevention of diseases in which the dipeptidylpeptidase-IV enzyme is involved, such as diabetes and particularly type-2 diabetes.
    Type: Application
    Filed: August 3, 2011
    Publication date: May 30, 2013
    Applicant: Cadila Corporate Campus
    Inventors: Bakulesh Mafatlal Khamar, Nirav Kishorbhai Joshi, Chandan Hardhan Singh, Uday Rajaram Bapat, Bipin Dhanjibhai Gadhiya, Nirav Sureshbhai Sagar, Indravadan Ambalal Modi
  • Process for preparation of 9-hydroxy-3-(2-chloroethyl)-2-methyl-4H-pyrido[1,2-A]pyrimidin-4-one hydrochloride
    Patent number: 8071767
    Abstract: Described herein is an improved, commercially viable and industrially advantageous process for the preparation of paliperidone intermediate 9-hydroxy-3-(2-chloroethyl)-2-methyl-4h-pyrido[1,2-a]pyrimidin-4-one and its hydrochloride salt. The process provides the paliperidone intermediate in higher yield and reduced reaction time compared to the previously disclosed processes, thereby providing for production of paliperidone and its pharmaceutically acceptable acid addition salts in high purity and in high yield.
    Type: Grant
    Filed: January 8, 2008
    Date of Patent: December 6, 2011
    Assignee: Actavis Group PTC EHF
    Inventors: Uday Rajaram Bapat, Munusamy Jayamani, Sivaji Ravisaravanan, Vigneshwara Ravisankar
  • PROCESS FOR THE PREPARATION OF ALFUZOSIN AND SALTS THEREOF
    Publication number: 20100174073
    Abstract: The present invention relates to novel N-[3-[(4-acyl-/aroyl-substituted amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamide derivatives, and a process for the preparation thereof. The novel compounds are useful for preparing alfuzosin or a pharmaceutically acceptable salt thereof in high yield and purity.
    Type: Application
    Filed: May 2, 2008
    Publication date: July 8, 2010
    Applicant: ACTAVIS GROUP PTC EHF
    Inventors: Uday Rajaram Bapat, Jose Paul Potams, Narasimhan Subramanian, Jon Valgeirsson
  • PROCESS FOR PREPARATION OF 9-HYDROXY-3-(2-CHLOROETHYL)-2-METHYL-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE HYDROCHLORIDE
    Publication number: 20100004447
    Abstract: Described herein is an improved, commercially viable and industrially advantageous process for the preparation of paliperidone intermediate 9-hydroxy-3-(2-chloroethyl)-2-methyl-4h-pyrido[1,2-a]pyrimidin-4-one and its hydrochloride salt. The process provides the paliperidone intermediate in higher yield and reduced reaction time compared to the previously disclosed processes, thereby providing for production of paliperidone and its pharmaceutically acceptable acid addition salts in high purity and in high yield.
    Type: Application
    Filed: January 8, 2008
    Publication date: January 7, 2010
    Applicant: ACTAVIS GROUP PTC EHF
    Inventors: Uday Rajaram Bapat, Munusamy Jayamani, Sivaji Ravisaravanan, Vigneshwara Ravisankar
  • Highly Pure Paliperidone or a Pharmaceutically Acceptable Salt Thereof Substantially Free of Keto Impurity
    Publication number: 20090247553
    Abstract: Provided herein is a highly pure paliperidone or a pharmaceutically acceptable salt thereof substantially free of keto impurity, 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-2-methyl-7,8-dihydro-6H-pyrido[1,2-a]pyrimidin-4,9-dione, a process for the preparation thereof, and pharmaceutical compositions comprising highly pure paliperidone or a pharmaceutically acceptable salt thereof substantially free of keto impurity.
    Type: Application
    Filed: March 26, 2009
    Publication date: October 1, 2009
    Applicant: ACTAVIS GROUP PTC EHF
    Inventors: Uday Rajaram Bapat, Munusamy Jayamani, Sivaji Ravisaravanan, Vishal Amrutlal Sodha, Jon Valgeirsson
  • Paliperidone Polymorphs
    Publication number: 20090061005
    Abstract: Described herein are novel polymorphic forms of paliperidone, processes for preparing the novel forms and use thereof. Also provided are processes for the preparation of novel polymorphic forms of paliperidone and the use thereof in the preparation of pharmaceutical compositions.
    Type: Application
    Filed: August 20, 2008
    Publication date: March 5, 2009
    Applicant: ACTAVIS GROUP PTC EHF
    Inventors: Uday Rajaram Bapat, Jayamani Munusamy, Sivaji Ravisaravanan, Vigneshwara Ravisankar, Jon Valgeirsson