Abstract: The present invention relates to a composite comprising an elastic polyurethane molding with compact surface and with cellular core and rubber, capable of production via introduction of a reaction mixture, obtainable via mixing of (a) organic polyisocyanates with (b) at least one compound having at least two reactive hydrogen atoms, (c) chain extenders and/or crosslinking agents, (d) blowing agents, (e) catalysts, (f) hyperbranched polymers, and (g) if appropriate, other auxiliaries and/or additives, into a mold, comprising rubber, and also to a process for production of these composite materials, and to the use of these composite materials as shoe soles.

Abstract: The selective determination of .alpha.-ketoisocaproate in samples of body fluids, especially in serum, is achieved, without previous separation, directly in the fluid and in the presence of NADH, by means of a KIC-specific D-.alpha.-hydroxy-isocaproic dehydrogenase that originates specifically from strains of Lactobacillus casei producing this enzyme, in particular strains of Lactobacillus casei subspecies pseudoplantarum or casei. The KIC determination is used, in particular, for diagnosing maple syrup urine disease. Expedient for this purpose are analytical kits which have a divisible stock of D-.alpha.-hydroxyisocaproic dehydrogenase from Lactobacillus casei, in particular from the Lactobacillus casei (DSM 20008).