Abstract: The present invention relates to Map4K1 inhibitors of formula (I) (I), wherein A, E, G, Q, R1, R2 and R4 have the same meaning as defined in the description, to pharmaceutical compositions and combinations comprising the compounds according to the invention, and to the prophylactic and therapeutic use of the inventive compounds, respectively to the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for neoplastic disorders, respectively cancer or conditions with dysregulated immune responses or other disorders associated with aberrant MAP4K1 signaling, as a sole agent or in combination with other active ingredients.

Abstract: A device for separating liquid from a volume flow of a gas-liquid mixture may include a separating element and a deflection arrangement for deflecting the volume flow in a direction of the separating element to precipitate liquid on the separating element and thereby separate the liquid. The deflection arrangement may comprise a flow channel that extends axially away from a volume flow inlet and comprises an aperture area that extends axially on the flow channel. The aperture area may be at least partly covered by a covering means that is movable relative to the aperture area. The covering means may be movable to different extents at two axially-spaced locations to influence a magnitude of a part volume flow of the deflected volume flow flowing out of the flow channel through the aperture area at one axial location differently than at another axial location.

Abstract: A valve drive may include a sliding cam element that is held on a carrier shaft so as to be axially displaceable along an axis of rotation of the carrier shaft. The sliding cam element may include at least one cam profile group with cam profile sections of mutually different form. The valve drive may further include a pick-off element by way of which a control movement can be picked off from the cam profile sections and transmitted to a valve. The sliding cam element may also include a second cam profile group that is similar or identical to the first cam profile group and, which for the joint control of one valve, may interact with the pick-off element.

Abstract: A device for separating liquid from a volume flow of a gas-liquid mixture may include a separating element and a deflection arrangement for deflecting the volume flow in a direction of the separating element to precipitate liquid on the separating element and thereby separate the liquid. The deflection arrangement may comprise a flow channel that extends axially away from a volume flow inlet and comprises an aperture area that extends axially on the flow channel. The aperture area may be at least partly covered by a covering means that is movable relative to the aperture area. The covering means may be movable to different extents at two axially-spaced locations to influence a magnitude of a part volume flow of the deflected volume flow flowing out of the flow channel through the aperture area at one axial location differently than at another axial location.

Abstract: An oil separation device for separating oil from a gas stream for ventilating a crankcase of a combustion engine may include an inflow side and an outflow side. The inflow side can be fluidically connected to the crankcase of the combustion engine and may receive the gas stream laden with oil. The outflow side can be fluidically connected to an intake tract of the combustion engine and may receive the gas stream substantially purged of oil. The device may include a first control member for varying a first flow cross section of the gas stream and controlled by a gas pressure in the crankcase. The device may have a second control member for varying a second flow cross section of the gas stream positioned downstream of the first flow cross section, wherein the second control member is controlled by a vacuum in the intake tract of the combustion engine.

Abstract: An oil-separating device for crankcase ventilation of an internal combustion engine may include a hollow member that extends axially in a longitudinal axis and through which a gas flow charged with oil can flow. The gas flow may flow against an oil separation ring disposed within or formed in the hollow member. The hollow member may contain a substantially rotationally symmetrical flow guiding member that has a flow projection located in the longitudinal axis and that has a flow contour that radially increases in a downstream direction so that gas can flow around the flow guiding member and so that the gas flow between the flow contour and the inner side of the hollow member can strike the oil separation ring in an accelerated manner.

Abstract: An oil separator may be used in a variety of contexts, one of which is for crankcase ventilation of an internal combustion engine. The oil separator may include a hollow member that extends along a longitudinal axis and is configured to receive a gas flow that is charged with oil. The oil separator may also include an oil separation member disposed within the hollow member and against which the gas flow flows. A redirection member may be disposed proximate the oil separation member in the hollow member, wherein the redirection member redirects at least a portion of the gas flow traveling substantially along the longitudinal axis radially outwards so as to impact an inner side of the oil separation member. As a result of an impactor effect from the gas flow striking the oil separation member as well as the inertia of the oil, the oil may remain in and/or pass through the oil separation member.

Abstract: A valve drive may include a sliding cam element that is held on a carrier shaft so as to be axially displaceable along an axis of rotation of the carrier shaft. The sliding cam element may include at least one cam profile group with cam profile sections of mutually different form. The valve drive may further include a pick-off element by way of which a control movement can be picked off from the cam profile sections and transmitted to a valve. The sliding cam element may also include a second cam profile group that is similar or identical to the first cam profile group and, which for the joint control of one valve, may interact with the pick-off element.

Abstract: An oil separation device for separating oil from a gas stream for ventilating a crankcase of a combustion engine may include an inflow side and an outflow side. The inflow side can be fluidically connected to the crankcase of the combustion engine and may receive the gas stream laden with oil. The outflow side can be fluidically connected to an intake tract of the combustion engine and may receive the gas stream substantially purged of oil. The device may include a first control member for varying a first flow cross section of the gas stream and controlled by a gas pressure in the crankcase. The device may have a second control member for varying a second flow cross section of the gas stream positioned downstream of the first flow cross section, wherein the second control member is controlled by a vacuum in the intake tract of the combustion engine.

Abstract: An oil-separating device for crankcase ventilation of an internal combustion engine may include a hollow member that extends axially in a longitudinal axis and through which a gas flow charged with oil can flow. The gas flow may flow against an oil separation ring disposed within or formed in the hollow member. The hollow member may contain a substantially rotationally symmetrical flow guiding member that has a flow projection located in the longitudinal axis and that has a flow contour that radially increases in a downstream direction so that gas can flow around the flow guiding member and so that the gas flow between the flow contour and the inner side of the hollow member can strike the oil separation ring in an accelerated manner.

Abstract: An oil separator may be used in a variety of contexts, one of which is for crankcase ventilation of an internal combustion engine. The oil separator may include a hollow member that extends along a longitudinal axis and is configured to receive a gas flow that is charged with oil. The oil separator may also include an oil separation member disposed within the hollow member and against which the gas flow flows. A redirection member may be disposed proximate the oil separation member in the hollow member, wherein the redirection member redirects at least a portion of the gas flow traveling substantially along the longitudinal axis radially outwards so as to impact an inner side of the oil separation member. As a result of an impactor effect from the gas flow striking the oil separation member as well as the inertia of the oil, the oil may remain in and/or pass through the oil separation member.

Abstract: An oil-laden gas stream flows axially through a tube shaft formed with at least one radially throughgoing inner oil-discharge port and, axially downstream therefrom, with at lest one radially throughgoing inner gas-discharge port. A bearing supports the tube shaft for rotation about the axis and is formed axially level with the ports with respective radially throughgoing outer oil-discharge and gas-discharge ports. An oil separator inside the tube shaft axially between the oil-discharge ports and the gas-discharge ports is oriented to deflect oil particles from the stream radially outward such that the oil flows out through the inner and outer oil-discharge ports and the gas stream can flow downstream out through the gas-discharge ports.

Abstract: In a method for operating an adsorption dryer, a process air flow, generated by at least one blower, is routed at least at times through an adsorption apparatus and over a textile goods in care during a textile care process in a “dry” operating mode to thereby charge a reversibly dehydratable adsorbent of the adsorption apparatus with moisture. A charge state of the adsorbent with water is detected and is displayed at least after the end of the “drying” textile care process. The absorbent is desorbed at least in part during a subsequent, selected and started textile care process in a “refresh” operating mode, and the desorbed moisture is routed as a moist process air flow into a receptacle for refreshing textile goods which are stored or hung in a stationary manner.

Abstract: In a method for operating an adsorption dryer, a process air flow, generated by at least one blower, is routed at least at times through an adsorption apparatus and over a textile goods in care during a textile care process in a “dry” operating mode to thereby charge a reversibly dehydratable adsorbent of the adsorption apparatus with moisture. A charge state of the adsorbent with water is detected and is displayed at least after the end of the “drying” textile care process. The absorbent is desorbed at least in part during a subsequent, selected and started textile care process in a “refresh” operating mode, and the desorbed moisture is routed as a moist process air flow into a receptacle for refreshing textile goods which are stored or hung in a stationary manner.

Abstract: The invention relates to a shaft body (2) that is rotatably mounted in a bearing unit (4), comprising an oil separator unit that is integrated into a cavity (3) of the shaft body (2). According to the invention, at least one discharge opening (3a; 3b) is provided in the case of the shaft body (2), said opening communicating with a drain channel (4a; 4b) of the bearing unit (4).

Abstract: An automated circuit board assembly system includes at least one movable circuit board receiver that is equipped with an empty circuit board or a hybrid circuit which is transported towards an uptake location at which components are assembled to the board, and an uptake mechanism positioned at the uptake location which detects the circuit board position in preparation for the assembly process. An alignment device positions the circuit board receiver in a predetermined directional position at the uptake location.

Abstract: For gluing a circuit component (17) to a circuit board (1), at first at least one fore-running adhesive dot (14) is placed within a contact area (2) between the circuit component (17) and the circuit board (1), then adhesive dots (4) are placed in a regular pattern, and finally the adhesive dots (4) are brought to merge by pressing the circuit component (17) and the circuit board (1) against each other.

Abstract: A circuit component (1) is glued to the circuit substrate (2) by the following steps: a) seizing a circuit component (1) using a grip-per (4); b) moving the gripper (4) towards the surface of the circuit substrate (2) up to a target distance from the surface at which adhesive (3) applied between the circuit component (1) and the circuit substrate (2) is pressed; C) releasing the circuit component (1) and removing the gripper (4) from the circuit component (1); d) turning the gripper (4) around an axis (A) perpendicular to the surface of the circuit substrate (2); e) moving the gripper (4) into the target distance again; and f) removing the gripper (4) again.

Abstract: A method of gluing a circuit component onto a circuit board. The circuit component has a bottom area with at least one edge for bringing into contact with the circuit board. The distance between the edge and a first line parallel to the edge and an amount of adhesive to be applied per length unit along the line are determined such that, when placing the circuit component on the circuit board,the adhesive advances to the edge but not to a second circuit component adjacent to the edge. The adhesive is applied in the selected quantity along the first line and along further lines which are parallel to the first line and further away from the edge. Then, the circuit component is placed on the circuit board.

Abstract: In a procedure for automatically placing components of a circuit on a base plate based on predefined position data, the position of at least one first reference mark formed at the base plate is detected. A target position for placing a substrate on the base plate is calculated based on the detected position of the first reference mark and the position data, and the substrate is placed at the calculated position. The position of at least one second reference mark formed at the substrate is detected and a target position for placing a further component on the substrate is calculated based on the detected position of the second reference mark and the position data predefined for said component, and the component is placed at the calculated target position.