Patents by Inventor Ulrich Schäfer
Ulrich Schäfer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11999801Abstract: The present invention relates to multispecific antibodies comprising at least three antigen binding sites wherein the third binding site is disulfide stabilized by introduction of cysteine, method for their production, pharmaceutical compositions containing said antibodies and uses thereof.Type: GrantFiled: March 17, 2020Date of Patent: June 4, 2024Assignee: Hoffman-La Roche Inc.Inventors: Ulrich Brinkmann, Wolfgang Schaefer, Klaus Mayer
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Publication number: 20240174683Abstract: The present invention relates to Map4K1 inhibitors of formula (I) (I), wherein A, E, G, Q, R1, R2 and R4 have the same meaning as defined in the description, to pharmaceutical compositions and combinations comprising the compounds according to the invention, and to the prophylactic and therapeutic use of the inventive compounds, respectively to the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for neoplastic disorders, respectively cancer or conditions with dysregulated immune responses or other disorders associated with aberrant MAP4K1 signaling, as a sole agent or in combination with other active ingredients.Type: ApplicationFiled: February 4, 2022Publication date: May 30, 2024Applicants: Bayer Aktiengesellschaft, Deutsches KrebsforschungszentrumInventors: Ulrich LÜCKING, Jeffrey Stuart MOWAT, Ludwig ZORN, Lars WORTMANN, Steffen MÜLLER, Gabriele LEDER, Sandra BERNDT, Judith GÜNTHER, Lara KUHNKE, Antje Margret WENGNER, Rafael CARRETERO, Gerd WOHLFAHRT, Anders FRIBERG, Ulf BÖMER, Roland NEUHAUS, Maren OSMERS, Hideki Miyatake ONDOZABAL, Martina SCHÄFER, Louise EAGLING, Julien LEFRANC, Katrin NOWAK-REPPEL, Rienk OFFRINGA, Peng CHEN, Xuewei WANG, Yuanyuan YAN, Kai THEDE, Nikolay SITNIKOV, Berndt BUCHMANN, Dirk KOSEMUND, Detlef STOECKIGT
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Patent number: 9393218Abstract: The subject of this application is the use of film-forming polyurethanes that are used in hair care agents or mixtures of these polyurethanes with other polymers in pharmaceutical preparations for dermal or transdermal administration of active ingredients, as well as patches and pharmaceutical preparations that contain these hair care polyurethanes.Type: GrantFiled: December 22, 2006Date of Patent: July 19, 2016Assignee: EPINAMICS GMBHInventors: Ines Zurdo Schroeder, Patrick Franke, Stefan Bracht, Claus-Michael Lehr, Ulrich Schäfer
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Publication number: 20120214485Abstract: Methods and systems for emergency registration of a vehicle network access device are disclosed, including monitoring one or more vehicle risk indicators; analyzing the one or more vehicle risk indicators for the likelihood of an emergency; and initiating registration of the vehicle network access device in response to analyzing the one or more vehicle risk indicators.Type: ApplicationFiled: August 26, 2009Publication date: August 23, 2012Applicant: CONTINENTAL AUTOMOTIVE GMBHInventors: Gerhard Wessels, Ulrich Schaefer, Christoph Schmickler
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Publication number: 20100318172Abstract: The present disclosure pertains to a guide wire (1) for guiding intervention devices, the guide wire having a guide wire body (3) and a distal tip portion (10), wherein an expansion element (2) is present having, in an insertion configuration, a first diameter (D1) which is substantially identical to the diameter (d) of the guide wire body(3) and, in an intervention configuration, a second diameter (D2) which is substantially larger than the first diameter.Type: ApplicationFiled: June 10, 2010Publication date: December 16, 2010Inventor: Ulrich Schaefer
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Patent number: 7530188Abstract: The invention is directed to an adapter (29) for attaching an electronic shelf label (26) to a cantilever (22) of a blister hook (20). The adapter (29) has a housing (30) into which the shelf label (26) is inserted, and a suspension device for pivotal mounting of the housing (30) on a cross-strut (24) provided on the free end of the cantilever (22). The suspension device is a yoke (32) that is connected to the housing (30) and has two pliable sleeves (44, 54), each with a free end that is placed around the cross-strut (24) and is snap-locked onto the yoke (32). The adapter (29) is suitable for nearly universal use on various blister hooks of different size and shape. The housing (30) is angularly adjustable relative to the yoke (32) in order to align the product and price display of the shelf label (26) in the observer's viewing direction.Type: GrantFiled: April 1, 2005Date of Patent: May 12, 2009Assignee: Checkpoint Systems, Inc.Inventors: Kai Beilenhoff, Ulrich Schaefer
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Publication number: 20070224879Abstract: The invention is directed to an adapter (29) for attaching an electronic shelf label (26) to a cantilever (22) of a blister hook (20). The adapter (29) has a housing (30) into which the shelf label (26) is inserted, and a suspension device for pivotal mounting of the housing (30) on a cross-strut (24) provided on the free end of the cantilever (22). The suspension device is a yoke (32) that is connected to the housing (30) and has two pliable sleeves (44, 54), each with a free end that is placed around the cross-strut (24) and is snap-locked onto the yoke (32). The adapter (29) is suitable for nearly universal use on various blister hooks of different size and shape. The housing (30) is angularly adjustable relative to the yoke (32) in order to align the product and price display of the shelf label (26) in the observer's viewing direction.Type: ApplicationFiled: April 1, 2005Publication date: September 27, 2007Applicant: CHECKPOINT SYSTEMS, INC.Inventors: Kai Beilenhoff, Ulrich Schaefer
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Patent number: 6495729Abstract: The compounds are (+)- and (−)-2-cyclododecylpropanol and (+)- and (−)-2-cyclododecylpropionic acid, and salts thereof. (−)-2-cyclododecylpropanol is suitable as a fragrance while the virtually odorless (+) enantiomer is suitable as a fixative for other fragrances. The two enantiomers of 2-cyclododecylpropanol are prepared by reduction of the acid function of the enantiomers of 2-cyclododecylpropionic acid.Type: GrantFiled: May 3, 2001Date of Patent: December 17, 2002Assignee: BASF AktiengesellschaftInventors: Klaus Ebel, Wolfgang Krause, Ulrich Schäfer-Lüderssen
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Patent number: 6316676Abstract: The process for the preparation of carbonyl compounds of the formula I where R1 and R2 are a hydrocarbon radical, or R1 and R2 together are an unsubstituted or substituted alkylene group, and X is ═O or two alkoxy groups, comprises oxidizing alcohols of the formula II where R1 to R2 and X are as defined above, with oxygen in the gaseous phase a) at temperatures of from 270 to 600° C. on silver coated catalysts which comprise an abrasion-resistant coating of metallic silver on a core of inert support material, or b) at temperatures of from 450 to 750° C. on silver crystals and/or copper crystals having a particle size of from 0.1 to 2.5 mm for a residence time of at most 0.1 second. Also claimed is an advantageous overall process for the preparation of &agr;-diketones, preferably diacetal, from the corresponding ketone, in particular methyl ethyl ketone, via the carbonyl compounds of the formula I where X is two alkoxy groups.Type: GrantFiled: February 28, 2001Date of Patent: November 13, 2001Assignee: BASF AktiengesellschaftInventors: Werner Aquila, Jörg Botzem, Melanie Brunner, Hartwig Fuchs, Wolfgang Krause, Klaus Pandl, Ulrich Schäfer-Lüderssen
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Patent number: 6242653Abstract: The process for the preparation of carbonyl compounds of the formula I where R1 and R2 are a hydrocarbon radical, or R1 and R2 together are an unsubstituted or substituted alkylene group, and X is=O or two alkoxy groups, comprises oxidizing alcohols of the formula II where R1 to R2 and X are as defined above, with oxygen in the gaseous phase a) at temperatures of from 270 to 600° C. on silver coated catalysts which comprise an abrasion-resistant coating of metallic silver on a core of inert support material, or b) at temperatures of from 450 to 750° C. on silver crystals and/or copper crystals having a particle size of from 0.1 to 2.5 mm for a residence time of at most 0.1 second. Also claimed is an advantageous overall process for the preparation of &agr;-diketones, preferably diacetal, from the corresponding ketone, in particular methyl ethyl ketone, via the carbonyl compounds of the formula I where X is two alkoxy groups.Type: GrantFiled: August 19, 1999Date of Patent: June 5, 2001Assignee: BASF AktiengesellschaftInventors: Werner Aquila, Jörg Botzem, Melanie Brunner, Hartwig Fuchs, Wolfgang Krause, Klaus Pandl, Ulrich Schäfer-Lüderssen
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Patent number: 6234464Abstract: A microencapsulated unsaturated fatty acid or fatty acid compound or mixture of fatty acids and/or fatty acid compounds, and particularly an omega-3-fatty acid or omega-6-fatty acid or an ethyl ester or a glyceride thereof or a mixture of such fatty acids and/or fatty acid compounds. Fatty acid compounds are understood to include derivatives. Particles of the compounds are provided with capsule walls composed of two layers. The inner layer is composed of gelatin A, gelatine B. casein or an alginate, or of a derivative or salt of one of these polymers. The outer layer is composed of gelatin B, gum arabic, pectin or chitosan or a derivative or salt of one of these polymers.Type: GrantFiled: July 7, 1999Date of Patent: May 22, 2001Assignee: K.D. Pharma Bexbech GmbHInventors: Rudolf Krumbholz, Alf Lamprecht, Claus-Michael Lehr, Ulrich Schäfer, Norbert Schirra, Manfred Treitz
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Patent number: 5691892Abstract: A rectifier arrangement for a three-phase generator having at least one power diode allocated to each half-wave of each phase and a cooling arrangement for the power diodes. The power diodes may be designed as diode chips and be arranged between two diametrically opposed heat sinks, while being oriented with respect to polarity and electrically and/or thermally conductive.Type: GrantFiled: February 9, 1995Date of Patent: November 25, 1997Assignee: Robert Bosch GmbHInventors: Friedhelm Meyer, Richard Spitz, Herbert Goebel, Ulrich Schaefer, Vesna Biallas, Anton Mindl, Martin Frey, Henning Stilke, Holger Haussmann, Siegfried Schuler
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Patent number: 4594456Abstract: 3-Hydroxy-.alpha.-cyclocitral derivatives of the general formula I ##STR1## where R.sup.1 is ##STR2## wherein R.sup.2 and R.sup.3 can be identical or different and are each straight-chain or branched alkyl of 1 to 6 carbon atoms, or R.sup.2 and R.sup.3 together form an ethylene or propylene group which can be substituted by methyl or ethyl, processes for their preparation and their use for the preparation of safranal and 3-hydroxy-.beta.-cyclocitral, as well as optically active - cyclocitral derivatives of the general formulae A and B ##STR3## where R.sup.1 is ##STR4## if X is hydrogen and Y is OH, but is otherwise ##STR5## where R.sup.2 and R.sup.3 have the above meanings, and X and Y together are oxygen, or X is hydrogen if Y is OH, and a process for the preparation of optically active 3-oxo-.alpha.-cyclocitral acetals, wherein a mixture of the corresponding racemic 3-oxo-.alpha.-cyclocitral acetals is separated into the optically active compounds by chromatography over a suitable chiral adsorbent.Type: GrantFiled: January 20, 1984Date of Patent: June 10, 1986Assignee: BASF AktiengesellschaftInventors: Ulrich Schaefer-Luederssen, Hagen Jaedicke, Joachim Paust, Manfred Eggersdorfer