Abstract: The invention consists of a device and a method for sectioning of organs and irregular tissue blocks into tissue sections of a predefined thickness and orientation, in one uniform working process. The tissue is embedded into an alginate polymer, which is poured into an embedding container with two opposite arrays of parallel grooves. After hardening, the polymer can be sectioned in slices of a predetermined thickness. This is achieved by razor blade cuts through an array of parallel grooves in the embedding container. Finally, the tissue and alginate polymer can be removed by removing the side of the embedding container resulting in a series of parallel sections of predefined and often equal thickness.