Patents by Inventor Umamaheswararao Jonnalagadda

Umamaheswararao Jonnalagadda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIMERIC ANTIGEN RECEPTORS (CARs) HAVING MUTATIONS IN THE FC SPACER REGION AND METHODS FOR THEIR USE
    Publication number: 20160333108
    Abstract: Adoptive immunotherapy using T cells genetically redirected via expression of chimeric antigen receptors (CARs) is a promising approach for cancer treatment. However, this immunotherapy is dependent in part on the optimal molecular design of the CAR, which involves an extracellular ligand-binding domain connected to an intracellular signaling domain by spacer and/or transmembrane sequences.
    Type: Application
    Filed: March 14, 2014
    Publication date: November 17, 2016
    Inventors: Stephen J. Forman, Christine E. Brown, Umamaheswararao Jonnalagadda, Armen Mardiros